Patients to benefit from faster access to medicines as UK moves away from animal testing in science gov.uk/government/news/patie…
A study of the hearts of Greenland sharks has found that the long-lived deep-sea predator has massive accumulations of ageing markers, such as severe scarring, but this doesn't appear to affect their health or longevity
newscientist.com/article/251…
Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians
pmc.ncbi.nlm.nih.gov/article…
Superagers Have at Least Two Key Genetic Advantages, Study Reveals : ScienceAlert sciencealert.com/superagers-…
Melatonin attenuates atherosclerotic plaque vulnerability through SIRT6-dependent regulation of vascular smooth muscle cells senescence - ScienceDirect sciencedirect.com/science/ar…
Science-Backed Longevity Supplements: The Best Anti-Aging Vitamins for Powerful Healthy Aging Support medicaldaily.com/science-bac…
Western Hunter-Gatherer genetic ancestry contributes to human longevity in the Italian population
In particular, we showed a greater contribution from Western Hunter-Gatherer-related ancestry to Italian centenarians.
link.springer.com/article/10…
Targeting mitochondrial autophagy for anti-aging
nature.com/articles/s41420-0…
Bacteria against Cancer - Josh Mitteldorf scienceblog.com/joshmitteldo…
World's Healthiest Man Bryan Johnson Achieves 12-Year Biological Age Reversal in Just 500 Days Using HRV Optimization - Health Science Institute us.scienceinhealth.com/2025/…
Food additive emulsifiers and cancer risk: Results from the French prospective NutriNet-Santé cohort - PMC pmc.ncbi.nlm.nih.gov/article…
Longevity retweeted
My magic mushroom longevity experiment found a metabolic reset button in the brain. We expected brain changes, but not a potential metabolic breakthrough.
The discovery: my blood glucose control dramatically improved.
+ before: top 2% of population
+ after: top 0.2% of population
+ better than 99.75% of 18-25 yr olds
+ mean glucose dropped 8%
+ time above 125 mg/dL: zero min
+ variability dropped 11%
This single session reduced my estimated HbA1c by 6.8% from 4.7% to 4.4%.
Why does this matter? We treat diabetes and metabolic dysfunction with chronic daily medication (Metformin, Insulin, GLP-1s). This data suggests that a neuroplastic event might have downstream effects on the liver and pancreas that mimic or exceed these drugs.
For context, taking Metformin daily takes 6 months to drop it 10-15%.
This is a first in-human observation, with comparable pre-clinical evidence existing only in rodents.



