Chemical Biology Laboratory @ Max-Planck-Institute for Medical Research

Joined June 2019
We continue with Richard WOMBACHER for the first oral communication ! #ChemBio2024 @reseauSCF
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What a nice way to finish the week! 🎉Our latest paper is now available online in @nchembio. 📚🔬If you missed the pre-print and like biosensors, explore our innovative approach for designing and developing chemogenetic sensors. 💡Check it out here: nature.com/articles/s41589-0….
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The MtL Lecture Series continues! 🎉 Join us on 17 May at 3 pm for an insight into the research of MtL Fellow Petra Schwille from @MPI_Biochem. Register now 👉 bit.ly/3W1z4BB
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Do you want to change the color of your biosensor on demand? Still have a large dynamic range? Check our preprint on ChemoX! More about it in the thread! (1/7) Congratulation to the team, in particular the twitterless Lars Hellweg. biorxiv.org/content/10.1101/…
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Hot off the press: @HertenDirk and @LabWombacher jointly developed a single molecule fluorescence screening assay for characterizing fluorogenic click reactions to improve bioorthogonal labelling. Credits go to Felix Hild, @PhilWerther and @KYserentant. sciencedirect.com/science/ar…
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Happy to share our pre-print about exchangeable HaloTag Ligands (xHTLs): We describe the design and characterization of fluorescent xHTLs expanding the HaloTag repertoire and finding application in 3 super-resolution microscopy techniques! (1/9) biorxiv.org/content/10.1101/…
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Natural product conference #Irsee22 about to start! Great line-up of speakers & topics in the opening session: a talented producer of new natural products, total synthesis of anti-infective drugs & a super-efficient inducer of proximity @DECHEMA @LabWombacher @ChristianJogler
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Richard Wombacher and colleagues (@LabWombacher) report a new chemical inducer of proximity based on ABA receptor dimerization by the agrochemical manipropamid. Open access: nature.com/articles/s41589-0…
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WombacherLab retweeted
I highly recommend HDyes for live-cell imaging!👍 I was very lucky to have the chance to test these new dyes, and they really outperform, with their high SNR for wash-free labeling. Congrats for the nice work!👏
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Congratulations to first authors @PhilWerther and @KYserentant and big thanks to all collaboration partners @LemkeLab @LabRadenovic Xiaogang Liu @BuckupTiago @HertenDirk. @mpi_mr_hd @IPMB_HD @UniHeidelberg
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We are glad that our fruitful collaboration with @GFantner lead to the advancements in correlative super-resolution and scanning ion-conductance microscopy imaging. We thank all collaborators! @LabWombacher @KYserentant @PhilWerther for fantastic self-blinking dyes
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Enzyme units stacked on top of each other like a spinal column – look fabulous and contains some very fascinating research! Out now @NatureMicrobiol nature.com/articles/s41564-0… mpi-bremen.de/en/Enzyme-skys… @mpi_mr_hd @BarendsThomas @MicroPhys @maxplanckpress #NXR #nitrate #anammox
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Excited to share recent @J_A_C_S using far-red silarhodamines to catalyze activation of rapid bioorthogonal chemistry in vivo. Awesome collaborators Zibo Li, Xinqiao Jia, Luke Lavis, & Colin Thorpe. Great dyes make great photocatalysts! @rhodamine110. pubs.acs.org/doi/10.1021/jac…
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Our Chemical Biology department is offering two #PhD fellowships as part of the #CONSENSE training network. The objectives for the PhD students in the group of Kai Johnsson will be the engineering of new biosensors and biomolecular nanoswitches. Apply now! mr.mpg.de/14507080/job_full_…
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Excited to share our work on a-TCO’s— a new family of trans-cyclooctenes with high reactivity and improved physiochemical properties that can be accessed as single diastereomers. Congratulations to Jess Pigga for leading this work. doi.org/10.1002/anie.2021014…
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