@LSChapple

Senior Critical Care Dietitian, Royal Adelaide Hospital | Research Fellow, University of Adelaide

 Adelaide, South Australia
researchers.adelaide.edu.au/profile/lee-anne.chapple
Joined July 2014
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  • Followers1.4K
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A/Prof Lee-anne Chapple retweeted
Peter Nydahl@NydahlPeterJan 30
Post Intensive Care Syndrome Edited by amazing Brad Butcher! Thank you for leading many champions of ICU rehab to this outstanding achievement! cambridge.org/core/books/pos…
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A/Prof Lee-anne Chapple retweeted
Stefan Schaller
@ProfSchaller4 Nov 2025
Our international and interprofessional perspective paper on the ICUAW research agenda has been published in #ICM. Fantastic collaboration! Fulltext: rdcu.be/eOaZY
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A/Prof Lee-anne Chapple retweeted
Critical Care Nutrition@CriticalCareNu127 Oct 2025
🔥 HOT DEBATE at #lives2025 organized by The FREM section on ICU nutrition ➡️EN vs. PN:"EN first" & sPN to prevent underfeeding? ➡️Timing: How do we practically evaluate anabolic & metabolic readines ➡️Risks of Delay: What are the costs of underfeeding vs. dangers of forcing nur
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En route to beautiful Prague for the European Society of Clinical Nutrition and Metabolism Congress. Excited to share the results of our TARGET Protein Trial on Tuesday 8:30am and seeing lots of familiar faces. If we haven’t met, come say hi! 👋🏻
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Career highlight! Honoured to present @ProteinTarget with @msummo2 at @CritCareReviews in Belfast. You can read all about the trial in JAMA: jamanetwork.com/journals/jam… Or watch the full recording at: criticalcarereviews.com
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Great way to end a busy fortnight of conferences!
Critical Care Reviews@CritCareReviews14 Jun 2025
A glorious Summer's day on the Giants Causeway..... #CCR25 Faculty Day Out
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A/Prof Lee-anne Chapple retweeted
Critical Care Reviews@CritCareReviews14 Jun 2025
A glorious Summer's day on the Giants Causeway..... #CCR25 Faculty Day Out
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A/Prof Lee-anne Chapple retweeted
JAMA
@JAMA_current11 Jun 2025
Augmenting enteral protein did not improve outcomes for critically ill patients compared with standard protein levels in the intensive care setting. #CCR25 @CritCareReviews ja.ma/45jf3NI
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Replying to @ProteinTarget
@ProteinTarget results presented today at #CCR25 and published in @JAMA_current: jamanetwork.com/journals/jam… My takeaways: 🧵

Augmented Enteral Protein During Critical Illness

This randomized clinical trial examines whether augmenting enteral protein increases days alive and free from hospitalization in critically ill patients.

jamanetwork.com
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My interpretation: 1. Short-term early higher dose protein feeding does not impact outcomes in critically ill patients. 2. Caution should be taken particularly for patients with an AKI at baseline.
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3. Lower protein doses (1.2g protein/kg/day) increased to goal over the first 4 days of ICU should be considered. 4. Future work may target the time to ⬆️ protein doses, given the impact of lower protein dose on muscle mass/malnutrition, potentially guided by urea levels.
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A/Prof Lee-anne Chapple retweeted
A/Prof Emma Ridley@ICUnutrition11 Jun 2025
Meta-analysis mentioned in the @ProteinTarget editorial- shows harm in sub-group. Also shows signal for improved physical outcomes ccforum.biomedcentral.com/ar… #ccr25

The effects of higher versus lower protein delivery in critically ill patients: an updated system...

Critical Care - A recent large multicentre trial found no difference in clinical outcomes but identified a possibility of increased mortality rates in patients with acute kidney injury (AKI)...

link.springer.com
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A/Prof Lee-anne Chapple retweeted
A/Prof Emma Ridley@ICUnutrition11 Jun 2025
Seminal work by @LSChapple and team mentioned in the @ProteinTarget editorial #ccr25 Muscle Protein Synthesis after Protein Administration in Critical Illness | American Journal of Respiratory and Critical Care Medicine atsjournals.org/doi/10.1164/…

American Thoracic Society Journals

American Thoracic Society Journals

academic.oup.com
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Such a pleasure to present the @ProteinTarget trial at this incredible venue.
A/Prof Emma Ridley@ICUnutrition11 Jun 2025
Very proud to be here as part of the @ProteinTarget study team and support @LSChapple @MelbourneICU and Matt Summers @sandrapeake01 Augmented Enteral Protein During Critical Illness jamanetwork.com/journals/jam… #CCR25
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A/Prof Lee-anne Chapple retweeted
Critical Care Reviews@CritCareReviews24 May 2025
🚨 ENCOMPASS TRIAL Results at #CCR25🚨 📍 8 hospitals 👥 4032 patients 📊 Stepped-wedge cluster RCT 🎯 Tests STAR: nurse-led, telehealth care for high-risk sepsis survivors 🩺 Outcomes: 90-day readmission or death 📺 Free livestream — but it’s better in person!
Flyer for the ENCOMPASS trial results session at CCR25, investigating a nurse-led, care for high-risk sepsis survivors

ALT Flyer for the ENCOMPASS trial results session at CCR25, investigating a nurse-led, care for high-risk sepsis survivors

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Looking forward to presenting the results of @ProteinTarget in June. What a great line up for the editorial/panel!
Critical Care Reviews@CritCareReviews3 Apr 2025
#CCR25 opens with the #TARGETprotein results Is additional protein beneficial in the critically ill? Join @LSChapple @msummo2 & @MelbourneICU to find out Editorial - Angelique de Man Panel - @Zudin_P @StephptaylorCLT & Monica Taljaard Register at criticalcarereviews.com/meet…
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