Join the GKC Advocacy Network! The fight for smart, science-backed botanical regulation is happening right now, and consumer voices are our strongest asset. We need you on our email list to help us protect the natural plant and ban dangerous lab-made synthetics. Here is what you need to do: 1️⃣ Sign Up: Use the link to join our official grassroots advocacy list. 2️⃣ Include Your State: This is critical! By providing your state, we can send you localized action alerts exactly when a bill or hearing is happening in your specific legislature. 3️⃣ Include Your Name: Let us know who is standing with us on the frontlines of botanical policy. 4️⃣ Take Action: Use our streamlined tools to message your lawmakers directly when it matters most. globalkratomcoalition.org/si… ⚠️ Compliance Notice: This account is operated by a registered advocacy non-profit organization dedicated strictly to public health education, consumer safety, and evidence-based regulatory frameworks. We do not engage in the sale, production, or promotion of commercial products. This content is shared strictly for educational and public policy comparison purposes in full accordance with platform distribution terms.

Standing with Oxford Police on the most recent statement on the Ole Miss Investigation: Differentiating Botanicals from Illicit Synthetics: The Global Kratom Coalition strongly supports the Oxford Police Department and Lafayette County Metro Narcotics in their most recent accurate assessment of the recent tragedies at Ole Miss. Local investigators have rightly emphasized the critical line between traditional botanical kratom leaf and illegal concentrated synthetic opioid products. The evidence collected in Oxford centered on "Smax" pressed tablets containing concentrated synthetic alkaloids —not unadulterated botanical leaf. The Path Forward: Acknowledge the Evidence and await finalized toxicology rather than further speculation. Follow the Federal Lead: Align state regulatory frameworks with the DEA's emergency scheduling of novel synthetics, including mitragynine pseudoindoxyl, MGM-15, and the pending scheduling of concentrated synthetic 7-OH. Target the Harm: Give law enforcement the tools needed to enforce the Federal and State regulations that currently exist to remove dangerous synthetics from the market. By supporting law enforcement's call to differentiate between plants and pills, lawmakers can close loopholes on dangerous synthetic derivatives while protecting responsible adult access to the natural leaf. Read the full analysis: globalkratomcoalition.org/ol…

Fact-Checking the Liver Conversion Myth: Why Natural Leaf is Not Synthetic 7-OH Different factions of the debate are utilizing a talking point claiming that a ‘20% liver conversion rate’ makes natural leaf kratom just as dangerous as concentrated synthetic 7-OH products. A technical brief from the Kratom Consumer Advisory Council (KCAC) shows that this claim misrepresents real-world pharmacology: The Real Math: The actual conversion rate of mitragynine to NATURAL 7-OH in the body sits between 1.25% and 5%. At peak conversion, only about 0.8 mg of natural 7-OH is in the blood from a +- a 4 gram serving of leaf. Natural leaf contains an "entourage effect" of a more than 50 biologically active alkaloids and the high fiber content in the leaf. Furthermore, the presence of mitragynine interferes with natural 7-OH's ability to stimulate opioid receptors. Synthetic 7-OH products contain no such entourage effect. No Respiratory Depression: Animal studies show mitragynine does not cause dose-dependent reductions in breathing. Isolated synthetic 7-OH, however, causes dose-dependent respiratory depression that approximates morphine's effects - this is not seen with the consumption of leaf. This clear scientific boundary is exactly why the FDA, HHS, and AMA recommend making concentrated synthetic 7-OH products Schedule I, while finding a clear difference in the risk profiles for natural leaf kratom products. Get the facts and read the full data breakdown: globalkratomcoalition.org/s/… Please share and like to spread awareness.

U.S. Drug Czar Sara Carter recently stated on Fox News that the real public health threat is synthetic alkaloids, not the natural kratom plant. She highlighted that lab-made compounds are being deceptively sold as "natural" in gas stations, causing consumers to become violently ill and hospitalized. This is exactly why the DEA & DOJ took emergency action on August 26. We must ban synthetics and protect the natural leaf! globalkratomcoalition.org