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KwunLab

@KwunLab

Human Cancer Virus Research Lab

 Hershey, PA
sites.psu.edu/kwun/
Joined December 2019
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Photo by KwunLab (@KwunLab)Photo by KwunLab (@KwunLab)Photo by KwunLab (@KwunLab)Photo by KwunLab (@KwunLab)Photo by KwunLab (@KwunLab)Photo by KwunLab (@KwunLab)
Congratulations, Dr. Pham!
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Image from KwunLab (@KwunLab)
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Penn State College of Medicine presents Commencement 2026 Awards pennstatehealthnews.org/topi…
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Polyomavirus Trojan Horse in the skin: journals.plos.org/plospathog…📷
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Check out Alex's Flash Talk (W48-7) and Poster (P22-80) at #ASV2023 "Merkel cell polyomavirus large T antigen induces cellular senescence for host growth arrest and viral genome persistence through its unique domain" Monday, June 26, 8:18 PM~10 PM Parthenon 2, Grand Hall 8
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Congratulations to Alex on receiving the Penn State Cancer Institute CRTEC Travel Award!
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Deadline extended. Cells received an increased CiteScore of 9.0. It is open to all authors.
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We welcome Suzanne Kozloski to our lab, a new MD/PhD Schreyer Honors College Summer Program rotation student !
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Congratulations to Alex Pham for being selected to receive the Graduate School Endowed Fellowship. This fellowship is intended for full-time graduate students exhibiting academic excellence. What an accomplishment!
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Congratulations on Alex's new publication!!! Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain mdpi.com/2085022 #mdpicells via @MDPIOpenAccess
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Call for Papers: Special Issue_"Viruses and Cancer: From Cellular Mechanism to Therapeutic Aspects"
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Call for Papers: Cells (Impact factor:7.666)_Special issue_"Viruses and Cancer: From Cellular Mechanism to Therapeutic Aspects" mdpi.com/si/148853 #mdpicells via @MDPIOpenAccess
Therapeutic Potential of 5′-Methylschweinfurthin G in Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma mdpi.com/1791500 #mdpiviruses via @VirusesMDPI
Therapeutic Potential of 5′-Methylschweinfurthin G in Merkel Cell Polyomavirus-Positive Merkel Cell...

Therapeutic Potential of 5′-Methylschweinfurthin G in Merkel Cell Polyomavirus-Positive Merkel Cell...

Merkel cell carcinoma (MCC) is a rare but aggressive form of skin cancer predominantly caused by the human Merkel cell polyomavirus (MCPyV). Treatment for MCC includes excision and radiotherapy of...

mdpi.com
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Cellular senescence preserves viral genome maintenance biorxiv.org/content/10.1101/…
Cellular senescence preserves viral genome maintenance

Cellular senescence preserves viral genome maintenance

Senescent cells accumulate in the host during the aging process and are associated with age-related pathogenesis, including cancer. Although persistent senescence seems to contribute to many aspects...

biorxiv.org
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Our paper "Surface charge of Merkel cell polyomavirus small T antigen determines cell transformation through allosteric FBW7 WD40 domain targeting" is listed on the "Readers Choice: The best of Oncogenesis 2020" nature.com/collections/ficii…
A postdoctoral position is available immediately in our lab. We study the mechanisms of viral oncogenesis and the life cycle of Merkel cell polyomavirus. #postdoc position #virology #molecular biology
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Identification of the Merkel Cell Polyomavirus Large Tumor Antigen Ubiquitin Conjugation Residue mdpi.com/1175040 via @MDPIOpenAccess
Identification of the Merkel Cell Polyomavirus Large Tumor Antigen Ubiquitin Conjugation Residue

Identification of the Merkel Cell Polyomavirus Large Tumor Antigen Ubiquitin Conjugation Residue

Merkel cell polyomavirus (MCPyV) large tumor (LT) antigen is a DNA binding protein essential for viral gene transcription and genome replication. MCPyV LT interacts with multiple E3 ligases in a...

mdpi.com
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22nd Annual Mini Medical School ce.med.psu.edu/mini-medical-… via @PennStHershey This will be online! Some of our Department members will be participating. Check it out!
Lasting Legacies – Fighting cancer pennstatehealthnews.org/topi… Women in Science!👏👏👏

Lasting Legacies - Fighting cancer

Female faculty at the College of Medicine have been at the forefront of cancer research since the institution’s beginning.

pennstatehealthnews.org
We welcome our new student Alex to our lab! Photos to come...
JCPyV VP1 Mutations in Progressive Multifocal Leukoencephalopathy: Altering Tropism or Mediating Immune Evasion? ##mdpiviruses via @VirusesMDPI
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