Lisa Koshko (@KoshkoLisa) profile picture

Lisa Koshko

@KoshkoLisa

Wayne State Graduate Student, Biological Sciences 🐀🔬🧬🧪

 Detroit, MI
Joined January 2021
  • Tweets19
  • Following40
  • Followers27
Thrilled to share our new study out today in @Diabetes_ADA! 🚨 We explore how #microglia drive metabolic dysfunction triggered by common air #pollutants via the #NFκB pathway. 🧠💥 @CLEARWSU @Wayne_IEHS @WSUBioSci #MetabolicDisorders diabetesjournals.org/diabete…
Microglia Mediate Metabolic Dysfunction From Common Air Pollutants Through NF-κB Signaling

Microglia Mediate Metabolic Dysfunction From Common Air Pollutants Through NF-κB Signaling

The prevalence of type 2 diabetes (T2D) poses a significant health challenge, yet the contribution of air pollutants to T2D epidemics remains under-studied

diabetesjournals.org
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🚨 Our New Publication Alert! 🚨 Our latest study in @GeroScienceAGE reveals how the hypothalamus adapts with age and the sex-specific impacts of Canagliflozin on metabolic control. 📊🧠link.springer.com/article/10… Congrats to @HashanJayarath and our collaborators @SANathanShock
Hypothalamic sex-specific metabolic shift by canagliflozin during aging

Hypothalamic sex-specific metabolic shift by canagliflozin during aging

GeroScience - The hypothalamus undergoes significant changes with aging and plays crucial roles in age-related metabolic alterations. Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are...

link.springer.com
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We are excited for this new @NIEHS @NIH funding with our wonderful collaborator @lempradllab! Hooray for team work and crazy ideas @Wayne_IEHS @WayneStateCLAS – at Ypsilanti, MI
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Great job @scofield_sydney and @KoshkoLisa @CLEARWSU for their presentations at @SOToxicology 2024 – at Salt Lake City, UT
Image from Sadagurski lab (@sadagurski)
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Lisa Koshko retweeted
CLEAR_SRP@WSU (@CLEARWSU) profile picture
CLEAR_SRP@WSU@CLEARWSU5 Mar 2024
We're looking forward to #2024SOT next week! Congratulations to CLEAR trainees Sydney Scofield, Lisa Koshko @KoshkoLisa and Mackenzie Connell @Kenzi615 who will present their posters at the annual conference of the @SOToxicology, and the rest of their teams. @SRP_NIEHS
Image from CLEAR_SRP@WSU (@CLEARWSU)
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#Canagliflozin promotes healthy brain aging #MAC2023 @AgingMidwest @HashanJayarath @WSUBioSci – at Detroit, MI
Image from Sadagurski lab (@sadagurski)
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Our new study by @KoshkoLisa demonstrates persistent adverse effects of #prenatal #VOC exposure on hypothalamic development, predisposing the offspring to long-lasting metabolic disease @CLEARWSU @Wayne_IEHS @WSUBioSci sciencedirect.com/science/ar…
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@Sadagurski's lab is HIRING!! We are looking for a talented #postdoc interested in the hypothalamic regulation of metabolism, and #microglia #astrocytes biology! We have some exciting new #NIH funded #coolprojects and we'd love a new, enthusiastic team member! If interested DM me
Image from Sadagurski lab (@sadagurski)
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Our new bioRxiv preprint by @KoshkoLisa and the team of @lempradllab demonstrates the impact of prenatal exposure to pollution on hypothalamic development and neuroinflammation, predisposing the offspring to metabolic disease @CLEARWSU @NIEHS @WSU_IEHS biorxiv.org/content/10.1101/…
Prenatal benzene exposure alters offspring hypothalamic development predisposing to metabolic...

Prenatal benzene exposure alters offspring hypothalamic development predisposing to metabolic...

