
Part of @NickPowellLab at Imperial College London. Researching the pathology of perianal fistulizing disease and small molecule inhibition IBD.
London, England
Joined November 2017
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Laura Constable retweeted
If you don’t want five more years of Tory chaos, then you have to vote Labour today.

ALT Graphic with pictures of Tory leaders past and present, Tory cabinet members past and present, and Tory MPs past and present, with the copy: 7,443,360 minutes, 124056 hours, 5169 days, 738 weeks, 170 months, 14 years. One chance for change. Vote Labour Thursday 4 July. Remember to bring photo ID.
Laura Constable retweeted
Another BSI done and another talk at the conference smashed showing our work on CTLA-4 expressing ILCs from the @NickPowellLab and Lord lab! Really enjoyed this one. Thank you to the BSI and @Hepworth_Lab and @GutOrganoid for inviting me to speak in the session! #Bsi23
Laura Constable retweeted
Let’s talk cytokinish! 🤯
Dictionary of immune responses to cytokines at single-cell resolution | Nature
Outstanding systems Immunology work by Nir Hacohen lab! nature.com/articles/s41586-0…
👏🏻👏🏻👏🏻
Well done to ex-PowellLab member @Ellie_Alberts for her BSI Bright Sparks talk
#bsi
Laura Constable retweeted
Our recent research reveals that IBD patients treated with infliximab and tofacitinib display reduced antibody responses to influenza vaccine. Continuous vaccination over two years markedly improves antibody responses compared to a one-time vaccination.
doi.org/10.1093/ecco-jcc/jja…
Laura Constable retweeted
Exciting research from @ImperialMDR reveals targeting IFNγ-producing immune cells could reverse CPI-colitis in #cancer patients, promising improved outcomes. 🧬🔬
Published in @NatureComms, this study offers a potential breakthrough in treatment.👇
imperial.ac.uk/news/248813/u…
Laura Constable retweeted
We are hiring to our group @ImperialMDR❗️
Are you interested in #PrecisionMedicine #IBD #Multiomics?
We have an exciting postdoc job for 12 months as a start (can be renewed subject to funding)
✅Great team
✅Training
✅Access to unique resources
tinyurl.com/PrecMedIBD
Pls RP
Laura Constable retweeted
So proud to present this huge amount of work on developing and characterising an in vivo model of immune checkpoint induced colitis published in @NatureComms . Thank you to everyone who contributed to the paper and especially to the @NickPowellLab
nature.com/articles/s41467-0…
Laura Constable retweeted
Congratulations Jon, and a big thank you to our co-authors and our collaborators. 🙏🙏🙏♥️♥️♥️
So proud to present this huge amount of work on developing and characterising an in vivo model of immune checkpoint induced colitis published in @NatureComms . Thank you to everyone who contributed to the paper and especially to the @NickPowellLab
nature.com/articles/s41467-0…
Laura Constable retweeted
Calling post-docs: Fancy coming to @Powelllab @Imperial to work on single cell and spatial transcriptomics in IBD and checkpoint colitis?
👇👇👇👇👇👇
imperial.ac.uk/jobs/descript…
Laura Constable retweeted
We are pleased to congratulate and present Dr James Alexander with the @BSGTrainees Young Gastro’ of the Year Prize at #BSGLIVE23! 👏🏻
Huge congratulations to James! Well deserved! 🥳👏🏻
We are delighted and proud to see our brilliant friend and colleague Dr James Alexander awarded the @BSGTrainees Young Gastroenterologist of the Year award at the @BritSocGastro conference today 🥳🤩 @ImperialMDR @ImperialBRC @NickPowellLab @ImperialPeople
Laura Constable retweeted
Countdown to BSG LIVE '23 and the GONDOMAR meeting. We hope to see you there! Get involved with the discussion and come meet team 💬🧠👀🎯 @ibdseb @NickPowellLab @DrAilsaHart @anderson_carl @philtozer1 @ibd_jess @AmyIBD @alisontalbot72 @EmmaIBDhull @IBDLola #bsglive23 #gondomar
Laura Constable retweeted
On World #IBD Day, we are excited to announce a new grant from @HelmsleyTrust centring on unravelling the immunopathology of perianal fistulising Crohn's disease. #worldibdday2023
Laura Constable retweeted
🙏 @HelmsleyTrust for supporting this important work in collaboration with @ibdseb @DrAilsaHart @philtozer1. Fistulas are a major problem for patients with Crohn’s disease and as a research community we must come together to sort it out.
On World #IBD Day, we are excited to announce a new grant from @HelmsleyTrust centring on unravelling the immunopathology of perianal fistulising Crohn's disease. #worldibdday2023
Brilliant Staff around talk from @ImperialMDR James Alexander! @NickPowellLab
Laura Constable retweeted
Excited to present @clarityibd results in #ECCO23! The venue in Copenhagen is super cool! Thanks for the amazing team efforts that created an unforgettable experience for me! @NickPowellLab @clarityibd @tariqahmadIBD @Y_ECCO_IBD
Check out @LancetGastroHep
thelancet.com/journals/langa…
Laura Constable retweeted
Aamir Saifuddin (@aamirs28) from @NickPowellLab presents a joint work #ECCO23 in which TREM1 and OSM co-expressed transcript modules are highlighted as potential predictors for drug response in #IBD. Single-cell analysis by @Matt_Madgwick from our group.
Laura Constable retweeted
Domenico Cosetto @NickPowellLab presents #ECCO23 a transcriptional atlas and assessment of #iBD mouse models and patient data to map details of inflammation. With @DrJonLo
Laura Constable retweeted
Zhigang Liu presents data from @clarityibd on neutralising Ab potency against SARS-CoV-2 wild type and omicron variants in pts w/ #IBD treated w/ infliximab or vedolizumab after 3 doses of SARS-CoV-2 vaccine; more here: thelancet.com/journals/langa… #GITwitter #ECCO2023 #ecco23



























