Structural biologist specializing in host-pathogen interactions
Joined June 2020
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- Followers398
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Daniel Wrapp retweeted
Can we leverage recent developments in machine-learning & protein design to tackle previously intractable challenges?
The answer is yes and we show it in this study led by the one and only @Dr_MattMcCallum
@HHMINEWS
@UWBiochemistry
1/9
biorxiv.org/content/10.1101/…
Daniel Wrapp retweeted
Check out our pre-print describing a CCHFV glycoprotein complex in the pre-fusion conformation! We used several engineering tricks to design our final construct, GP38-GnH-DS-Gc. Great collaborative effort, led by graduate student @Eliza4Science! biorxiv.org/cgi/content/shor…
Daniel Wrapp retweeted
My group at @ISTAustria is recruiting a lab manager/research technician to join when we start in July! If you're passionate about science and thrive in a dynamic environment, apply here: ista.ac.at/en/job/?title=Res… #ResearchJobs #LabManagement #ScienceCareers
Daniel Wrapp retweeted
Excited to share the pre-print describing our efforts to stabilize the HCMV gB ectodomain in a prefusion-like conformation. We and others have now routinely stabilized class I viral fusion proteins, but class III viral fusogens have been more difficult.
Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation biorxiv.org/cgi/content/shor… #bioRxiv
Daniel Wrapp retweeted
My Department (Biochemistry, Microbiology and Bioinformatics @ Université Laval) has 2!! tenure track positions open: one in viral ecology and one in microbial functional genomics. Awesome place to start your new lab and wonderful colleagues! 😉 Get in touch if interested. 🦠🤓
Daniel Wrapp retweeted
Delighted to have my 1st first-author paper @CellReports!
High-res site Ø and V complexes. Plus, now includes structural mapping of two non-canonical sites at the trimer interface, which are preF targets but elicit low neut mAbs. Thanks to all involved! cell.com/cell-reports/fullte…
Daniel Wrapp retweeted
Come work with us! We are hiring a lab manager to support our team investigating a broad spectrum of emerging and re-emerging viruses and developing vaccines & therapeutics!
Please RT and pass the word as widely as possible.
Daniel Wrapp retweeted
Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin dlvr.it/SWnMbv
Daniel Wrapp retweeted
The Gobeil Lab is now officially online! Check it out: gobeil-lab.github.io (and we are recruiting students - If interested in structural biology, viral evolution and protein engineering don't hesitate to reach out!)
Daniel Wrapp retweeted
Received an email from Rino Rappuoli this morning informing me, @BarneyGrahamMD and Peter Kwong of the positive phase III data for the RSV prefusion F vaccine results in older adults. It's been almost 10 years since we designed the first prefusion RSV F antigen, DS-Cav1. Amazing!
Daniel Wrapp retweeted
Our 1st “official” position is now posted!!!
Interested in coronaviruses and other pandemic threats, have previous lab tech experience, and want to join a super cool viral immunology lab at @HarvardChanSPH?
APPLY to be our RESEARCH ASSISTANT III: sjobs.brassring.com/TGnewUI/…
Daniel Wrapp retweeted
Congrats to Dr Akaash Mishra @AkaashMishra88 on his PhD thesis defense! Beautiful work on the structure and function of CCHFV glycoproteins and protective human antibodies. Next stop, Merck!
Daniel Wrapp retweeted
Efficient discovery of SARS-CoV-2-neutralizing antibodies via B cell receptor sequencing and ligand blocking go.nature.com/35O9Ali
Daniel Wrapp retweeted
We are honoring @BarneyGrahamMD with the 2022 John J. Carty Award for the Advancement of Science for pioneering new strategies in vaccine design using nanoparticle and mRNA technologies. Congratulations!
Read more: ow.ly/Nfhx50HBz3r #NASaward #biotechnology
Daniel Wrapp retweeted
Great piece on RSV vaccine and antibody development. We should soon have more interventions available to fight this virus!
RSV vaccines are closer!- an interview in @JAMA with @McLellan_Lab @RSVnews @ReSViNET jamanetwork.com/journals/jam…
Daniel Wrapp retweeted
I am looking to recruit 2 postdocs to study surface sensing (PMID:34168081), biofilm maintenance (PMID:33531388), or cdG signaling networks (PMID:29991582). Please email a cover letter, CV & 1 page project proposal to [email protected]. Pls share! @DartCF
Daniel Wrapp retweeted
I'm happy to announce that ISOLDE 1.3 is now released! To use, get your hands on ChimeraX 1.3 (release candidate 2021/12/01 or later), and install it in the usual way via Tools/More Tools. New goodies include tools for using AlphaFold models, and improved ligand handling. (1/9)
Daniel Wrapp retweeted
We're hiring postdocs. Think deep homology meets proteomics. Discover ancient biochemical systems, invent new tech, or study the structure/function/evolution of proteins in embryonic development. Please RT!
Email CV, interests, & references' contact info to [email protected]
Daniel Wrapp retweeted
New issue online! Cover depicts work from @jrmascola, @mmaryam321, @LabWrapp &co showing that vaccination with prefusion-stabilized #RSV fusion protein induces genetically and antigenically diverse antibody responses cell.com/immunity/issue?pii=…
Daniel Wrapp retweeted
New in @ScienceTM: researchers report the identification and characterization of LY-CoV555, an antibody with potent neutralizing activity against #SARSCoV2, now in clinical testing as a prospective treatment for #COVID19. fcld.ly/829yano
