ALT Portrait of Keyur Vora, MD, in a white lab coat, smiling against a gray background, with a quote about the SHIELD-MI clinical trial to the right. Transcribed Text: “SHIELD-MI is the first clinical trial to show that a therapy delivered during the peri-reperfusion period can directly reduce intramyocardial hemorrhage while also limiting infarct size after STEMI. This is important because restoring blood flow with PCI is only the first step; severe microvascular and hemorrhagic injury can continue to damage the myocardium after the artery has been opened.” KEYUR VORA, MD LEAD AUTHOR AND CLINICAL INVESTIGATOR, SHIELD-MI SCHOOL OF MEDICINE MEDICAL IMAGING RESEARCH INSTITUTE Radiology and Imaging Sciences

ALT Close-up of a smiling man with dark hair and glasses in a navy blazer, accompanied by text about cardiac research, including his name and title. Transcribed Text: "Through our cardiac magnetic resonance imaging research, we now understand the influence of infarct size and how microvascular injury leading to intramyocardial hemorrhage can render a 6-fold greater risk of a major adverse cardiovascular event — or MACE." ROHAN DHARMAKUMAR, PHD SENIOR AUTHOR AND PRINCIPAL INVESTIGATOR SCHOOL OF MEDICINE MEDICAL IMAGING RESEARCH INSTITUTE Radiology and Imaging Sciences