@LMB_Library
 Cambridge
Joined March 2012
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November Focus: Men's Health. Find your next read at the Library end of the @MRC_LMB atrium.
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NEW #LMBPublications FcRn-dependent IgG accumulation in adipose tissue unmasks obesity pathophysiology ift.tt/JKO2VP4
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NEW #LMBPublications Structural insights into a DNA polymerase reading the xeno nucleic acid HNA ift.tt/QT6GeDU
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NEW #LMBPublications Efficient circular RNA synthesis for potent rolling circle translation ift.tt/0I4oQ2b
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NEW #LMBPublications Circadian Control of Protein Synthesis ift.tt/yn31laH
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NEW #LMBPublications Modelling human brain development and disease with organoids ift.tt/JDYv3ef
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NEW #LMBPublications CRL3ARMC5 ubiquitin ligase and Integrator phosphatase form parallel mechanisms to control early stages of RNA Pol II transcription ift.tt/7DyA4x5

CRL3ARMC5 ubiquitin ligase and Integrator phosphatase form parallel mechanisms to control early...

Control of RNA polymerase II (RNA Pol II) through ubiquitylation is essential for the DNA-damage response. Here, we reveal a distinct ubiquitylation pathway in human cells, mediated by CRL3ARMC5,...

pubmed.ncbi.nlm.nih.gov
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NEW #LMBPublications Structure of the Pseudomonas aeruginosa PAO1 Type IV pilus ift.tt/iNsFIGh
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NEW #LMBPublications A framework for neural organoids, assembloids and transplantation studies ift.tt/1nq63FL

A framework for neural organoids, assembloids and transplantation studies - PubMed

As the field of neural organoids and assembloids expands, there is an emergent need for guidance and advice on designing, conducting and reporting experiments to increase the reproducibility and...

pubmed.ncbi.nlm.nih.gov
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NEW #LMBPublications A finger that gets in the way: When binding isn't just about the bound state ift.tt/vSIMtpn

A finger that gets in the way: When binding isn't just about the bound state - PubMed

In this issue of Structure, Viennet et al.1 report a study characterizing the DNA binding by a three-zinc-finger fragment from the transcription factor BCL11A, with the unusual feature that an...

pubmed.ncbi.nlm.nih.gov
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NEW #LMBPublications A cryo-electron tomography study of ciliary rootlet organization ift.tt/i6aXfUR

A cryo-electron tomography study of ciliary rootlet organization - PubMed

Ciliary rootlets are striated bundles of filaments that connect the base of cilia to internal cellular structures. Rootlets are critical for the sensory and motile functions of cilia. However, the...

pubmed.ncbi.nlm.nih.gov
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NEW #LMBPublications Structure and methyl-lysine binding selectivity of the HUSH complex subunit MPP8 ift.tt/gkBzAjE
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NEW #LMBPublications LXR regulation of adipose tissue inflammation during obesity is associated with dysregulated macrophage function ift.tt/TH2oLcB
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NEW #LMBPublications Improving macromolecular structure refinement with metal-coordination restraints ift.tt/S1MOV5Q
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NEW #LMBPublications RNA-Puzzles Round V: blind predictions of 23 RNA structures ift.tt/tWsxOzT

RNA-Puzzles Round V: blind predictions of 23 RNA structures - PubMed

RNA-Puzzles is a collective endeavor dedicated to the advancement and improvement of RNA three-dimensional structure prediction. With agreement from structural biologists, RNA structures are predic...

pubmed.ncbi.nlm.nih.gov
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NEW #LMBPublications Identification of a factor that accelerates substrate release from the signal recognition particle ift.tt/TyCYGdh

Identification of a factor that accelerates substrate release from the signal recognition particle...

The eukaryotic signal recognition particle (SRP) cotranslationally recognizes the first hydrophobic segment of nascent secretory and membrane proteins and delivers them to a receptor at the endopla...

pubmed.ncbi.nlm.nih.gov
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NEW #LMBPublications Making PI3K superfamily enzymes run faster ift.tt/1stmiTQ
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NEW #LMBPublications Macrophages and nociceptor neurons form a sentinel unit around fenestrated capillaries to defend the synovium from circulating immune challenge ift.tt/edjzpqr
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NEW #LMBPublications New players and targets in mannose 6-phosphate-dependent lysosomal sorting ift.tt/xZGVgCS

New players and targets in mannose 6-phosphate-dependent lysosomal sorting - PubMed

The Golgi apparatus serves multiple crucial roles in the cell. These roles include the addition and subsequent modification of glycans, not only to newly-made proteins arriving from the endoplasmic...

pubmed.ncbi.nlm.nih.gov
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NEW #LMBPublications A physical model for M1-mediated influenza A virus assembly ift.tt/H5C2rTN

A physical model for M1-mediated influenza A virus assembly - PubMed

Influenza A virus particles assemble at the plasma membrane of infected cells. During assembly all components of the virus come together in a coordinated manner to deform the membrane into a protru...

pubmed.ncbi.nlm.nih.gov
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NEW #LMBPublications Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease ift.tt/f4EKrsq

Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease - PubMed

The abnormal assembly of tau protein in neurons is a pathological hallmark of multiple neurodegenerative diseases, including Alzheimer's disease (AD). Assembled tau associates with extracellular...

pubmed.ncbi.nlm.nih.gov
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