@LabSeale

We study thermogenic fat and we have fun doing it! Account managed by lab personnel. Opinions are our own.

 Philadelphia, PA
med.upenn.edu/sealelab/
Joined September 2019
  • Tweets36
  • Following40
  • Followers640
The Seale Lab (UPenn) retweeted
Paul Titchenell@PaulTitchenell11 Jan 2024
Excited to share our new manuscript ⁦@MolMetab⁩ This study led by ⁦@CAMBUpenn⁩ graduate student Libby Nunn explores the potential of activin type II receptor blockade to maintain muscle mass and enhance fat loss during GLP1RA in obese mice sciencedirect.com/science/ar…
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The Seale Lab (UPenn) retweeted
Seoyoung Jun@seoyoung_jun29 Aug 2023
How does embryonic #brownfat develop? Very excited to share our recent findings in @Dev_Cell on GATA6, a crucial transcription factor required for Pparg expression and #brownfat development. Thanks so much to everyone involved! #adipocyte #obesity cell.com/developmental-cell/…
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The Seale Lab (UPenn) retweeted
Penn IDOM@PennIDOM14 Mar 2023
Wonderful tribute for the late Dr. Franz Matschinsky by @KlausKaestner at #Kroc Spring Symposium
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The Seale Lab (UPenn) retweeted
Dr. Nadia Chaudhri@DrNadiaChaudhri13 Sep 2021
Now that I have 100K followers, I want to talk about #OvarianCancer. Specifically my gritty story. The goal is awareness. I hope you find this narrative informative.
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The Seale Lab (UPenn) retweeted
Penn IDOM@PennIDOM14 Jan 2020
IDOM/DRC Seminar: Jan. 14, 2020 @ 4:00 pm Student Invited Speaker - Barbara B. Kahn, M.D. “The Biology and Mechanisms of Action of a Family of Bioactive Lipids that Protect Against Type 1 and Type 2 Diabetes”
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The Seale Lab (UPenn) retweeted
Rutter Lab
@RutterLab5 Dec 2019
Proud to share our latest paper from the graduate work of the extraordinary @ClaireBensard, "Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier", in collaboration with the Thummel lab, out in @Cell_Metabolism today bit.ly/35YeeIa #MPCforLife
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The Seale Lab (UPenn) retweeted
Penn IDOM@PennIDOM27 Nov 2019
Dr. Carrie Burns an Associate Professor of Clinical Medicine @PennMedicine writes outstanding Op-Ed in @PhillyInquirer on Diabetes in Pregnancy. Check it out here - inquirer.com/health/expert-o…

I have diabetes. Can I also have a healthy pregnancy?

My 27-year-old patient, recently diagnosed with Type 1 diabetes, was worried about carrying a baby. We had a lot to talk about -- including information I hoped would allay her fears.

inquirer.com
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The Seale Lab (UPenn) retweeted
Tanentzapf Lab@TanentzapfLab12 Nov 2019
1. These are my own personal 10 commandments of peer review: I the reviewer WILL write my review in a helpful, kind, & considerate voice. I will NOT sound angry, be snarky, make derogatory comments, be rude, be dismissive, or be condescending.
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The Seale Lab (UPenn) retweeted
Jonathan Friedman@LabFriedman8 Nov 2019
The Friedman lab is ready to grow! We’re looking for a postdoc/sr research associate with an interest in mitochondria and structural/biochem approaches. We've got a great project in mind and world class facilities at UTSW! Contact by email or come find me at ASCB. Please RT!
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The Seale Lab (UPenn) retweeted
Dr. Rachel Stine@RayRayStine11 Nov 2019
Check out this great thread! Excellent resource for young scientists 😊
Kaitlin Fogg@kaitlin_fogg8 Nov 2019
I finally went through all my bookmarked tweets to compile a list of resources I want my grad students to have and wanted to (1) thank everyone who posted these resources, and (2) pay it forward and share the compiled list with all of you!
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The Seale Lab (UPenn) retweeted
Cell Metabolism@Cell_Metabolism8 Nov 2019
Adipocyte Hypoxia-Inducible Factor 2α Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism dlvr.it/RHrkHt
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The Seale Lab (UPenn) retweeted
Denis Wirtz@deniswirtz7 Nov 2019
I know it will sound insane, but we have identified 490 funding opportunities for early-career faculty. Download our ever larger and updated list of opportunities with info about eligibility, amount, deadline, etc. research.jhu.edu/rdt/funding…
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The Seale Lab (UPenn) retweeted
Dr. Rachel Stine@RayRayStine8 Nov 2019
An excellent resource from JHU, my alma mater. They have one for PhD student and early career faculty also. Lots of great opportunities!
Denis Wirtz@deniswirtz7 Nov 2019
Tell your postdocs about this funding resource from our office @JohnsHopkins: research.jhu.edu/rdt/funding… We have identified 317 different types of postdoc fellowships in engineering, clinical and life sciences, humanities, social sciences, etc.
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The Seale Lab (UPenn) retweeted
Penn IDOM@PennIDOM28 Oct 2019
Check out the latest research from @RaySoccio MD, PhD and colleagues: two types of human genetic variants affect expression of the PM20D1 gene, and PM20D1 regulatory genetic variation is associated with obesity @PNASNews pnas.org/content/early/2019/…

Natural human genetic variation determines basal and inducible expression of PM20D1, an obesity-a...

PM20D1 is a candidate thermogenic enzyme in mouse fat, with its expression cold-induced and enriched in brown versus white adipocytes. Thiazolidine...

pnas.org
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The Seale Lab (UPenn) retweeted
atul deshmukh@atul_deshmukh124 Oct 2019
First human brown and white secretome is out 📣. Discovery of novel brown fat secreted protein (batokine). Thanks to Camilla Scheele, Lone Peijs and Matthias Mann. cell.com/cell-metabolism/ful…

Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals...

Deshmukh et al. describe the human brown fat secretome and identify novel candidate batokines with potential effects on human metabolism. One such batokine is EPDR1, shown here to play a role in...

cell.com
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Global Catastrophe
JAMA
@JAMA_current24 Oct 2019
Between 2007 and 2017 diabetes entered the list of top 10 causes of death globally @IHME_UW ja.ma/2P8i5Nt
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The Seale Lab (UPenn) retweeted
Cell Metabolism@Cell_Metabolism24 Oct 2019
Zhao et al. show that in the context of obesity, partial leptin reduction restores hypothalamic leptin sensitivity and leads to reduced food intake, increased energy expenditure, and improved insulin sensitivity. dlvr.it/RGsNSS
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The Seale Lab (UPenn) retweeted
Gabor Egervari@GaborEgervari23 Oct 2019
My first postdoc paper out today in @nature. Alcohol-derived acetate is rapidly deposited onto histones in the brain, influencing gene expression and behavior. Potential implications for alcohol use disorder. @berger_lab @PennEpiInst @PennCDB nature.com/articles/s41586-0…
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The Seale Lab (UPenn) retweeted
Adrien M@micro_adrien15 Oct 2019
My colleagues and I had a hard time figuring this out! No tricks, just optic and physics :)
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The Seale Lab (UPenn) retweeted
Penn IDOM@PennIDOM15 Oct 2019
IDOM/DRC Seminar: Oct. 15 @ 4:00 pm Reuben J. Shaw, Ph.D. "AMPK and ULK1, Two Kinases Answering the Call to Restore Metabolic Homeostasis"
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