@LabMelikian

Cocaine-sensitive dopamine transporters and their regulation; Relationship to DA-related neuropsychiatric disorders and addiction

 UMASS Chan Medical School
profiles.umassmed.edu/display/131975
Joined July 2019
  • Tweets83
  • Following122
  • Followers115
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Congrats @PatKearney90 on your "final" paper from the Lab! #Neuroscience #Parkinsons nature.com/articles/s41531-0…
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We are looking for a motivated postdoc to join our team studying the addictive process and circuitry! Please re-tweet or reach out with prospective candidates! #neuroscience #addiction neurojobs.sfn.org/job/38523/…
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During weekly lab meetings the people in my group present in one slide the highlights/progress of the past week. This is the best slide we’ve ever had. We laughed so much and hugged because: science is hard, it’s okay to admit it, and we are all in it together 🙂#mentalhealth
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How does addiction corrupt the brain's ability to analyze rewards? How does it affect those afflicted and their loved ones? How will research drive new treatments?
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Haley Melikian retweeted
Susanna Molas@Molas__S28 Apr 2023
📢 Please retweet: We have an opening position for a PRA! The lab is growing and we want you to be part of it! Feel free to contact if you have any questions (susanna.molas@colorado.edu)! 🧠🐭🔬🧬 jobs.colorado.edu/jobs/JobDe…
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Hooray @PatKearney90 for getting this submitted! #neuroscience #Dopamine #Parkinsonsdisease Rit2 loss in dopaminergic neurons drives a progressive Parkinsonian phenotype biorxiv.org/content/10.1101/…

Rit2 silencing in dopamine neurons drives a progressive Parkinsonian phenotype

Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease and arises from dopamine (DA) neuron death selectively in the substantia nigra pars compacta (SNc) . Rit2 is a reported...

biorxiv.org
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Congratulations @PatKearney90 for your hard work and success! First demonstration of cell autonomous mechanisms regulating the DA transporter in presynaptic terminals, and impact on behavior.#neuroscience #dopamine jbc.org/article/S0021-9258(2…

Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates...

Extracellular dopamine (DA) levels are constrained by the presynaptic DA transporter (DAT), a major psychostimulant target. Despite its necessity for DA neurotransmission, DAT regulation in situ is...

jbc.org
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Haley Melikian retweeted
Benny Sharoni@SharoniBenny15 Aug 2022
Looking forward to our show in Montreal @upstairsjazz this Saturday August 20! Come join the fun! @Montreal4Jazz @MTLMusicians #jazzmusic
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When your girl becomes the face of a company....congrats @LeyahRoses #actress #RedHeadsAreBeautiful
SHEETZ
@sheetz16 Feb 2022
Make every day fry-day! #WhyTheSheetzNot
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Great revision by @PatKearney90. Fingers crossed! Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function biorxiv.org/content/10.1101/…

Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates...

Extracellular dopamine (DA) is temporally constrained by the presynaptic DA transporter (DAT). Decades of work stemming from primarily in vitro systems support that DAT is dynamically regulated by...

biorxiv.org
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Haley Melikian retweeted
Dr. Rita@RitaFagan1 Sep 2021
Yay! It's finally out! #neuroscience #molecularpsychiatry #naturejournals
Haley Melikian@LabMelikian1 Sep 2021
Hooray @RitaFagan on publication of the final paper from your PhD work! nature.com/articles/s41380-0… #neuroscience
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Hooray @RitaFagan on publication of the final paper from your PhD work! nature.com/articles/s41380-0… #neuroscience
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Haley Melikian retweeted
Susanna Molas@Molas__S1 Sep 2021
Replying to @LabMelikian @RitaFagan
Fantastic work! Congratulations @RitaFagan and @LabMelikian !
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Too hot to hang out at commencement, but we did a private hooding at the after party-congrats @RitaFagan
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Long time coming -Bravo Patrick Kearney! Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function biorxiv.org/content/10.1101/…. #neuroscience

Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates...

Extracellular dopamine (DA) levels are tightly constrained by presynaptic reuptake mediated by the DA transporter (DAT). Despite its necessity for DA neurotransmission, DAT regulation in situ is...

biorxiv.org
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Thx!
Big news: Devan Gomez in the @matthew_hearing lab was awarded an NIH F99 award to study opioid-cannabinoid regulation of motivation during withdrawal. Congratulations, Devan!
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Haley Melikian retweeted
Jess@astrojessiem6 Jun 2021
my parent’s new neighbors said i was welcome to talk to their single 24-year-old son when i “have normal hair,” so i told them he was welcome to talk to me when he has a doctorate :) for real tho, can we stop judging people based on looks? thanks
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Here are your graduates from UMass Medical School's Graduate School of Biomedical Sciences! Congratulations to you! #UMassMedical2021 @GSBS_UMassMed
UMass Medical School Graduate School of Biomedical Sciences Class of 2021

ALT UMass Medical School Graduate School of Biomedical Sciences Class of 2021

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