The lab of Andrei Karginov in UIC's College of Medicine. We study #optogenetic and #chemogenetic regulation of kinases and phosphatases. Student-run account.

Joined May 2022
Huge congratulations to Dr. Nic Leschinsky for defending his thesis last week! 🥳🎉
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A few weeks ago we took a lovely trip to Brookfield Zoo with the lab to see some fish, seals, and hippos.
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We're excited to be participating in the FASEB Protein Phosphatases Conference next week! If you're interested in talking all things Shp2, Barbara will be at poster 8b on Tuesday after her Flash Talk. #PPCSRC22
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We had our Summer picnic this weekend and got to enjoy good company, good food, and great weather! ☀️
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Image shows combining parallel Shp2-mediated pathways to reconstruct cell morphodynamics. Fauser et al. @KarginovLab @UICPharmacology engineer a chemogenetic allosteric switch that allows for the regulation of the activity of protein tyrosine phosphatases bit.ly/3nX5hK6
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Big congratulations to Dr. Jordan Fauser for her successful defense today! 🎉
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Thank you to all who made our recent publication possible! #allostery #allosteric #regulation #chemogenetics #AcademicChatter #publication #AcademicTwitter
Jordan Fauser et al @KarginovLab @UICPharmacology engineer a chemogenetic allosteric switch that allows for the regulation of the activity of protein tyrosine phosphatases, as well as for their activation within specific protein complexes bit.ly/3nX5hK6 #Biochemistry
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We are excited to present our latest work! Using an engineered allosteric switch, we regulate Shp2 phosphatase activity and dissect downstream dynamic signaling events. We then expanded this approach to regulate PTP1B and PTPPest rupress.org/jcb/article/221/…
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We were so excited to share our work on #optogenetic regulation of kinases at @FASEBorg #PKPSRC22. Thank you to the wonderful event organizers!
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InSiDE 2022 starts in a week! Join us next Thursday June 9 at a special time (23:00 GMT) for what is sure to be a great seminar by Shinya Kuroda!
InSiDE kicks off with our regular seminar series in June! Check out the link in bio for speaker lineup, and register for our poster session on June 16!
We're excited to share our recently published review on allosteric regulation in @JMolBiol! authors.elsevier.com/a/1f49X… #review #allostery #allosteric #regulation #AcademicTwitter #AcademicChatter #Publication
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