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THE SCIENCE THAT ADVANCES #PATHOLOGY. Official Journal of @TheUSCAP. Editor-In-Chief: Dr. David M. Berman, M.D., Ph.D. (@virchow)
Palm Springs, CA
Joined January 2017
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Research Article Spotlight 🔬 | Exploring a dual-stream model combining deep features and cell phenotypes for the diagnosis of myeloproliferative neoplasms.
🔗 Chien et al. Read the article: buff.ly/j0qOPJi
Research Article Spotlight 🔬 | Profiling complement components in glomerular disease using tissue proteomics.
🔗 Storey et al. Read the article: buff.ly/I6PxlXl
Research Article Spotlight 🔬 | Investigating H3K18 lactylation in salivary gland epithelial cells and its association with autophagy and progression of Sjögren syndrome.
🔗 Chen et al. Read the article: buff.ly/dcrVu9y
New from Laboratory Investigation 🔬 | Molecular, histopathologic, and spatial profiling reveals shared pathogenic features of lymphatic malformations and NFATC1 activation.
🔗 Hirose et al. Read the article: buff.ly/NgRf8ra
Research Article Spotlight 🔬 | Using high-resolution spatial transcriptomics to characterize the syncytial variant of nodular sclerosis classical Hodgkin lymphoma.
🔗 Xiao et al. Read the article: buff.ly/y6lzbsU
New from Laboratory Investigation 🔬 | Optimizing DNA extraction from archival prostate biopsies to maximize DNA yield from limited tumor samples for molecular testing.
🔗 Amaral et al. Read the article: buff.ly/aEsQbcR
Research Article Spotlight 🔬 | Exploring how deep learning–based virtual staining can support general pathologists in donor kidney assessment with near-specialist diagnostic performance.
🔗 Cen et al. Read the article: buff.ly/XLEFGjC
Research Article Spotlight 🔬 | Evaluating the scoring reliability of c-Met immunohistochemical assays in lung adenocarcinoma.
🔗 Zhou et al. Read the article: buff.ly/6TluGbK
Prediction of Lymph Node Metastasis in Early Gastric Cancer Using Foundation Model Ensembles and Patch-Based Histopathological Interpretation
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Renal Pathology Society Survey of Global Renal Pathology Practice Variation in Pre-analytic and Analytic Phases
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Correspondence Spotlight 💬 | Continuing the discussion on the prognostic value of PARP1 and PARP2 copy number alterations in prostate cancer.
🔗 Segalés & Hernández-Llodrà. Read the article: buff.ly/RZit8Eg
New from Laboratory Investigation 🔬 | Histologic section thickness varies substantially from microtome settings—and AI can infer this underrecognized source of variation directly from routine H&E images.
🔗 Fujisawa et al. Read the article: laboratoryinvestigation.org/…
New from Laboratory Investigation 🔬 | Identifying two novel compound heterozygous ADAMTS17 variants associated with Weill–Marchesani syndrome 4, including a deep intronic variant shown to disrupt normal splicing.
🔗 Ku et al. Read the article: laboratoryinvestigation.org/…
Research Article Spotlight 🔬 | Validating a highly repeatable tissue proteomics approach for protein analysis in kidney transplant pathology.
🔗 Hofstraat-Boersma et al. Read the article: buff.ly/RZit8Eg
Research Article Spotlight 🔬 | Evaluating optimal preservation of formalin-fixed, paraffin-embedded samples for efficient staining in multiplex imaging.
🔗 Delarue et al. Read the article: buff.ly/Q5UDCrU
Research Article Spotlight 🔬 | Investigating how differential expression of PIWI-interacting RNAs in glioblastoma stem cells may influence tumor progression and patient survival.
🔗 Siegl et al. Read the article: buff.ly/OP8Svz1
Research Article Spotlight 🔬 | Examining the clonal progression of POLE-mutant endometrial cancer with immune evasion characteristics and metastasis.
🔗 Fan & Gao. Read the article: buff.ly/N8wcVRq
Research Article Spotlight 🔬 | Exploring Tn-MUC1 as a novel immunohistochemical marker reflecting tumor progression in breast cancer.
🔗 Shimizu et al. Read the article: buff.ly/6XrHHRd
Research Article Spotlight 🔬 | Evaluating internal positive controls and synthetic calibrators for performance assessment of estrogen receptor immunohistochemistry in breast carcinoma.
🔗 Torlakovic et al. Read the article: buff.ly/NrzE3Tp
Research Article Spotlight 🔬 | Evaluating parietal epithelial cell changes using integrin α3 immunostaining to identify potential focal segmental glomerulosclerosis.
🔗 You et al. Read the article: buff.ly/9qIVJlk