@LabWeekes

#HCMV #Virology #Proteomics lab based at @TheCIMR @Cambridge_Uni. Account ran by @Weekes_Mike and PhD student @Alice_F_E. #VaccinesWork

Joined May 2019
  • Tweets101
  • Following188
  • Followers630
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WeekesLab retweeted
The CIMR@TheCIMR12 Mar 2024
New insights into human cytomegalovirus from @LabWeekes authors.elsevier.com/sd/arti…
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Excited to share an EBV lytic cycle protein-protein interaction map out today: authors.elsevier.com/a/1hEje…
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Tour de force by recently graduated @virologyharvard student @YiuPty, in collaboration with Cassie Zerbe of the @LabWeekes, @HarvardMITmdphd student David Vanderwall, @EdHuttlin, and @weekes_mike. Identified common host protein nodes targeted by multiple human herpesviruses
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WeekesLab retweeted
WeekesLab@LabWeekes25 Jan 2023
We're recruiting! A Research Associate / Research Assistant position aiming to identify novel therapeutic targets against human cytomegalovirus is available for immediate appointment: jobs.cam.ac.uk/job/39220/
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Don't forget our FREE 2hr Public Session delivered via Zoom on 27th March. Included are brief talks from experts & a panel discussion where anyone can put their questions to the speakers. See full programme & register for FREE at cmv2022.org/public-session. #stopcmv #cmv2022
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Don't miss Prof. Rajiv Khann's Keynote Speech on 'Combining immunodiagnostics and immunotherapy for clinical management of CMV complications in transplant patients'. Mon 28th March #CMV2022 cmv2022.org/registration/
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On 27th March, there's a 2 hr session on Zoom for the public, with updates on CMV. It'll include brief talks from experts & a panel discussion when you can put your questions to the speakers. Registration is free, see full programme & register at cmv2022.org/public-session. #stopCMV
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Worried you can't join us for the full CMV 2021 Virtual Conference week? Then take advantage of the single day special offer, exclusively for the 'State of the Art' Keynotes on Monday 28 March. Early bird price only £50! cmv2022.org/registration/ #cmv2022 #CMV
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WeekesLab retweeted
mnhealth
@mnhealth11 Jan 2022
Today, Minnesota's Advisory Committee on Heritable and Congenital Disorders recommended the addition of congenital cytomegalovirus (cCMV) to Minnesota's newborn screening panel. (1/2)
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WeekesLab retweeted
Betty Lau@BettyCMLau5 Aug 2021
My first author paper on #HCMV #lncRNA is out in JVI Accepted Manuscripts! Human cytomegalovirus RNA2.7 is required for upregulating multiple cellular genes to promote cell motility and viral spread late in lytic infection. doi.org/10.1128/JVI.00698-21

Human Cytomegalovirus RNA2.7 Is Required for Upregulating Multiple Cellular Genes To Promote Cell...

In addition to messenger RNAs (mRNAs), the human genome encodes a large number of long noncoding RNAs (lncRNAs). Many lncRNAs that have been studied in detail are associated with broad modulation of...

journals.asm.org
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WeekesLab retweeted
Matt Butler@mjb30229 Jun 2021
FFP3 respirators provide 100% protection to NHS staff looking after patients with Covid-19 from 06:09. Excellent work @davidshukmanbbc @LabWeekes & @CUH_NHS BBC News - LIVE BBC News Channel bbc.co.uk/news/10318089
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Important work from @davejohnhughes lab up in St Andrews continuing their work digging into the molecular biology of ISG15 and how it regulates our immune response biorxiv.org/content/10.1101/…

A co-opted ISG15-USP18 binding mechanism normally reserved for deISGylation controls type I IFN...

Type I interferon (IFN) signalling induces the expression of several hundred IFN-stimulated genes that provide an unfavourable environment for viral replication. To prevent an overexuberant response...

biorxiv.org
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New preprint from the lab on the interaction of SARS-CoV2 and NK cells! We used plasma membrane proteomics (developed by @LabWeekes and Lehner labs) to determine how SARS-CoV2 manipulates proteins on the plasma membrane. biorxiv.org/content/10.1101/…

ADNKA overcomes SARS-CoV2-mediated NK cell inhibition through non-spike antibodies

SARS-CoV-2 antagonises the cellular interferon response, but whether the virus manipulates cellular immunity is unclear. An unbiased proteomic approach to determine how cell surface protein express...

biorxiv.org
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WeekesLab retweeted
Ed Huttlin@EdHuttlin2 Mar 2021
More good news about the Pfizer/BioNTech vaccine from @Weekes_Mike, @LabWeekes and colleagues! nature.com/articles/d41586-0…
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Coronavirus spread slowed by vaccines, study suggests bbc.in/3koWUoa
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New data from a study led by honorary consultant Dr @Weekes_Mike at our hospitals suggests a significant drop in the spread of #Covid19 amongst staff following vaccination. @Cambridge_Uni @wellcometrust @The_MRC @ACTcharity @NHSBT cuh.nhs.uk/news/drop-in-covi…
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Really pleased to get this paper out from the lab, it's been a long time in the making! Great collaboration with @LabWeekes and others not on twitter jci.org/articles/view/139296…
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Virologist job alert! We're recruiting at lecturer/senior lecturer level in Cardiff. Come and join me, @alanlparker, @irhumphreys, and Eddie Wang to do some great virology.... krb-sjobs.brassring.com/TGne…
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Next up @TheCIMR 2020 Research Retreat - session on #ResearchCulture incl outline of the inspirational EDI Champions Network from @LeahMary_Hunter and our new #publicengagement strategy from @jabartlet Showcasing the wonderful community that is the beating ❤️ of the institute
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I'm happy to share the formal publication of our proteomic analysis of HSV-1 infection, now out in @CellReports (doi.org/10.1016/j.celrep.202…). We use complementary mass spectrometry and biochemical techniques to probe how HSV-1 changes the host-cell proteome during infection.
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