Molecular parasitologist leading a lab at the Whitehead Institute for Biomedical Research & MIT. All opinions my own. š¬š³ļøāššØš“
Cambridge, MA
Joined September 2016
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Weāre looking for someone to lead the implementation and advancement of genome technologies at Whitehead. Spread the word! An opportunity to work with an incredible community of scientists!
Whitehead Institute, a leading biomedical research institute in Cambridge, Massachusetts, is hiring a Genome Technology Core (GTC) Director: wibr.wd1.myworkdayjobs.com/eā¦
Sebastian Lourido retweeted
Whitehead Institute, a leading biomedical research institute in Cambridge, Massachusetts, is hiring a Genome Technology Core (GTC) Director: wibr.wd1.myworkdayjobs.com/eā¦
Sebastian Lourido retweeted
Our parasite genome databases are really gone! The lack of communication and scientific vision ā¦@NIHā© is hard to follow. Colossal mistake! ā¦@parasitesruleā© ā¦@BSPparasitologyā© ā¦@theNASciencesā© ā¦@ScienceMagazineā© ā¦@Natureā© ā¦@NIAIDNewsā©
Sebastian Lourido retweeted
OUT NOW š CRISPR-based functional profiling of the Toxoplasma gondii genome during acute murine infectionš @ChrisJGiuliano @LouridoLab @WhiteheadInst
nature.com/articles/s41564-0ā¦
Sebastian Lourido retweeted
Researchers in @LouridoLab performed the first genome-wide screen of Toxoplasma gondii in live hosts, revealing genes that are important for infection but previously undetected in cell culture experiments: wi.mit.edu/news/genome-wide-ā¦
Very excited to see this out in press. An effort led by @saimamaysidik and Dylan Valleau to understand the function of the CLAMP complex in apicomplexan parasites!
A conserved complex of microneme proteins mediates rhoptry discharge in #Toxoplasma:
@LouridoLab @WhiteheadInst @MITBiology show that three #apicomplexan-specific #microneme proteins form a complex essential for #rhoptry discharge and invasion
embopress.org/doi/full/10.15ā¦
Thank you to our collaborators in the @VernCarruthers and Niles lab for your help in this study.
Read more about the work in this great news article by @gretafriar for @WhiteheadInst wi.mit.edu/news/clamp-compleā¦
Sebastian Lourido retweeted
Very excited to share our latest study using cryo-ET to investigate actin filaments in #Apicomplexan parasites. This allowed us to learn where do these filaments originate at the cell tip and how they could be managed down the cell body to power motility!
nature.com/articles/s41467-0ā¦
Like many joys in science, promotions develop slowly making it hard to know when to mark the occasion. Happy to share my promotion to Associate Professor with Tenure @MITBiology. Immense gratitude to all the lab members, colleagues, and mentors who have made this possible!
I had an incredible time talking about parasites and our labās work with @jvn for their @CuriouswithJVN podcast! podcasts.apple.com/us/podcasā¦
Science friends, has anyone encountered instability or toxicity from NanoLuc-containing plasmids in E. coli?. The troublesome plasmids are not supposed to express NanoLuc in bacteria, but even if they did, there are no intrinsically toxic sequences associated with its ORF.
Sebastian Lourido retweeted
Here is a link to anonymous links which, PIs sign the one(s) as appropriate sites.google.com/view/veupatā¦
.@veupathdb is an essential resource for our field. Please join me in expressing your support for their funding renewal! upenn.co1.qualtrics.com/jfe/ā¦
So excited to see this out in press! Congratulation to you and your lab @ClareHardingLab!
My first senior author paper, and @AghabiDana first first author paper is now out at @NatureComms! She has all of the details (including what changed since the preprint), but thank you to everyone who helped with this paper, its been great!
Sebastian Lourido retweeted
Toxoplasma gondii causes lifelong, occasionally severe infections in humans.
In this news story @LiveScience , I discuss a newly discovered Achillesā heel in the parasite that may bring scientists closer to developing a cure.
livescience.com/health/virusā¦
Thank you @KLNahas for the wonderful write-up of our work! livescience.com/health/virusā¦
Sebastian Lourido retweeted
How it started for @RockefellerUniv grad student Sally Kornbluth and how itās going @MIT
