@LabBeatty

Unofficial twitter of the Beatty Lab. Managed by his mischievous lab members. Home of the #ShitGregorySays series!

beatty-lab.org
Joined May 2020
  • Tweets370
  • Following178
  • Followers353
85Media
Jacqueline Plesset (@JPlesset) in the @LabBeatty defends her thesis tomorrow!
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Beatty Lab retweeted
Eric Topol
@EricTopol19 Apr 2024
The liver can be a path towards establishing immune tolerance for autoimmune diseases. But it also promotes immune evasion of cancer. A mechanism for this is identified here and could prove useful for directing therapy nature.com/articles/s41590-0… @NatImmunol @LabBeatty @PennMedicine

Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins

Nature Immunology - Here the authors show how the liver affects the immune response to pancreatic ductal adenocarcinoma and that cancer immunity and survival outcomes after surgery might be...

nature.com
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“We hope to provide a roadmap to overcome the barriers that prevent #immunotherapy from penetrating throughout the tumor microenvironment and attacking #cancer cells,” said Dr. Gregory Beatty, on his work to improve immunotherapy for #PancreaticCancer. spr.ly/6018Xvy68
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Kupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice ft. Stacy Thomas, @mmwatt02, @shaantichoibose, Heather Coho, Christopher Cassella, Meredith Stone, Dhruv Patel, Kelly Markowitz, Devora Delman & @LabBeatty tinyurl.com/mrytyyyz
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Here's some insight from @mmwatt02's on his latest work in @SciImmunology which found a potential approach to improve immunotherapy in #pancreaticancer. @PennCancer @LabBeatty acir.org/weekly-digests/2023…

Activating macrophages to remodel the tumor microenvironment

One of the reasons immune checkpoint blockade (ICB) may fail in solid tumors like pancreatic ductal adenocarcinoma (PDA) is a lack of T cell infiltration and extensive myeloid inflammation in the...

acir.org
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Beatty Lab retweeted
ACIR
@ACIR_org29 Nov 2023
Targeting CD40 and Dectin-1 in tumoral macrophages in pancreatic cancer. Read our digest and interview with @mmwatt02 here 👉 bit.ly/3RkQVCF  @Penn_CBIO  @LabBeatty
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Jesse Lee from the Beatty Lab defends tomorrow! @LabBeatty
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#OpenAccess in @SciImmunology from @LabBeatty @mmwatt02 Cancer immunotherapy via synergistic coactivation of myeloid receptors CD40 and Dectin-1 science.org/doi/10.1126/scii… How to co-opt the anti-tumor functions of myeloid cells in #PancreaticCancer through complementary pathways.

Cancer immunotherapy via synergistic coactivation of myeloid receptors CD40 and Dectin-1

Activation of distinct myeloid signaling pathways converges to overcome immune suppression in pancreatic cancer.

science.org
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Combining two treatments that activate myeloid cells may prove successful against tumors where conventional T cell-based immunotherapies have failed, indicates new research in mouse models of pancreatic cancer. @mmwatt02 @LabBeatty @PennMedicine 📄: scim.ag/4RU
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Cancer research makes the impossible possible: Emily Whitehead was the first child cured of cancer with therapy from Penn. She’s back as a freshman. @Penn @PennMedicine @ChildrensPhila #immunotherapy inquirer.com/health/leukemia…

Emily Whitehead was the first child cured of cancer with therapy from Penn. She’s back as a...

She was the first child treated with CAR-T, a therapy that engineers the immune system to fight cancer, at the Children's Hospital of Philadelphia in 2012.

inquirer.com
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Nice preclinical work from @LabBeatty Kupffer cells prevent #PancreaticCancer metastasis to the liver in mice nature.com/articles/s41467-0…

Kupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice

Nature Communications - The liver is the most common site of metastasis for pancreatic ductal adenocarcinoma (PDAC). Here, the authors demonstrate that β-glucan, a microbial component...

nature.com
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BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
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Beatty Lab retweeted
PanCAN
@PanCAN30 Aug 2023
PanCAN continues to be a leading force for #pancreaticcancer research with the announcement of our largest ever single-year investment in research — more than $34 million! 🔬💜 As part of that overall record-breaking investment, made possible by our generous donors, we are excited to award nine research grants. Read more about our 2023 Grantees and their work ➡️ pcan.at/yyh5y3
PanCAN Announces Record-breaking Research Investment

ALT PanCAN Announces Record-breaking Research Investment

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I finally met @Aiims1742's in person!
BiotechTV
@BiotechTV4 Jun 2023
The latest trends in pancreatic cancer research with two experts from MD Anderson. #ASCO23 biotechtv.com/post/anirban-m…

The latest trends in pancreatic cancer research with two experts from MD Anderson

Anirban Maitra and Shubham Pant from MD Anderson tell us what targets and approaches look promising in pancreatic cancer.

biotechtv.com
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Happy to share our recent publication on reprograming myeloid cells online now at @Cancer_Cell Congratulations Dr. Liu and colleagues!!! And thanks @gupta__vineet and GB-team! sciencedirect.com/science/ar… #PDAC #immunotherapy #myeloid @SitemanCenter @washupathedu @WUSTLmed
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Love this article! Thank you @PancanMonica for sharing. Phenomenal examples of mentorship through fun/humor from @LabBeatty @HingoraniLab, 2 @PanCAN grantees/advisers and all around wonderful people 💜
Monica-Amit Mishra@PancanMonica24 Apr 2023
Say what? The principal investigators who pass down wisdom through humour nature.com/articles/d41586-0… #stuffsunilsays #ShitGregorySays @arosenzweig19
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Our #OpenAccess review on #PancreaticCancer - advances & challenges is now online at @CellCellPress Many thanks to @CJHPhD @Pasca_Lab & @LyssiotisLab for all the hard work & @jiaying_tan6 for the opportunity. It’s FREE to read so share widely! cell.com/cell/fulltext/S0092…
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🚨Ecstatic to highlight new📖from #DattaLab @SylvesterCancer in @CD_AACR, led by inimitable @anna_bianchi22! We decode🔀btwn high-risk tumor genotypes (go.nature.com/3eAJTcE), cell-autonomous inflammatory programs & myeloid⬆️/T-cell⬇️ contexts in #PancreaticCancer #pancsm 🧵/1 – at Cutler, FL

Distinct mechanisms of innate and adaptive immune regulation underlie poor oncologic outcomes...

Oncogene - Distinct mechanisms of innate and adaptive immune regulation underlie poor oncologic outcomes associated with KRAS-TP53 co-alteration in pancreatic cancer

nature.com
Cancer Discovery@CD_AACR27 Mar 2023
Cell-autonomous CXCL1 Sustains Tolerogenic Circuitries and Stromal Inflammation via #Neutrophil-derived TNF in #PancreaticCancer, by @anna_bianchi22, @DrJashDatta et al. bit.ly/3lJmCZF @umiamimedicine @SylvesterCancer
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We are very proud to present our 2023 Special Issue dedicate to a holistic view of cancer! With 10 Reviews, a Perspective, and our Editorial, we lay out what we see as the future for impactful cancer research. You can read it now: cell.com/cancer-cell/issue?p…
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Neutrophilic myeloid-derived suppressor cells infiltrating #PancreaticCancer #pancsm #SBLVII  #ScienceTwitter #DattaLab @anna_bianchi22 xitter.cf/funniestvidslol/status… – at Cutler, FL
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