@LSaund11
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✨ Brand new Junior Professor @COSHeidelberg former postdoc w/ @coletrapnell. @parichylab alum dev bio | zebrafish | neural crest | single cell genomics. she/her
Heidelberg, Germany
Joined May 2012
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Join us! The Saunders lab is looking for postdocs, PhD students, and technicians to join our new lab at #COSHeidelberg 🐟🧬🔬🇪🇺
We’re studying neural crest lineage plasticity in fish with developmental genetics and single-cell genomics. For postdoc apps: tinyurl.com/2ymnhyez
Lauren Saunders retweeted
We have postdoc openings related to EMBL's new "Life in Context" program. What's unique about them? Opportunities for fieldwork, learning cutting-edge single cell genomic techniques, using non-traditional model organisms, and a focus on the effects of the environment.
And please do check out @mwdorr’s preprint which highlights how the approach can be used to study environmentally-induced phenotypic variability!
Our preprint on using single-cell sequencing to study how zebrafish embryos manage temperature stress is now online. Led by @mwdorr, with critical contributions from @lsaund11, @maddymduran, @SRsrivatsan, and David Kimelman. biorxiv.org/content/10.1101/…
I'm excited to finally share my postdoc work, co-lead with my dear friend @SRsrivatsan, establishing a framework for time-resolved, multi-scale phenotyping of whole zebrafish embryos. See Cole's thread for a semi-brief digest of our findings! 🐟🧬
Our preprint on deep phenotyping of genetic perturbations of zebrafish embryos with single-cell RNA sequencing is now online. Led by @LSaund11 and @SRsrivatsan, with David Kimelman, @CeciliaMoens, @RaibleLab and @JShendure biorxiv.org/content/10.1101/…
Thanks especially to the dream team I was fortunate enough to work with while generating and disentangling this giant pool of data!
@mwdorr @maddymduran @RaibleLab @CeciliaMoens @coletrapnell & David Kimelman
Lauren Saunders retweeted
Are you a ⭐️molecular biologist⭐️ who wants to use single cell genomics to study how climate change affects fish development? Want to live in Europe? The Dorrity lab is hiring a Lab Officer to join our growing team! 🐟🌡🧬 embl.org/jobs/position/HD021…
Lauren Saunders retweeted
Our paper on sci-Space, a spatially resolved version of sci-RNA-seq, is out today!
Led by @srsrivatsan and @mregier13, Joint work with @JShendure and @kellystevenslab. (Art by @nigelsussman)
What a fun collab with @Andrewjohnaman! We used the power of sci-RNA-seq to profile nuclei across 4 genotypes during scale development in z-fish. Andy dug deep with live imaging, and we found some exciting new stuff about the cells involved in patterning scales and pigment!
Last up, postdoc @Andrewjohnaman and @Lsaund11 in @coletrapnell lab document the diversity of skin cell types in zfish. 8/11
biorxiv.org/content/10.1101/…
Lauren Saunders retweeted
🎉 I’m starting my lab at @EMBL Heidelberg in January! 🔥🐟🔬 We'll use zebrafish to study developmental robustness in changing environments with single-cell genomics. If that interests you, stay tuned - I'll be growing my team in the near future! embl.org/groups/dorrity/
Do not skip the movies in this one - Andy's heroic imaging efforts and fish resuscitation skills allowed him to track scale development over three months!
We have a new preprint out on postdoc @andrewjohnaman’s work on scale development in zebrafish, with help from @LSaund11 and undergrad Margaret Kim. 1/12
biorxiv.org/content/10.1101/…
Lauren Saunders retweeted
Interested in single cell genomics but need help getting started? Check out the full agenda for our Single Cell Genomics Day next Friday (3/26). All talks will be live-streamed (no registration required) at satijalab.org/scgd21/
A bright spot in 2020! Congratulations!! I guess I picked a good day to do some CRISPR editing 🙌 #NobelPrize
BREAKING NEWS:
The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”
Lauren Saunders retweeted
We made some new zebrafish tools! We built and tested a new #zebrafish #transcriptome, which improved gene detection in #RNAseq, especially in #scRNAseq. Check out our new paper at @eLife: elifesciences.org/articles/5…. My 1st "real" first author paper in almost 20 years!
Lauren Saunders retweeted
After 1200 + commits, I am proud to announce that dynamo is now on PyPi. See how we leverage it to go beyond RNA velocity to velocity / acceleration vector fields which then power us to calculate the potential, curl, divergence, curvature of single cells. pypi.org/project/dynamo-rele…
ALT vector field analysis of zebrafish pigmentation: https://dynamo-release.readthedocs.io/en/latest/zebrafish.html#
Lauren Saunders retweeted
New postdoc position available in our group to study development, genetics, or evolution of adult phenotypes. We have extra $$$ after good news on 2 fellowships and 1 R01 (written w/ a postdoc to support HIS program; we have great people).
Lauren Saunders retweeted
in exciting personal news, my grad school work has been (finally) published! many thanks to @LSaund11 - an exceptional collaborator - and many other people!
pubmed.ncbi.nlm.nih.gov/3248…