@LabStork
Joined April 2021
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Kieran left his phone in a portaloo. These Germany fans found it, took a selfie, then handed it into the police. He has his phone back. What a country. Can we find these fans? 🏴󠁧󠁢󠁳󠁣󠁴󠁿 ❤️ 🇩🇪
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Welcome to the EMBO Workshop Autophagy across scales at Sorrento, Italy, Sept 23-27. Remember to sign up! @WAutophagy @CanCell_UiO @AutophagyNordic @AIM_autophagy @EMBO meetings.embo.org/event/24-a…

Autophagy across scales

Autophagy, a cornerstone of cellular quality control, has seen remarkable breakthroughs since the discovery of Autophagy-related genes in the 1990s. Recent advancements reveal a mechanistically plaus…

meetings.embo.org
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Next week we have the great honour of welcoming Zvulun Elazar @WeizmannScience to our @GBM_eV zoom seminar. Don't miss a fantastic lecture: April 17, 2024 - 12:30 PM CEST, Zoom Meeting ID: 813 1377 3199, Passcode: 925656 #autophagy #neurodegeneration #Cancer
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We are happy to share the publication below, which sheds light on the role of Atg1, Atg11 and Atg13 in bulk autophagy initiation. You can find the paper in the following link 👇 pubmed.ncbi.nlm.nih.gov/3823…
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#Autophagy is an essential cellular process, but how does the autophagosome assemble? Scientists reconstituted the initiation complexes in vitro and found that subunits ATG13 and ATG101 must switch between 2 conformations for assembly to occur. ow.ly/zZvb50OxhCg @FaesenLab
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Scientists @FaesenLab, @LabStork & @MeineckeLab have, for the first time, rebuilt in the lab the complex #nanomachine that starts #autophagy in the cells – and the machinery works in a completely different way than other cellular machines. @MedHHU @yourUMG mpinat.mpg.de/4456396/pr_230…

A look into the heart of cellular waste disposal

Researchers led by Alex Faesen at MPI-NAT in Göttingen visualize how a nanomachine takes care of cleaning up in the cell.

mpinat.mpg.de
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Such an honour to have presented our work yesterday in one of the epicenters of #autophagy in front of all the experts present in Sapporo #isa2022. Many thanks to the organisers (chaired by Masaaki Komatsu) for the award.
FaesenLab@FaesenLab22 Sep 2022
How can metamorphic proteins help to initiate the recycling for biomolecules in cells via autophagy at the right place and time? Read our latest work @biorxiv done @mpi_nat. A thread 🧵👇 (1/10) biorxiv.org/content/10.1101/…

Metamorphic proteins at the basis of human autophagy initiation and lipid transfer

Autophagy is a conserved intracellular degradation pathway that uses de novo double-membrane vesicle (autophagosome) formation to target a wide range of cytoplasmic material for lysosomal degradati...

biorxiv.org
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How can metamorphic proteins help to initiate the recycling for biomolecules in cells via autophagy at the right place and time? Read our latest work @biorxiv done @mpi_nat. A thread 🧵👇 (1/10) biorxiv.org/content/10.1101/…

Metamorphic proteins at the basis of human autophagy initiation and lipid transfer

Autophagy is a conserved intracellular degradation pathway that uses de novo double-membrane vesicle (autophagosome) formation to target a wide range of cytoplasmic material for lysosomal degradati...

biorxiv.org
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Monitor autophagic flux in mammalian cells easily with our new method, now out in @eLife! Pulse-labeled HaloTag reporters are processed in lysosomes, releasing proteolysis-resistant labeled Halo. Free labeled Halo amount = autophagic flux! →western/in-gel fluo/microsc./flow cyto
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Discussion over.
DW Sports@dw_sports22 Jun 2022
Sadio Mané is the biggest star ever signed by a Bundesliga side. Discuss.
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Endlich weiß ich, wieso @c_drosten die Pandemie erfunden hat. Das vollständige Video gibt es hier: youtube.com/watch?v=tPLDhVID…
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