Proud! A very large sample of rats, modeling the diversity of the human population, to study individual differences in vulnerability or resilience to develop cocaine addiction-like behaviors. Tissues collected and available for follow-up (cocainebiobank.org), GWAS ongoing...
Does Drug Intake Despite Adverse Consequences Really Measure Compulsivity?
There’s a big debate in addiction research: is drug use despite adverse consequences (like punishment) a standalone measure of compulsive behavior, or just part of a larger addiction profile? This new study from the lab suggests it’s the latter — tightly connected to other addiction behaviors.
doi.org/10.7554/eLife.90422 @eLife @UCSDHealth @PsychiatryUcsd @UCSDPharmacy
Lieselot Carrette retweeted
Hey twitter do your thing!
I took a candid pic of a man proposing to his girlfriend on a remote rocky cove by playa sucia near Cabo Rojo in Puerto Rico today 12/10 I took their number to send them my pics but for some reason it doesn’t work. Retweet and help me find them!
Lieselot Carrette retweeted
New paper on @PsychopharmEBPS with @SedighimSharona, @brainaddiction, @LotCarrett in collaboration with @yavinshaham and @MarcoVenniro showing that highly addicted rats under the influence of cocaine increase their drug choices over palatable food link.springer.com/article/10… – at San Diego, CA
Lieselot Carrette retweeted
#eNeuro: To address the common hurdle of obtaining longitudinal samples in addiction research, @PsychiatryUcsd researchers have created two free, unique biobanks containing >20,000 samples collected before, during, and after chronic drug use in rats.
eneuro.org/lookup/DOI/10.152…
Lieselot Carrette retweeted
A precious gift to the community - merci!
The cocaine and oxycodone biobanks offer genetically and behaviorally characterized, longitudinally, and cross-sectionally diverse samples to researchers free of charge.
eneuro.org/content/early/202…
Lieselot Carrette retweeted
Excited to start the 2020 with a new paper in @PNASNews showing that small molecules that target the N/OFQ system might be useful for the treatment of opioid use disorder. Great job @kallupi_marsida @LotCarrett @JenniKononoff @AbePalmer @brainaddiction pnas.org/content/early/2020/… – at North Bethesda, MD
Lieselot Carrette retweeted
Did you know clinical trials for Anavex 2-73, Ketamine and Epidiolex are recruiting children and adults with Rett syndrome at sites across the country? A clinical trial for Trofinetide is slated to begin enrolling later this year. Learn more at: rettsyndrome.org/for-familie…
A thank you goes out to my Rett mice 🐁 especially the females #femalemousemodel #rettsyndrome #curerett pnas.org/content/early/2018/…
Excited to present on potential RNA therapeutics for X linked disease on poster 89 #RNATx2018
Lieselot Carrette retweeted
Kingston talk:
Polycomb compacts
Target genes into domains
Distinct from the TADs
#KSepigen
Lieselot Carrette retweeted
Approved #genetherapy may create "genetically engineered Europeans not eating genetically engineered food" touché, @geochurch #gchurchchat