
Small young (pico) immunology lab in @SapienzaRoma. PI is Silvia Piconese. In love with regulatory T cells. (Thanks to @daisychungart for the profile pic)
Rome
Joined January 2020
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Tregs can choose between producing TNF or sensing TNFR2... and the two states are much different!
See our latest story published in @EurJImmunol
onlinelibrary.wiley.com/doi/…
In summary, TNF-TNFR2 signal sustains Tregs not through a pure autocrine mechanism. Rather, two Treg subpopulations exist that preferentially express TNFR2 or TNF, which cooperate in enforcing Treg suppression.
Journal club at the immunothrombosis lab in @SapienzaRoma
@RoychoudhuriLab
@Lucia96107702
@StefaniaBasili
My expression says it all… What a wonderful discussion we had! Thank you @kallikourdis for this full immersion in a community of outstanding immunologists
Excellent seminar on Treg physiology and biology today by @LabPico at Humanitas; great data followed by a very stimulating and interactive discussion - on innate and adaptive immunity questions!
Thank you @FabriMattei for inviting Ylenia Pacella @8yLeNia8 in this interesting workshop hosted by @istsupsan
PicoLab retweeted
SIICA Mentoring Program for Postdoc: Call 2025
Why should you apply for the SIICA Mentoring Program for Postdocs?
Check how the program helped Gianluca
Ready to take the leap? Apply!
Candidate yourself as a mentee here: bit.ly/3y0gDWg
Happy to be part of this!
📌 Gremita la sala del @CnrNanotec a #Lecce. Concluso ieri il #Workshop
“La medicina di precisione nelle malattie reumatologiche e infiammatorie croniche intestinali”
📸 la photo gallery…
#ASL_Brindisi
#ASL_Lecce
@APMARR_ITALIA
@amiciibd
@EU_Commission
@mur_gov_
Today @AlessandraPinz3 presented the results of her #PhD project at the #ECI2024 congress
Well done Alessandra 👏🏻
🔵 I'm blue da ba dee da ba di 🔵
Our Perls Prussian blue staining on the cover of @JCI_insight
insight.jci.org/9/15
Our study "Iron capture through CD71 drives perinatal and tumor-associated Treg expansion" has just been published in @JCI_insight!
insight.jci.org/articles/vie…
Our data indicate that the same metabolic route (based on #iron usage) can be both beneficial (perinatally) and detrimental (in tumor), when Tregs expand. And, through that route, Tregs may impact #ironstatus at the tissue and organismal level
This study has been conducted @SapienzaRoma by @8yLeNia8 and the #Picolab, with the invaluable support of incredible collaborators! Thanks to @ClaudioTripodo @SciumeLab @valerioiebba
and those not on X.
Nothing would be possible without the support of @AIRC_it!



















