
Associate Prof @UCIrvine; Postdoc @UCSF; PhD @mpiNeuro; studying microenvironmental regulation of tissue homeostasis and cancer. @AmericanCancer Scholar
Irvine, CA
Joined January 2018
- Tweets616
- Following217
- Followers603
- Likes1.7K
Kai Kessenbrock retweeted
What a fabulous Day 2 of the #HCA2026GM, sharing ideas and plans for the next phase of the HCA! Please join us tomorrow for Day 3 to help shape the future.
Kai Kessenbrock retweeted
Why is multi-organ #metastasis so hard to treat? Is it organ ("soil")-specific or is there a #systemic program we’ve missed? 🚨 Our new preprint on @biorxiv_cancer reveals a universal, targetable niche conserved across the body. biorxiv.org/content/10.64898… 🧵👇
Kai Kessenbrock retweeted
Replying to @FredHutch_Met_X
@FredHutch_Met_X has launched an open rank faculty search for an innovator who bridges computational and experimental approaches to study cancer metastasis. Please share far and wide!!! @MetastasisRS
nature.com/naturecareers/job….
Kai Kessenbrock retweeted
Excited to share our latest study in @CELL @MDAndersonNews a new single cell DNA&RNA co-assay technology (wellDR-seq) used to study the interactions of DNA copy number and gene expression during breast cancer progression led by @KaileWang @RuiYejerry
cell.com/cell/abstract/S0092…
Kai Kessenbrock retweeted
Check out our new paper identifying the developmental gene PHLDA2 as a robust driver of breast cancer metastasis! Thanks to @PHalasPhD @hannysavage @_DennisMa @KessenbrockLab for all their hard work, and support from @AmericanCancer, @theNCI, & Team Michelle. @UCIMedSchool
PHLDA2 promotes breast cancer metastasis by co-opting a developmental program for placental vascular remodeling biorxiv.org/content/10.1101/… #biorxiv_cancer
Kai Kessenbrock retweeted
Launched today- the Weill Cancer Hub West -supporting transformative cancer research collaborations btw @UCSF & @Stanford. Honored to co-lead, with @longlabstanford, our team who will study the impact of diet on pancreatic cancer initiation, progression and therapy response.
Backed by a $100M gift from Joan and Sandy Weill, UCSF and @StanfordMed @StanfordCancer are launching Weill Cancer Hub West, a $200M initiative in team science to accelerate cancer research and improve care over the next decade.
tiny.ucsf.edu/ppVRqt
Kai Kessenbrock retweeted
Super happy to share our latest in @NatureCancer co-led by @pannunziolab! We review the complex role of the circadian clock in genome integrity, DNA repair, immunity, metabolism, and cancer with a specific focus on early-onset cancer. Check it out!
nature.com/articles/s43018-0…
Kai Kessenbrock retweeted
Congrats @HosungBae @Sunhee_Jung_ Johnny and co-authors for their work! @CellCellPress sciencedirect.com/science/ar…
Kai Kessenbrock retweeted
Postdoc positions are available for deciphering the nuclear RNA degradation code! Email me if interested!
A nuclear RNA degradation code is recognized by PAXT for eukaryotic transcriptome surveillance: Molecular Cell cell.com/molecular-cell/full…
Kai Kessenbrock retweeted
Last night, past Mark Foundation Emerging Leader Award winners gathered with this year’s recipients (@MaraShermanLab @DanWahlMD @LironBarPeled @KessenbrockLab and @Satpathology) to celebrate seven years of this transformational program. #MarkSymposium
Kai Kessenbrock retweeted
I am looking for a postdoc interested in modeling cells and other biological entities/phenomena using AI, physical modeling, and other approaches.
jobs.mdanderson.org/Search/J…
Kai Kessenbrock retweeted
So proud of our lab for attending the Stand up for Science rally in Los Angeles yesterday. You will make a difference ❤️ @NafPascal @isam_adam1 @hannysavage @KessenbrockLab @UCIrvine
Kai Kessenbrock retweeted
Join us 2026 Single-Cell Cancer Biology Conference GRC, @DLawsonlab grc.org/single-cell-cancer-b…
Kai Kessenbrock retweeted
Kai Kessenbrock (@KessenbrockLab), will investigate the hypothesis that inherited BRCA1 mutations cause widespread alterations in breast tissue, including changes to the immune system, which may promote the initiation of breast cancer. @UCIrvine
I’m extremely excited to be part of this amazing program. Can’t wait to get this project off the ground thanks to the generous funding by @TheMarkFdn
📢Announcing The Mark Foundation 2025 Emerging Leader Award winners! 📢
These 5 outstanding early-career scientists will receive a total of $3.75M to pursue projects with the potential to transform cancer research. We can’t wait to see what they achieve!
themarkfoundation.org/2025/0…
Kai Kessenbrock retweeted
Today @NatureSMB, we report that the activation of NF-κB after DNA damage can occur through two distinct mechanisms. While ATM triggers NF-κB activation after DSBs, we found that IRAK1 induces NF-κB in response to DNA damage causing transcriptional stress. nature.com/articles/s41594-0…
Lab holiday party at our house with all the amazing people in @KessenbrockLab and @DLawsonlab. I’m extremely thankful for this awesome group of scientists. Such a pleasure to work and party with all of you! And the crab turned out great too! 🦀👌
Kai Kessenbrock retweeted
Great talk by postdoc @JInsuaRodriguez at the UCI Institute for Immunology annual symposium, describing his work on the role of metastasis associated macrophages in promoting systemic metastasis through immune suppression. @KessenbrockLab @UCIMedSchool
Kai Kessenbrock retweeted
We’re so pleased to see #HumanCellAtlas on the cover of @Nature illustrating the breadth of the HCA initiative, overlaying a subway-style network of biological systems on a detailed cellular map. Congratulations to Claire Agosti from @SayoStudio, and @GraphicAnja
Kai Kessenbrock retweeted
We're starting a new Institute for Engineering + Health at UC Irvine to focus on Rapid Antibody Engineering and Evolution! engineering.uci.edu/news/202…






























