@LindstromLab

Studying how organs form & making artificial kidneys. Group leader at the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research.

lindstromlab.usc.edu
Joined February 2020
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  • Following138
  • Followers284
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Organoids, Stem Cells, and Spatial Transcriptomics! Looking forward to building this with @GiorgiaQuadrato @MarianiLabUSC and @USCStemCell. Thanks to @CIRMnews and @KeckMedicineUSC for all the support! Job adverts going out soon!!
USC Stem Cell@USCStemCell
11 Mar 2024
To democratize access to lab-grown organ-like structures known as organoids and other advanced stem cell and transcriptomic technologies, @USCStemCell will launch the CIRM ASCEND Center. @CIRMnews stemcell.keck.usc.edu/3-95-m…

$3.95 million CIRM grant establishes USC ASCEND Center to make stem cell-derived organ models...

To democratize access to lab-grown organ-like structures known as organoids and other advanced stem cell and transcriptomic technologies, USC will launch the CIRM ASCEND Center, dedicated to “Advan...

stemcell.keck.usc.edu
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Synthetic Organizers Aid Creation of Reproducible Kidney Organoids from Stem Cells Synthetic organizers provide a way to control formation of #kidneyorganoids as more reliable models for studying disease, evaluating potential therapies @LindstromLab @USC hubs.li/Q04nBGTy0

Synthetic Organizers Aid Creation of Reproducible Kidney Organoids from Stem Cells

Synthetic organizers provide a way to control formation of kidney organoids as more reliable models for studying disease and evaluating potential therapies.

genengnews.com
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Kidney cells from stem cells. Yep, it's happening. Nils Lindström, PhD, of the @LindstromLab at @USCStemCell explains the process of turning stem cells into organoids, a pathway to identifying new treatments for kidney disease.
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Well done to MaryAnne Achieng who has made microscopy of organoids an artform.
Nils Lindstrom@LindstromLab
6 Apr 2025
How do you break symmetry along a cell planar axis? Of course WNT/BMP/FGF/NOTCH compete and talk. Each nephron is like an embryo patterning along its AP axis. @LindstromLab @USCStemCell doi.org/10.1101/2025.03.29.6…
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Nils Lindstrom retweeted
Nils Lindstrom@LindstromLab
6 Apr 2025
How do you break symmetry along a cell planar axis? Of course WNT/BMP/FGF/NOTCH compete and talk. Each nephron is like an embryo patterning along its AP axis. @LindstromLab @USCStemCell doi.org/10.1101/2025.03.29.6…
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How do you break symmetry along a cell planar axis? Of course WNT/BMP/FGF/NOTCH compete and talk. Each nephron is like an embryo patterning along its AP axis. @LindstromLab @USCStemCell doi.org/10.1101/2025.03.29.6…
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Great to have the chance to discuss the future of kidney organoid technologies and the basis of kidney development & function with Jess @JMVanslambrouck Looking forward to more collaborations and insights to make next generation stem cell derived kidney models!
Jessica M Vanslambrouck@JMVanslambrouck
29 Jan 2025
Pleased to be sharing this chapter written with Nils @LindstromLab for Current Topics in Developmental Biology! Here we dive into how #nephrons establish proximal-distal patterning during #KidneyDevelopment & what this means for #StemCell-derived nephrons: authors.elsevier.com/a/1kWLp…
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Pleased to be sharing this chapter written with Nils @LindstromLab for Current Topics in Developmental Biology! Here we dive into how #nephrons establish proximal-distal patterning during #KidneyDevelopment & what this means for #StemCell-derived nephrons: authors.elsevier.com/a/1kWLp…
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Check out Mark Corkins’ collaborative preprint with @AdRoMora from our lab and MaryAnne Achieng from @LindstromLab using comparative single-cell sequencing and in situ to create this beautiful spatial model of the developing adult frog kidney! biorxiv.org/content/10.1101/…
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Nils Lindstrom retweeted
Crump Lab@CrumpLab
9 Jan 2025
The outer ear is a mammalian innovation but where did it come from? In our study in @Nature, @MathiThiru95 and colleagues find that the outer ear arose from modification of an ancestral gill program first originating in marine invertebrates. nature.com/articles/s41586-0… 1/n
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Such a great collaboration with @LeonardoMorsut and his team - am now certain that the way forward is through collaborations like these where devbio and synbio co-develop concepts. #wewillbuildakidney
Leonardo Morsut@LeonardoMorsut
13 Dec 2024
Replying to @LeonardoMorsut
tldr: we identify a new organizer activity in vivo in human developing kidney, noticed the lack of said organizing activity in kidney organoids and reconstituted the organizer action in vitro via synthetic organizers - longer thread on bluesky! @LindstromLab
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tldr: we identify a new organizer activity in vivo in human developing kidney, noticed the lack of said organizing activity in kidney organoids and reconstituted the organizer action in vitro via synthetic organizers - longer thread on bluesky! @LindstromLab
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USC Stem Cell@USCStemCell
19 Nov 2024
Genes aren’t the sole driver instructing cells to build multicellular structures. In a paper in @NatureComms, @USCStemCell scientist @LeonardoMorsut and @Caltech computational biologist Matt Thomson characterize the influence of cell density. stemcell.keck.usc.edu/exerti…
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I am excited to share our work discovering neuro-endothelial cells (NECs) - a subtype of #endothelial cells that regulate #brain and #kidney blood flow and #immune balance - now available online! Movie: NECs (green) in the mouse motor cortex #vasculature. biorxiv.org/content/10.1101/…
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Crump Lab@CrumpLab
26 Aug 2024
Replying to @Dev_journal @MarcellaBirtele
For any neuroscience departments looking for junior faculty Marcella would be a terrific hire.
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Nils Lindstrom retweeted
USC Stem Cell@USCStemCell
8 Aug 2024
How similar is kidney development in humans and in lab mice that form the foundation of basic medical research? In a new study published in @Dev_Cell, @USCStemCell scientists probe this question. @AndyMcMahonLab @LindstromLab @KeckSchool_USC stemcell.keck.usc.edu/study-…
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USC Stem Cell@USCStemCell
16 May 2024
We have two 1-year positions with a 1-year renewal option available for clinical trainees interested in conducting research related to stem cell biology and/or regenerative medicine in one of the leading labs @USCStemCell. @KeckSchool_USC stemcell.keck.usc.edu/2024-c…
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Nils Lindstrom retweeted
USC Stem Cell@USCStemCell
30 Apr 2024
A new @USCStemCell study, led by Zhongwei Li's Lab (@LiLab_Kidney), introduces a new and improved way to grow the cells that give rise to the kidney’s filtration system. @AndyMcMahonLab @LindstromLab @ukrocharity @CellPressNews @NIH_CommonFund stemcell.keck.usc.edu/usc-le…

USC-led study introduces a new and improved way to grow the cells that give rise to the kidney’s...

In a new study published in Cell Stem Cell, USC scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney’s filtration system, the...

stemcell.keck.usc.edu
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Congratulations to all on this milestone paper from Zhongwei Li’s group! Self renewing nephron progenitors in a dish opens exciting avenues for kidney research!! authors.elsevier.com/c/1j0HC… @USCStemCell @LiLab_Kidney
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Celebrating #WorldKidneyDay with @ukrocharity and Zhongwei Li’s lab @USCStemCell and @KeckSchool_USC. @LiLab_Kidney and colleagues @AndyMcMahonLab, @LindstromLab and @JPetiPeterdi are progressing on generating a transplantable kidney from human stem cells to replace dialysis.
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