@LabSoap

find me on bluesky https://xitter.cf/t.co/PLENPzu0Jm #sciencenotsilence #Julie_Gavard #basicresearch #tumorcells survive, adapt and remodel their environment

 Nantes, France
nbidere.wix.com/soap
Joined September 2015
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Just Published! onlinelibrary.wiley.com/doi/…

Cell Type–Specific Ferroptosis Regulatory Networks in the Bone Microenvironment: Implications for...

Overview of ferroptosis in osteoporosis (OP): physiological mechanisms (lysosomal Fe2+ release, mitochondrial ROS, and NINJ1 activation), aging-related systemic amplification and early prevention,...

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Unraveling the Dynamics of Oxytocin in Hypothalamic Neurons

Oxytocin (OT) plays an important role in regulating social behavior, and dysregulation of the oxytocinergic system leads to social impairments, such as autism spectrum disorder. Central OT release...

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Clathrins Are Involved in the Endocytosis of Host Cytosol in the Malaria Parasite

This study characterized clathrin function in hemoglobin uptake from host red blood cells via the malaria parasite's specific endocytosis machinery, cytostome. Clathrin heavy chain, clathrin light...

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Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule-dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential...

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Copper Homeostasis at the Crossroads of Cellular Metabolism, Epigenetic Regulation and Protein...

Copper homeostasis is maintained in the cell by epigenetic regulation, and various metabolic processes. Regulated copper homeostasis balances normal protein trafficking, amino acid metabolism, etc.,...

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CIN85 and CD2AP Are Novel Constituents of Dynamic Tubular Recycling Endosomes That Regulate...

In this study, we characterize tubular recycling endosomes and demonstrate that they are dynamic and undergo biogenesis upon CD98 internalization and fission over time. We identify CD2AP and CIN85...

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FGF Signaling Promotes Lysosome Biogenesis in Chondrocytes via the Mannose Phosphate Receptor...

FGF signaling regulates lysosomal homeostasis in RCS chondrocytes by inducing TFEB/TFE3 nuclear translocation and activation. This promotes the expression of lysosomal genes and mannose 6-phosphate...

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See the latest publications onlinelibrary.wiley.com/jour…. Traffic is also on BlueSky bsky.app/profile/traffic-jou…

Traffic

Traffic is a cell biology and biochemistry journal devoted to intracellular transport, covering subcellular trafficking, membrane dynamics, organelle function & more.

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Editor's selected articles of the last two years onlinelibrary.wiley.com/doi/…

Editors Choice Articles: Traffic

Traffic is a cell biology and biochemistry journal devoted to intracellular transport, covering subcellular trafficking, membrane dynamics, organelle function & more.

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From Mechanisms to Therapy: Exploring the Role of Ferroptosis in Cervical Cancer Transformation and...

This review mainly discusses the role of ferroptosis in cervical cancer from four aspects: underlying mechanisms, stage-specific sensitivity, ferroptosis-related targets and biomarkers, and clinical...

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Strain‐Dependent Immune Signaling by Small Extracellular Vesicles Derived From Trypanosoma cruzi‐...

Chagas disease, caused by Trypanosoma cruzi, remains a major treatment challenge due to variations in host immunity and parasite strains. We found that small extracellular vesicles (EVs) from...

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Spatiotemporal Analysis of Glucagon Secretory Granule Dynamics

The schematic abstract illustrates the workflow of the study. Confocal image stacks were acquired from α cells (glucagon granules) and β cells (insulin granules) labeled with ZIGIR. Single-particle...

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Virion Associated Importin Subunit Beta‐1 Augments Nuclear Import of HIV‐1 Pre‐Integration Complex

Viruses produced from CD4+ T lymphocytes exhibit significantly higher infectivity than HIV-1 viruses egressing from virus-restrictive cells like astrocytes. Importin β1, a key karyophilic protein,...

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The Role of Small Extracellular Vesicles in Tumor Development and the Prospect of Targeted Therapy

Mechanisms of sEV uptake:① Membrane fusion.② Endocytosis.③ Receptor-ligand interaction.

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Beyond the Secretory Pathway: New Insights Into Protein Release

While proteins bearing N-terminal signal or leader sequences are secreted via the ER-Golgi-plasma membrane axis of the conventional secretion pathway, many cytosolic proteins lacking signaling...

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#nocomment
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Junctional adhesion molecule C limits glioblastoma stem-like cell invasion by regulating integrin adhesion at the endothelial interface dlvr.it/TMknT7

Junctional adhesion molecule C limits glioblastoma stem-like cell invasion by regulating integrin...

Rosińska et al. reveal that GSCs rely on the JAMC adhesion molecule to anchor to endothelial surface. JAMC depletion alters GSC phenotype and signaling, promoting a more aggressive behavior in mice,...

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Happy to share this piece by @LabSoap's postdocs @LaisBFugio, @JaneJardine6, #QuentinRoux, #SaraRosinska and myself on postdoc peer meetings and co-development in @FEBSJournal. @InsermGrdOuest febs.onlinelibrary.wiley.com…

FEBS Press

‘Who in their right mind would add another meeting to an already overflowing schedule?’ This thought crossed our minds when we first discussed the idea of a postdoc peer group meeting. We are five...

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How to promote co‐development between postdocs: a case for peer group meetings - Brigliadori Fugio - The FEBS Journal - Wiley Online Library febs.onlinelibrary.wiley.com…

FEBS Press

‘Who in their right mind would add another meeting to an already overflowing schedule?’ This thought crossed our minds when we first discussed the idea of a postdoc peer group meeting. We are five...

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SOAP retweeted
SOAP@LabSoap1 Jan 2025
Waoooo !!! Thanks to @cancerscnews for highlighting our research on #glioblastoma in @CellReports @LabSoap @c_maghe @Crci2naClub @InsermGrdOuest @CNRS_dr17 @CNRSbiologie @laliguecancer - 2024 was a fantastic year with many breakthroughs in #CancerResearch
Cancer Stem Cell News
@cancerscnews31 Dec 2024
📯 The moment we've all been waiting for! 👑 Crowned first place in this year's Top Post Countdown is Dr. Julie Gavard (@LabSoap) and team at @CNRS! Their study explored MALT1 repression in #glioblastoma stem-like cells. xitter.cf/cancerscnews/status/17…
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