Computational biologist. PI at Altos Labs. Formerly from the wonderful DBMI at the Harvard Medical School. Expressed thoughts and opinions are my own.
Altos Labs, San Diego
Joined October 2017
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PeterK retweeted
Excited to share our review @NatureRevCancer! We cover all that we, as a field, learned from our efforts to understand genotype to phenotype interactions in cancer and somatic evolution. We also cover what future measurement technologies can take us in this domain.
PDF link 👇
Lineage tracing with cell state readouts (scRNA-seq, etc.) offers a wealth of information! Navigating such data and extracting biological insights can be tricky, especially with sparse clonal sampling. Sergey's thread and our preprint describe a new analysis tool for such data:
PeterK retweeted
Ever stare at your spatial DE results and wonder if something's off? Segmentation errors might be the culprit. Our new paper shows how pervasive this problem is - and introduces a fix using matrix factorization of local molecular neighborhoods.
nature.com/articles/s41588-0…
