SickKids Peds Nephrology | PhD student | Toronto 🇨🇦 | Aspiring clinician-scientist | Adaptive clinical trials, trial emulation, and health admin data

Joined November 2020
Central venous catheter–related bloodstream infections (CRBSI) are common in children receiving hemodialysis & cause significant morbidity & healthcare costs. Read this Original Article on use of 4% tetrasodium EDTA (KiteLock™) to prevent CRBSI. link.springer.com/article/10…
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Steroid-sparing immunosuppression is used in 50% of children w/nephrotic syndrome, but rates & predictors of prolonged remission after cyclophosphamide & tacrolimus are uncertain. Read this Original Article for more. link.springer.com/article/10…
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I have made the jump over to BlueSky - follow me there at the same handle @KidneyCal bsky.app/profile/kidneycal.b…
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Cal Robinson retweeted
AKI affects a growing number of children and neonates and is associated with high morbidity, mortality, and health care expenditure. In this issue of JASN, Robinson et al. present the findings of a large cohort study on the long-term outcomes of AKI in hospitalized children who did not require acute KRT. In this editorial, @KidneyCathy and @emjsee argue that these findings confirm the poor long-term outcomes of AKI in hospitalized children who do not require acute KRT. bit.ly/JASN0508 @MCRI_for_kids @AU_RMH
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How can simulation be used to improve the design adaptive clinical trials? Read our review article just published in @JASN_News to find out! Big thanks to co-authors @DrRulanParekh @douyang3 @efan75 @BrianCuthberts8 and Anna Heath. journals.lww.com/jasn/citati…
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Long-Term Kidney Outcomes after Pediatric AKI ca. 2024 from @JASN_News #Nephpearls #KidneyWk #BestofJASN #VisualAbstract by @nikkonephro 👉 pubmed.ncbi.nlm.nih.gov/3901…
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Amazing to see a childhood nephrotic syndrome RCT in the #ASNKids24 ⁦@ASNKidney⁩ late breaking trials session! So exciting to see RCTs starting to emerge to improve treatment for these children
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Excellent poster by Cal Robinson et al on a target trial emulation of cyclophosphamide vs CNIs in #nephroticsyndrome ! #ASNKids24 @ASPNeph @ASNKidney
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Come visit our posters today at #ASN2024 #ASNKIDS24 @ASNKidney. PO-720: Comparative Effectiveness of Cyclophosphamide and Calcineurin Inhibitors in Childhood Nephrotic Syndrome PO-386: Health Care Resource Utilization and Costs Associated with Childhood Hypertension
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Cal Robinson retweeted
Using population-based health administrative databases, study investigators found that 1/3 of children with posterior urethral valves develop major adverse kidney events (death, kidney failure, or CKD) by early adulthood, compared with 1% of the general childhood population. bit.ly/JASN0468
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Long-Term Kidney Outcomes in Children with Posterior Urethral Valves #PUV @JASN_News ow.ly/Pqz450T4EnC
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Children with posterior urethral valves are at long-term risk of CKD, kidney failure, and hypertension. One-third develop major adverse kidney events over median 16.6 year follow-up. Kidney health surveillance into adulthood with improved transition planning is needed!
I am thrilled to share our newest paper about long term outcomes in #PUV patients using @ICESOntario data, out today in @JASN_News! journals.lww.com/jasn/abstra… Thanks for the great collaboration @KidneyCal @about__juliane @TimVanMieghem @JoanaRosaP @ChanchlaniRahul @ArmandoJLorenzo
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Cal Robinson retweeted
Meet IMPaCT Fellow @KidneyCal ! Through his research, Cal aspires to advance the evidence-based treatment of pediatric kidney diseases, prevent adverse long-term outcomes, and minimize disease burden. Learn more about Cal’s project here: impactrials.ca/cal-robinson
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Cal Robinson retweeted
Interested in learning how to design and operate clinical trials for pregnant people and kids? 🤰👶🧒 Apply for an IMPaCT training award at impactrials.ca/awardinfo! Applications are open now, so don't miss out – submit by 5 PM CT on October 18, 2024!
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Cal Robinson retweeted
Using population health databases from Ontario, Canada, investigators found that children surviving AKI without acute KRT were at higher long-term risk of CKD, long-term KRT, hypertension, and subsequent AKI compared with hospitalized children without AKI bit.ly/JASN0445
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Youth diagnosed with hypertension are at higher risk of long-term cardiovascular disease, justifying improving blood pressure follow-up and control strategies among hypertensive youth. #PAS2024 ja.ma/4cFRPls
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