Structural Virology lab, BMB, UTMB & MCB, IU. Viral replication & infection machinery, RNA structure, X-ray crystallography, cryo-electron microscopy
Bloomington, IN
Joined July 2019
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How does enterovirus protease specifically recognize its viral RNA genome?
Hint: It takes two!
Happy to share our publication in @ScienceAdvances
Structure of coxsackievirus cloverleaf RNA and 3C protease dimer establishes its RNA-binding mechanism
shorturl.at/xvrh1
Kay Choi lab retweeted
We are hiring a new editor! If you want to join the Nature Structural & Molecular Biology team and help publish exciting research, please apply. Deadline is June 20th. More information here: springernature.wd3.myworkday…
Post-doc position is available in Choi laboratory at IU. Our research focuses on the structure and function of viral RNAs and replication. Experience in biochemistry or structural biology (X-ray crystallography & cryo-EM) is required. Please apply to kaychoi@iu.edu
Please RT.
Kay Choi lab retweeted
This post is a little late, but the mcmorais lab is happy to announce our recent review on the mechanochemistry of virus dsDNA packaging motors:
pubmed.ncbi.nlm.nih.gov/3950…
Congratulations to my co-authors Josh Pajak, Nikolai Prokhorov, and Paul Jardine
Kay Choi lab retweeted
Check out a new pub from the mcmorais lab on the role of bacteriophage scaffold proteins in the self-assembly and maturation of virus capsids:
science.org/doi/10.1126/scia…
This work was largely driven by my former colleague at UTMB Mike Woodson.
Kay Choi lab retweeted
Want to attend the HCV-Flavi symposium and also to visit the beautiful Singapore? #flavivirus #dengue #zika #arbovirus hcv-flavi2025.org
Kay Choi lab retweeted
IU biology professor Tuli Mukhopadhyay was awarded the 2025 Alice C. Evans Award for Advancement of Women, which recognizes outstanding contributions toward the full participation and advancement of women in microbial sciences. Read more: go.iu.edu/8rwF
Kay Choi lab retweeted
Dengue fever: a record 12.4m cases in 2024 so far (an underestimate) what is driving world’s largest outbreak? Worth putting into context role & effectiveness fogging as mosquito control measure for dengue? The image is dramatic & always used,it’s utility? theguardian.com/global-devel…
Kay Choi lab retweeted
Sustainable investment in basic research is critical. It leads to transformative and sometimes disruptive to the status quo outcomes that improve our lives. doi.org/10.7554/eLife.102368. @ASTMH @utmbnews @ihii_utmb @sbviro @AmerSocVirol @Virology_FAMERP @create_neo @Rossi_viruslab
Kay Choi lab retweeted
Meeting starts soon! Registration ends in 2 days for the Virus Structure and Assembly Conference. See you all in less than a week!😎
Your viral findings could go "viral" at this conference serving researchers since 1990. Join speakers Paula Traktman and Peter Kwong alongside #VSASRC organizers @jurcortines, @GinoCingolani2, @VirusEMLab and more. View the agenda and save your space: hubs.ly/Q02sSjnf0
Congratulations to graduate student @jerrichotipo for winning a poster prize @RNASociety meeting!
Small compounds can distinguish the different RNA bulges in Zika virus stem-loop A for binding.
Don't forget to read the meet the first author section at the end!
Flexible bulge structures of Zika virus SLA RNA bind small molecules differently, offering potential for exploitation in fragment-based drug discovery. #RNA #science #structuralbiology #Zika #drugdiscovery @KayChoi_lab @jerrichotipo bit.ly/3ypyaHh
Kay Choi lab retweeted
Flexible bulge structures of Zika virus SLA RNA bind small molecules differently, offering potential for exploitation in fragment-based drug discovery. #RNA #science #structuralbiology #Zika #drugdiscovery @KayChoi_lab @jerrichotipo bit.ly/3ypyaHh
If you are @RNASociety meeting, check out our posters on RNA structures of HIV Rev response element (RRE)!
@jerrichotipo on Thursday P2-#405
Keerthi Gottipati on Friday P3-#635
#RNA #RNAstructure #HIV
Happy to share our new paper on HIV Rev response element (RRE) @NatureComms. Congratulations @jerrichotipo and Keerthi Gottipati.
Structure of HIV-1 RRE stem-loop II identifies two conformational states of the high-affinity Rev binding site
nature.com/articles/s41467-0…
Kay Choi lab retweeted
Your viral findings could go "viral" at this conference serving researchers since 1990. Join speakers Paula Traktman and Peter Kwong alongside #VSASRC organizers @jurcortines, @GinoCingolani2, @VirusEMLab and more. View the agenda and save your space: hubs.ly/Q02sSjnf0
Kay Choi lab retweeted
Women leave academia at higher rates than men at every career stage, and attrition is especially high among three groups: tenured faculty, women in non-STEM fields, and women employed at less prestigious institutions, a @ScienceAdvances analysis finds. scim.ag/5pH
Kay Choi lab retweeted
We are hiring faculty at the associate and full professor level in Synthetic Biology. Come join us at Indiana University's beautiful Bloomington campus. indiana.peopleadmin.com/post…
I am very sorry to hear this. His love for virus and sense of humor will be greatly missed.
My dear friend @BrettLindenbach passed away on Saturday morning. Hug your loved ones and show up for people in your life. That’s all that matters. legacy.com/us/obituaries/leg…
Congratulations @mcmoraislab!
Check out our new publication in NAR with Carlos Catalano's lab at UC Denver on the bacteriophage lambda dsDNA packaging motor: doi.org/10.1093/nar/gkad1135
