(ii) We’ve developed a model explaining how mtDNA deletions occur [bmcbiol.biomedcentral.com/ar…]. Disrupting certain repeats can lead to healthier, longer lives—exactly what we observe in long-lived Japanese individuals [biorxiv.org/content/10.1101/…]! 🌍
(iii) Now we need to push companies in mitochondrial medicine to use mtDNA with disrupted repeats for new therapies like mitochondrial replacement and transfer. Let’s move forward! #Mitochondria #Longevity #aging
Konstantin Popadin retweeted
New #openaccess #research from @KPopadin & colleagues shows that formation of age-associated deletions in #human #mtDNA is influenced not only by #DNA similarity between breakpoint regions but also by topological proximity bit.ly/3I2uBZB #aging #replication #mitochondria
Konstantin Popadin retweeted
Our latest research on the combined impact of genetics and infection on the risk of cardiovascular disease actu.epfl.ch/news/oral-bacte… @epflSV @CHUVLausanne
One important step to uncover a source of mitochondrial mutations: the older the somatic cell/oocyte/organism, the more A>G mutations on a single-stranded heavy chain. We propose that A>G is a hallmark of age-associated oxidative damage. (1/3)
read this: pubmed.ncbi.nlm.nih.gov/3613…
(2/3)
"Мама, нас обманули: на небе лишь только звёзды"
youtube.com/watch?v=jKB5CMVG…
Не ходите на войну в Украину. Нас обманули. Живите и дайте жить другим.
Konstantin Popadin retweeted
Несколько месяцев назад Путин обещал, что никакой мобилизации не будет. Надеюсь, это видео посмотрят в каждой семье, из которой он сейчас хочет забрать кого-то на смерть
Konstantin Popadin retweeted
The data on cannabis use in young people (age 12-18) leading to schizophrenia and psychosis later in life even after cessation of cannabis use, are striking, concerning & lend balance to the idea that cannabis is harmless or better b/c it is “safer than alcohol”.
Konstantin Popadin retweeted
An article about session on war in Ukraine @APSphysics annual meeting. I spoke at different one on human rights and scientists - will share separately slides & messages @OksanaPyzikUCL @femtoQ @sguriev @AlexKrasnok @Joseph_DeSimone physics.aps.org/articles/v15…
Konstantin Popadin retweeted
Please share: Statement from Russian-speaking academic diaspora in support of scholars affected by the Russian aggression in Ukraine. sites.google.com/view/protec… @sguriev @femtoQ @AlexKrasnok @aaas @theNASEM @americanacad @acad_euro @UNC_CSEEES @DCRES_Harvard
Konstantin Popadin retweeted
Запад разделился сейчас на две части. Первые - это те, кто не хотят, чтобы началась Третья мировая война, и вторые, которые понимают, что Третья мировая война уже началась.
Konstantin Popadin retweeted
Propaganda is a very strong force. Nevertheless, people in Moscow are divided. It has been a privilege being a part of a considerable crowd today, even though many participants, myself included, were arrested minutes later.