The hypothalamus is essential in the regulation of metabolism, notably during critical windows of development. An abnormal hormonal and inflammatory milieu during development can trigger persistent...

biorxiv.org
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Lisa Koshko retweeted
CLEAR_SRP@WSU (@CLEARWSU) profile picture
CLEAR_SRP@WSU@CLEARWSU15 Dec 2022
Great job repping @CLEARWSU at @SRP_NIEHS #SRP35 @KoshkoLisa @sadagurski! This is important research showing how gestational VOC exposure can predispose people to metabolic diseases later on.
Sadagurski lab (@sadagurski) profile pictureSadagurski lab@sadagurski15 Dec 2022
Congrats @KoshkoLisa for excellent job at @SRP_NIEHS @CLEARWSU #SRP35
Image from Sadagurski lab (@sadagurski)
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We are looking for a Research Assistant on neuroinflammation/metabolic disease for an NIH-funded position. Contact me if interested.
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Congratulations to Jana @Bjbiologist of the @GuLabWSU lab, Lisa @KoshkoLisa of the @sadagurski & Mahmoud of the Greenberg lab as recipients of the 2021 Graduate Research Assistant award for their exceptional work in research this past year! Fantastic contributions by all!🥳🎉👏
Image from Wayne State University Biological Sciences (@WSUBioSci)
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Our new study demonstrates that sex-specific effects of @aging drug 17-a-estradiol on neuroinflammation are brain region-specific and are partially controlled by the presence of sex‐specific gonads. Congrats @LucasKDebarba and @HashanJayarath @WSUBioSci academic.oup.com/biomedgeron…

17-α-Estradiol Has Sex-Specific Effects on Neuroinflammation That Are Partly Reversed by Gonadectomy

Abstract. 17-α-Estradiol (17aE2) treatment from 4 months of age extends life span in male mice and can reduce neuroinflammatory responses in the hypothalam

academic.oup.com
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So proud of our team @julianabez_ @LucasKDebarba @heyy_chi and @DarleenSandoval. A new model to dissect the role of GHR-expressing neurons in the aging brain and in metabolism. We show that in the ARC GHR+ neurons regulate glucose metabolism mdpi.com/2073-4409/10/5/1093
Image from Sadagurski lab (@sadagurski)
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Check out our new paper in @ToxSci . Development of diabetes in the offspring following gestational exposure to benzene at the levels relevant to smoking. @KoshkoLisa Ms @WSUBioSci dissertation work, together with @LucasKDebarba
Toxicological Sciences (@ToxSci) profile pictureToxicological Sciences@ToxSci16 Apr 2021
Persistent adult metabolic imbalance following in utero benzene exposure @sadagurski doi.org/10.1093/toxsci/kfab0…
Image from Toxicological Sciences (@ToxSci)
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Lisa Koshko retweeted
chi (@heyy_chi) profile picture
chi@heyy_chi16 Apr 2021
My lab group at @sadagurski lab recently published a paper on the Hypothalamic GHR—SIRT1 Axis in Fasting ##mdpicells via @MDPIOpenAccess Go check it out! 🎉🎉 #undergradresearch #biology mdpi.com/2073-4409/10/4/891
Hypothalamic GHR—SIRT1 Axis in Fasting

Hypothalamic GHR—SIRT1 Axis in Fasting

Many aspects of physiological functions are controlled by the hypothalamus, a brain region that connects the neuroendocrine system to whole-body metabolism. Growth hormone (GH) and the GH receptor...

mdpi.com
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"Antiscience has emerged as a dominant and highly lethal force, and one that threatens global security, as much as do terrorism and nuclear proliferation." | Perspective by @PeterHotez scientificamerican.com/artic…
The Antiscience Movement Is Escalating, Going Global and Killing Thousands

The Antiscience Movement Is Escalating, Going Global and Killing Thousands

Rejection of mainstream science and medicine has become a key feature of the political right in the U.S. and increasingly around the world

scientificamerican.com
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Congrats @KoshkoLisa @LucasKDebarba @julianabez_ @Patric_Fakhoury @WayneGradSchool
Wayne State College of Liberal Arts and Sciences (@WayneStateCLAS) profile pictureWayne State College of Liberal Arts and Sciences@WayneStateCLAS1 Mar 2021
New @WayneState study discovers a connection between pollution and diabetes j.mp/2ZZhoua | @WSUBioSci @WayneGradSchool
Image from Wayne State College of Liberal Arts and Sciences (@WayneStateCLAS)
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Happy to share our new study in @ToxSci demonstrating development of metabolic syndrome in the offspring exposed to pollution during gestation. Congrats to Lisa Koshko for her first paper and @LucasKDebarba @WSUBioSci @Wayne_IEHS @WayneGradSchool doi.org/10.1093/toxsci/kfab0…
In Utero Maternal Benzene Exposure Predisposes to the Metabolic Imbalance in the Offspring

In Utero Maternal Benzene Exposure Predisposes to the Metabolic Imbalance in the Offspring

Abstract. Environmental chemicals play a significant role in the development of metabolic disorders, especially when exposure occurs early in life. We have

academic.oup.com
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