We research hematological malignancies and their precursor conditions. Profile image created with https://xitter.cf/t.co/zXilbQQIN2
Joined November 2021
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Exciting work from our lab out last week in @NatureComms: Single-cell RNA sequencing defines distinct disease subtypes and reveals hypo-responsiveness to interferon in asymptomatic Waldenstrom’s Macroglobulinemia @Yoshi_konnykid @IrenemGhobrial @getz_lab @DanaFarberNews
Let's walk through what we found in our new study using single-cell RNA-seq on tumor and immune cells from pts w/ asymptomatic Waldenstrom's Macroglobulinemia - out now in @NatureComms! W/ @Yoshi_konnykid @IrenemGhobrial @gaddyg #wmsm #mmsm nature.com/articles/s41467-0… 1/
Ghobrial Lab retweeted
🎥 At #IMS2024, Elizabeth Lightbody of @DanaFarber discussed SWIFT-Seq, a novel method utilizing single-cell RNA sequencing of CTCs in patients with MGUS, smoldering #Myeloma, & newly diagnosed #MultipleMyeloma.
Watch here:
👉 ow.ly/FMKP50UgEPn 👈
#MMSM #CaGenome #HemOnc
Ghobrial Lab retweeted
Kudos to @IrenemGhobrial @LabGhobrial for the amazing work presented at #ASH24
Always pushing technology to the next level and bringing new insight in myeloma #mmsm
My favorite: the use of imaging mass cytometry to understand CRS, hematotoxicity and survival after CAR T therapy
Ghobrial Lab retweeted
Thrilled to present our award achieving abstract on longitudinal single-cell immune profiling of patients with HRSMM and RRMM receiving Teclistamab at #ASH24. Thankful to my mentor @IrenemGhobrial and everyone at Ghobrial lab for the support. @DanaFarber @ASH_hematology #mmsm
Ghobrial Lab retweeted
This Startup Raised $5.2 Million To Develop Blood Tests For Cancer #mmsm. We are excited to launch Predicta Bio for myeloma patients forbes.com/sites/jacobwendle…
Ghobrial Lab retweeted
Today, the FNIH Biomarkers Consortium announces the launch of a significant project to develop and validate blood-based biomarkers for predicting progression to multiple myeloma. This collaborative initiative brings together critical resources and stakeholders from the public sector, the private sector, and academia. By creating less invasive and more accurate prediction methods, we aim to enable earlier treatment and improve patient outcomes.
Watch to hear more about the project from investigators Irene Ghobrial, MD, Professor of Medicine, @DanaFarber, and Bruno Paiva, PhD, Co-director, Flow Cytometry Platform & Monoclonal Gammopathies Research Laboratory, @unav
Learn more at fnih.org/MMyeRisk
#FNIH #BridgesToBreakthroughs #Biomarkers #BiomarkersConstortium #MultipleMyeloma #CancerResearch
Ghobrial Lab retweeted
Agenda - IBC. Amazing group of scientists are meeting next week to discuss early detection and interception of blood cancers. Join us virtually if you can #ibc24 #mmsm @DanaFarber ibcworkshop.org/agenda/
Ghobrial Lab retweeted
In contrast to our previous study of #CHIP in #multiplemyeloma which was in a different era, we now report good outcomes even in those with #myeloma and #CHIP in the era of novel agents. Yet, there is an accelerated increase in the incidence of CHIP while on #mmsm treatment. – at Bronx, NY
Just published:
Clinical outcomes and evolution of #clonalhematopoiesis in patients with newly diagnosed #multiplemyeloma, by @tarekmd91 et al.
bit.ly/47AGsce
@IcahnMountSinai #openaccess
Ghobrial Lab retweeted
#ASH23🩸Such a great experience to finally share my IRF4 inhibitor story! Great meeting new colleagues, old friends…and you can’t beat the 🌞 in San Diego 🙌🏾! @IrenemGhobrial @JunQiLab @SiranoDhePagano
Ghobrial Lab retweeted
Stay tuned for more on this exciting work from @LabGhobrial !
Ghobrial Lab retweeted
We are excited to launch our new Centers for Early Detection and Interception. Designed for individuals with an increased risk of developing cancer, we will focus on detecting cancers sooner and stop them from developing. dana-farber.org/newsroom/new…
Ghobrial Lab retweeted
Only with @IrenemGhobrial would I ever for a moment consider it possible to pull together an entire scientific conference in 3 weeks 🤯
Inaugural Center for Early Detection and Interception of Blood Cancers Scientific Retreat was a success!
Already planning next year 😊
@ken anderson talking about endpoint for interception in blood cancers. @Lachelle_Dawn was an outstanding leader of the retreat. #center of early detection and interception of blood cancers #CEDI-BC.
Ghobrial Lab retweeted
Physician-scientist @IreneGhobrial speaks about how her multidisciplinary team works hard and fast to address health disparities in bone-marrow cancer @DanaFarber. Interview by @francesgatta go.nature.com/3pIaMAJ
Ghobrial Lab retweeted
Our study evaluating TR-FRET based serological assays is published now @CellRepMethods!
How is it done and what have we found? A thread 1/N
#FRET #Serology cell.com/cell-reports-method…
