Clinical Nephrologist @ University Hospital of Cologne & avid birder. Tweets are my own.
Köln
Joined April 2009
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Proud to share another collab of German and Austrian #TTP registries. Important implication for managing acute #TTP. Revisiting clinical response and refractoriness in immune thrombotic thrombocytopenic purpura ashpublications.org/blood/ar…
Linus Alexander Völker retweeted
I usually think twice before posting preprints. But this time it’s different.
MEDA-PKD is the essence of our work over more than a decade — and, to me, one of the most meaningful contributions I’ve been able to make to biomedical research.
🧵
Refractory #iTTP in the #caplacizumab era is exceedingly rare and oftentimes related to secondary factors: Revisiting Clinical Response and Refractoriness in Immune Thrombotic Thrombocytopenic Purpura ashpublications.org/blood/ar…
Linus Alexander Völker retweeted
Large multicenter retrospective analysis indicating that the incorporation of caplacizumab into treatment of immune TTP in the ICU improves the ICU survival. Overall ICU survival was high.
doi.org/10.1002/ajh.70125
@Ralph_Wendt @LinusAlexanderV @oncologne @UKKoeln
Linus Alexander Völker retweeted
Obtaining a thorough family history is so important in kidney disease....but often more difficult than expected in clinical practice...
10 tips on how to take a proper family history in CKD patient care url: academic.oup.com/ckj/article…
Linus Alexander Völker retweeted
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🚨 Big news from our Genes&Kidney Working Group at the @ERAkidney
We just released a consensus statement in Nephrology Dialysis Transplantation aiming to bring us closer to precision medicine in CKD. 🧬🩺
🧵 THREAD 👇
🚨 The Capla1000+ project published!
Early use of caplacizumab significantly reduces mortality and time to response.
💥 3-mo survival: 98.5% vs. 94% (controls)
🩸 Bleeding in 2.4%, mostly elderly
💡 Age key mortality factor
🔗tinyurl.com/fpx8uuvp
#TTP #Caplacizumab
Linus Alexander Völker retweeted
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TPE-FREE MANAGEMENT OF IMMUNE TTP (iTTP)
Retrospective study from Austria and Germany
ADAMTS13 activity at baseline <10% in all patients
Treatment group (TPE-free): 42 acute iTTP episodes in 41 patients received TPE-free management with caplacizumab + steroids +/- Ritux
Linus Alexander Völker retweeted
Free scientific illustrations for biologists! 😍
@NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations!
all freely available in the public domain.
Retweet and spread the message!
bioart.niaid.nih.gov/
Linus Alexander Völker retweeted
Made it to the LBCT session
And it is a hyponatremia trial!
#KidneyWk
Linus Alexander Völker retweeted
Management of immune thrombotic thrombocytopenic purpura without therapeutic plasma exchange. This is a real change in treatment of our iTTP patients! Congratulations to the authors for this nice paper ashpublications.org/blood/ar…
iTTP treatment w/o plasma exchange -final print version now out! Exploring novel treatment paradigms and alleviating treatment burden with the support of great international colleagues!
doi.org/10.1182/blood.202302…
What’s new in nephrotic syndrome? An Updated Comprehensive Review on Diseases Associated with Nephrotic Syndromes - thanks to all coauthors and great collab w/@Ralph_Wendt mdpi.com/2227-9059/12/10/225…
Linus Alexander Völker retweeted
Wie übernehmen wir Patienten unter laufender CPR im Schockraum? Wie lagern wir um, wechseln das Device, kommunizieren etc? Solche (+ viele andere) Situationen üben wir in unseren interdisziplinären SR-Trainings im Schwerpunkt KAN der Uniklinik Köln #ukk
Linus Alexander Völker retweeted
🧵Thread on frontline caplacizumab and plasma exchange in TTP🚨
With advancing care for immune thrombotic thrombocytopenic purpura (iTTP), let’s discuss frontline caplacizumab (capla) and the future for therapeutic plasma exchange (TPE) ⤵️
#hemetwitter #TTP #caplacizumab
1/22
Our comment on Recombinant ADAMTS13 for Immune Thrombotic Thrombocytopenic Purpura | New England Journal of Medicine nejm.org/doi/full/10.1056/NE…
@Ralph_Wendt and Paul Brinkkötter
Linus Alexander Völker retweeted
Food is medicine...and what we eat governs outcome in many types of diseases (if not all). This includes solid organ transplantation.
Fueling the success of transplantation through nutrition:... : Current Opinion in Organ Transplantation journals.lww.com/co-transpla…
One of the most pressing questions in the era of caplacizumab is if iTTP can be managed without plasma exchange! Check out our paper addressing this question: Management of Immune Thrombotic Thrombocytopenic Purpura without Therapeutic Plasma Exchange ashpublications.org/blood/ar…
Mein Gedanken sind bei der Familie des Opfers. Ich fahre täglich mit dem Fahrrad an dieser Stelle entlang. Ein Blick auf die Verkehrsführung und das unkontrollierte Parken hier macht jedem sofort klar, wie egal der Stadt Köln die Sicherheit der Fahrradfahrer und Fußgänger ist.
Eine Radfahrerin war am Dienstag von einem Lkw erfasst worden. 2023 zählte die Kölner Polizei 2065 Unfälle, an denen Radfahrerinnen oder Radfahrer beteiligt waren. ksta.de/koeln/lindenthal/kle…
Linus Alexander Völker retweeted
Ein Fall, der uns letztes Jahr im konservativen Schockraum der #ukk beschäftigt hat: Atemwegsschwellung nach Trinken von Rohrreiniger | springermedizin.de
Danke an alle Co-Autoren, stellvertretend @chueser3 und @BlomeyerRalf springermedizin.de/veraetzun…