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Happy to share our latest preprint @biorxiv_immuno in which we provide a novel explanation for the phenomenon of “helpless” CD8 T cell memory
biorxiv.org/content/10.1101/…
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OBS Seminar: CD4 help for CD8+ activation
👩🔬 Verena Van Der Heide @SinaiImmunol @IcahnMountSinai @LCMVlab @ImmunityCP
👩🔬 @ValentinaVenzin @iannaconelab @SanRaffaeleMI @MyUniSR
🗓️ Thu September 4th, 11 AM EDT, 3 pm GMT, 5 pm CET
👇 Registration:
us02web.zoom.us/meeting/regi…
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CD8 memory formation with CD4 help bit.ly/4ns3TwJ @SinaiImmunol
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Compromised generation of functional CD8 T memory in absence of CD4 T cell help is not permanent but rather a transient state of delayed memory maturation
cell.com/immunity/fulltext/S…
@ImmunityCP @homann_lab
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van der Heide et al. used advanced imaging and analysis tools to study pancreatic regions from organ donors across #type1diabetes stages, including at-risk and at-onset cases.
biorxiv.org/content/10.1101/…
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Integrated histopathology of the human pancreas throughout stages of type 1 diabetes progression biorxiv.org/content/10.1101/… #biorxiv_immuno
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A paper in @Nature reports a new method for identifying the pathogens involved in sepsis cases, which could help to select optimal therapeutics. go.nature.com/3WA14hr
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Permanent lymphocyte subset elimination upon a single dose of AAV-delivered depletion antibody dissects immune control of chronic ... biorxiv.org/cgi/content/shor… #biorxiv_immuno
This work would not have been possible without the input, support, help, and commitment over the years by everyone involved @SinaiImmunol @IcahnMountSinai @scrippsresearch @EmoryVaccineCtr
Huge thank you to fantastic co-authors Bennett Davenport, Beatrice Cubitt, Vladimir Roudko @VRoudko, Daniel Choo, Etienne Humblin, Kevin Jhun, Krista Angeliadis, Travis Dawson, Glaucia Furtado, Alice Kamphorst @KamphorstAlice, Rafi Ahmed @rafiahmed_lab, Juan-Carlos de la Torre
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PD-1 blockade promotes the self-renewal of PD-1+TCF-1+ stem-like CD8 T cells in addition to their differentiation into effector cells @rafiahmed_lab
science.org/doi/full/10.1126…
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CD28 modulates the metabolism of PD-1+ CD8 T cells and is required to sustain responses during chronic antigen stimulation @KamphorstAlice @SciImmunology
science.org/doi/full/10.1126…
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📢*Announcing 2 Image Analysis Training Courses!*
1) @QuPath Training Course- October 9-11, San Diego, CA
tiny.cc/QuPathCourseFlyer
2) @QuantBioImaging Multiplex Image Analysis- October 12-13, San Diego, CA
quantitativebioimaging.com/q…
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It’s 2023, and @NIH @NIDDKgov Gateway Awards for promising young investigators contain no women. #It’sNotAPipelineProblem #RepresentationMatters #WomenInSTEM
Please join us in congratulating the newly funded 2023 NIH NIDDK Gateway Investigators that will be joining HIRN!
This initiative supports innovative projects & talented #NewInvestigators in #T1D research.
Learn more at: hirnetwork.org/consortium/ne…














