@LevKats

Biologist interested in epigenetics, stem cells and cancer

 Melbourne, Victoria
petermac.org/research/labs/lev-kats
Joined December 2014
  • Tweets126
  • Following339
  • Followers433
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Menin regulates essential cell identity circuits in multiple myeloma. Menin inhibitors are really effective against pre-clinical myeloma models and can be combined with existing and emerging myeloma drugs. Check out our preprint biorxiv.org/content/10.64898…

Menin regulates oncogenic cell identity transcriptional networks in multiple myeloma

Multiple myeloma (MM) is a heterogenous cancer that remains mostly incurable. A unifying feature of MM cells is a highly interconnected network of transcription factors and co-factors that coordinate...

biorxiv.org
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Heme biosynthesis is a really fascinating pathway. We think targeting the enzymes that make heme is a really promising strategy for AML. Check out our paper online today @PeterMacCC @PeterMacRes @BloodCancerUtd @CellPressNews cell.com/cell/fulltext/S0092…

Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia

Reduced levels of the essential metabolite heme are a common feature of acute myeloid leukemia, and consequently, leukemic cells are highly sensitive to inhibition of de novo heme synthesis. Blockade...

cell.com
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Heme is a fascinating molecule and regulates many properties of cancer cells. Here we uncovered a connection between heme biosynthesis and copper homeostasis among other pathways in AML. Check out our latest preprint @PeterMacCC @PeterMacRes biorxiv.org/cgi/content/shor…
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Get on board and get your abstracts in!
ISEH@ISEHSociety12 Feb 2024
Join the Junior Faculty Committee as they host the first online Mini Symposium on 27 March! The event will include keynote presentations and short talks selected from a call for abstracts. Submit an abstract by 1 March and register today❗ Learn more: iseh.org/2024MiniSymposium
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This event is live and interactive, tune in and have your questions ready!
ISEH@ISEHSociety5 Feb 2024
🚨 Last call to sign up to join tomorrow's live webinar hosted by the Junior Faculty Committee featuring @goodell_lab and @johnstonericky. Register for free today! iseh.org/ISEHWebinars
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Lev Kats retweeted
ISEH@ISEHSociety2 Feb 2024
❗ There are only a few days left to sign up to join the 6 February live webinar hosted by the Junior Faculty Committee. Register for free today! iseh.org/ISEHWebinars
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Lev Kats retweeted
ISEH@ISEHSociety9 Jan 2024
Join the ISEH Junior Faculty Committee for their February webinar! This live webinar on 6 February will feature talks from Profs. Peggy Goodell and Ricky Johnstone as they discuss key leadership skills for your academic career. Register for free today! iseh.org/ISEHWebinars
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Get on board this week, the line up is looking fantastic @NDLR_conference
NDLR Conference@NDLR_conference8 Jan 2024
Don’t delay your registration - early bird rates close in a few days!
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We are hiring! Looking for a postdoc interested in epigenetics and blood cancers. Check out our add. Please RT careers.vic.gov.au/job/postd…
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As always, @NDLR_conference is going to be a really great meeting!
NDLR Conference@NDLR_conference26 Sep 2023
Interested in precision medicine? Prof Tim Hughes added to the line up!
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In case you missed it @landau_lab is coming to @NDLR_conference
NDLR Conference@NDLR_conference20 Sep 2023
Over the next few weeks we are highlighting our invited speakers. Stay tuned and check out our website for the latest announcements.
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Lev Kats retweeted
omer@gilan_omer7 Sep 2023
Hello, super happy to share my latest work with @MAF_Dawson where we have developed an approach that couples CRISPR screens with a direct chromatin-based readout, named CRISPR-ChIP. @NatureSMB Hope you like it. Summary below nature.com/articles/s41594-0…
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Cool new dual PI3K/BET inhibitor from Jake Shortt and co. Check out the paper pnas.org/doi/abs/10.1073/pna…
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Start thinking about your abstracts!
NDLR Conference@NDLR_conference13 Aug 2023
Abstracts are now open! Additional speakers announced soon. Check out our website
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Want to know what IDH mutations do in AML cells? Check out this review that Emily Gruber and I wrote ⁦@PPPublishing⁩ ⁦@BiochemSoc⁩ ⁦@PeterMacRes⁩ ⁦@PeterMacCC⁩ portlandpress.com/biochemsoc…
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Meeting website has gone live. Abstract submissions opening in August. Start planning!!
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The Barrie Dalgleish Research Centre for Myeloma and Related Blood Cancers was today established at Peter Mac via a generous $5M (plus $10M on milestones) bequest from Dr Barrie Dalgleish, and trustees of his estate. @maxVmor @JohnstoneRicky MORE: petermac.org/news/new-blood-…
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Really excited about hearing about some great science at #acmm
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We are looking forward to training an enthusiastic and adventurous early career scientist - come and work with @DaneVass and me in @TheDawsonLab - we promise it will be an amazing adventure
Dane Vassiliadis@DaneVass29 Nov 2022
Replying to @TheDawsonLab
@TheDawsonLab is hiring!!! Applications are now open for a wet-lab scientist to work closely with me on a range of cutting-edge projects at the intersection of #singlecell #epigenetics and #immunooncology! Apply at link below or send me a DM for more info. careers.petermac.org/job-inv…
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Proud to present my latest work with @MAF_Dawson investigating how transcription factors and core promoters influence the mechanisms of transcription biorxiv.org/content/10.1101/… Results described below 👇🧵
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