@LabPhysiology

This is the twitter profile of @fspasqualini's Synthetic Physiology Lab at the University of Pavia. Website: https://xitter.cf/t.co/hfBKhNZZe2

Joined June 2020
  • Tweets12
  • Following23
  • Followers149
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@LabPhysiology @unipv
Francesco Pasqualini
@fspasqualini13h
Bioengineering's gift to AI isn't another algorithm. It's more life-like cell cultures to learn from. LigHTS, now out in Advanced Science, makes soft, microstructured hydrogels directly in standard 1536-well plates, every well in a single 16-min light exposure. 🧵
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@LabPhysiology @unipv
Francesco Pasqualini
@fspasqualini13h
Replying to @fspasqualini
It's built for data production. Across 100+ wells, thickness varies by less than 15% and groove pitch by about 1%. Imaging stays sharp at 100x, and 1–10 ms label-free holographic QC checks every well's substrate before it becomes training data.
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Synthetic Physiology Lab retweeted
Francesco Pasqualini
@fspasqualini4 Sep 2025
‘Proliferation’ — @LabPhysiology 's artist-in-residence @Pe3lliMartina & Alessandro “Choxee” Ciociola.  At #SUPERHOST (Cisternino): an interactive mirror that weaves your image into a golden spiral + cell microscopy. Art + science meet: from illustration to provocative parallels (cancer vs over-tourism). Info: artribune.com/mostre-evento-…
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🎨 New @LabPhysiology logo drop! Crafted by @Pe3lliMartina. Big thanks to @Kkitparker & Michael Rosnach for sparking our art‑science journey at the Harvard DBG. Process PDF attached. See it live ➡️ syntheticphysiologylab.com
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@BiophysRev & @AIP_Publishing now accept peer‑reviewed #Visuals—image‑centric articles where the artwork is the result. I lay out the vision in my editorial: doi.org/10.1063/5.0203543. Ready to publish your #SciArt?

When art and science collide

We at Biophysics Reviews (BPR) are proud to introduce “Visuals,” a new format designed to capture the essence of biophysical research through compelling imagery

pubs.aip.org
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Synthetic Physiology Lab retweeted
Francesco Pasqualini
@fspasqualini8 Jul 2025
🚀 CALIPERS v2 preprint is locked—journal submission next. Final polish, more hiPSC reference lines, and fresh light-sheet data. Still, a great collaboration led by @moisesdisante with the team @LabPhysiology and the amazing @berteroale and @florianjug group members! doi.org/10.1101/2024.12.19.6…
Francesco Pasqualini
@fspasqualini10 Jan 2025
Light sheet data coming along for this …
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Synthetic Physiology Lab retweeted
Reto Fiolka@RetoPaul16 Jun 2025
The MOSAIC reconfigurable microscope by @Eric_Betzig et al is finally out! MOSAIC integrates multiple advanced imaging techniques including light-sheet, label-free, super-resolution, and multi-photon, all equipped with adaptive optics: biorxiv.org/content/10.1101/…
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Preprints from the lab stemming from our @ERC_Research project #SYNBIO.ECM @unipv 1. Combining FUCCI with live cell phenotypic? Introducing CALIPERS
Francesco Pasqualini
@fspasqualini23 Dec 2024
1/2 pre-prints to end the year! @LabPhysiology is happy to present *CALIPERS: Cell cycle-Aware Live Imaging for Phenotyping Experiments and Regeneration Studies* led by @moisesdisante and in collaboration with the amazing @berteroale and @florianjug labs biorxiv.org/content/10.1101/…

CALIPERS: Cell cycle-aware live imaging for phenotyping experiments and regeneration studies

Measuring cell structure and function along with cell cycle progression in live cell imaging has been challenging because Fluorescence Ubiquitin Cell Cycle Indicators (FUCCI) and most phenotypic...

biorxiv.org
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2. Combining hydrogels with high throughput screening? Easy, with HYDRA!! xitter.cf/fspasqualini/status/18…
Francesco Pasqualini
@fspasqualini24 Dec 2024
And here is pre-print 2/2 before the end of the year! *HYDRA: HYdrogel Dispensing with Robotic Automation* - a scalable solution for drug testing. Great work by @eloisa_torchia, her team @LabPhysiology and the labs of @SylvainGabriele @CimettaLab and Lind biorxiv.org/content/10.1101/…

HYDRA: HYdrogel Dispensing with Robotic Automation for high throughput drug testing

The poor predictivity of traditional cell culture platforms hampers drug research and development efficiency. While organoids and organs-on-chip mitigate this problem by introducing biomimetic...

biorxiv.org
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Synthetic Physiology Lab retweeted
Francesco Pasqualini
@fspasqualini26 Jul 2021
My Synthetic Physiology Laboratory at the University of Pavia (Italy, ~30 mins from Milan) is opening an ERC-funded, two-year mechanobiology post-doctoral position. Lab link: syntheticphysiologylab.com 1/10

Synthetic Physiology Lab | University of Pavia

Official website of Synthetic Physiology Lab (SPL), the Pasqualini Lab at the University of Pavia, building instrumented cells, tissues, and computational models.

syntheticphysiologylab.com
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We are looking for an expert in traction force microscopy (TFM) to work on human induced pluripotent stem cells in our ERC-funded project SYNBIO.ECM. Ideal candidates have extensive TFM experience in their PhD, but exceptional appointments can be made for PhD or instructors.
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Synthetic Physiology Lab retweeted
Francesco Pasqualini
@fspasqualini10 Mar 2021
Equipment and people are rolling in, microscopes and cells next month --> COVID has slowed us down but hasn't beaten us! @ERC_Research lab @unipv looking for postdocs in #TFM, #Organoid, and/or #MicroscopeBuilding. DM if interested. RT appreciated.
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