@LPieperhoff

PhD Candidate @ Amsterdam UMC Department of Radiology & Nuclear Medicine Working on multimodal brain networks in Alzheimer's Disease!

 Leiden, Netherlands
orcid.org/0009-0003-9003-4588
Joined April 2023
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Polygenic risk for AD influences WM integrity both directly and via AD pathology-dependent mechanisms, suggesting that distinct biological processes are activated by AD pathology to drive white matter alterations. More on WHITE MATTER ALTERATIONS AND MRI in Hall A #ADPD2025
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Leonard Pieperhoff retweeted
Luigi Lorenzini@LuigiLorenzini125 May 2024
A nice work from our team finally out!🧠 Led by Mario Tranfa, we used multimodel selection and latent variable modelling to show the differential impact of vascular and AD-related factors on white matter microstructure. pubmed.ncbi.nlm.nih.gov/3875…

Alzheimer's Disease and Small Vessel Disease Differentially Affect White Matter Microstructure -...

Our results suggest that AD pathology and cSVD exert independent and spatially different effects on WM microstructure, supporting the role of DTI in disease monitoring and suggesting independent...

pubmed.ncbi.nlm.nih.gov
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