@JonathanHGeorge

Associate Professor of Organic Chemistry at the University of Adelaide

Joined January 2015
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📢 JOB ALERT: We will soon be advertising a PDRA (postdoc) position in #TotalSynthesis @EdinburghChem to start in early (ideally February) 2024. The advert will go live soon but please contact me by email if you any questions. #chemjobs
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Lauren Murray@laurenammurray26 Aug 2023
Incredibly excited to announce that my @arc_gov_au #DECRA has been funded! Exciting science to come with the Cryle and @Challis_Group @MonashBDI! I am so grateful for the continued support of all my amazing mentors along the way! #DE24
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Latest total synthesis is on ChemRxiv - a truly comprehensive dearomatization strategy! Congratulations to @AndreaszBonsen and thanks to @chriszombiechem for the X-ray structures Bioinspired Total Synthesis of Hyperireflexolides A and B | ChemRxiv - go.shr.lc/3DbWbkc
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Nick Green@NickGreen_chem6 May 2023
Thrilled to see our paper in @J_A_C_S today on amino acid derivative #prebiotic #chemistry that could have occurred in formamide on a primordial Earth. Thx to coauthors David, John (@MRC_LMB🇬🇧) and Sasha (undergrad in my lab at @otago 🇳🇿🥝)! #originoflife pubs.acs.org/doi/10.1021/jac…

Prebiotic Synthesis of N-Formylaminonitriles and Derivatives in Formamide

Abstract. Amino acids and their derivatives were probably instrumental in the transition of prebiotic chemistry to early biology. Accordingly, amino acid f

pubs.acs.org
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Dave Leigh@ProfDaveLeigh25 Apr 2023
Advances in synthesis & analysis enable old claims to be reexamined with new tools🔎🕵️ In @J_A_C_S, @AndreiBaluna @AlbanoGalan @JustinTJSpence et al retrace footprints in the sands of history in search of the 1st catenane: was it molecule or merely myth? pubs.acs.org/doi/10.1021/jac…
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Phillip Grant@Phillip_S_Grant2 Mar 2023
Check out our biomimetic approach to cyclopropanes! 🌿 Nature is one hell of a synthetic chemist – it pays to learn from the best. Thanks to all my awesome colleagues for helping bring this together! @MaulideLab
J. Am. Chem. Soc.@J_A_C_S1 Mar 2023
Biomimetic Cationic Cyclopropanation Enables an Efficient Chemoenzymatic Synthesis of 6,8-Cycloeudesmanes @MaulideLab @univienna @TotalSyntheses #Biomimetic #Cationic #Cyclopropanation #Chemoebzymatic #Synthesis #Eudesmanes pubs.acs.org/doi/10.1021/jac…

Biomimetic Cationic Cyclopropanation Enables an Efficient Chemoenzymatic Synthesis of 6,8-Cycloeu...

Abstract. Cationic cyclopropanation involves the γ-elimination at carbocations to form a new σ-C–C bond through proton loss. While exceedingly rare in bulk

pubs.acs.org
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Donohoe Group@DonohoeGroup23 Jan 2023
Our first paper of 2023 is out now in @JOC_OL, a metal & activating group free method for the C4 alkylation of isoquinolines Congrats to Aaron @brokentesttubes, Tim & Marvin! This work was a collab with @GSK & special thanks go to Darren @DPSynthChemist bitly.ws/zgKP
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Deeply honoured to be named as a finalist in Chemistry for the UK @BlavatnikAwards! This is a great recognition of all the hard-work & creativity of my past & present co-workers @EdinburghChem. Hearty congratulations to my fellow finalist @JeskoKoehnke & laureate Susan Perkin!
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Delighted to see this work published in @ChemicalScience Check it out if you’re interested in total synthesis and cascade reactions! pubs.rsc.org/en/content/arti…

A bioinspired, one-step total synthesis of peshawaraquinone†

A concise synthesis of a stereochemically complex meroterpenoid, peshawaraquinone, via the unsymmetrical dimerization of its achiral precursor, dehydro-α-l

pubs.rsc.org
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Nick Green@NickGreen_chem20 Dec 2022
Don't forget to get in contact if you are interested in a Marsden PhD scholarship in origins of life organic chemistry. First round of interested applicants will hear back in January
Nick Green@NickGreen_chem5 Dec 2022
🚨PhD and Research Assistant Opportunities🚨 My group in organic and biological chemistry at University of @Otago has a FULLY FUNDED PhD SCHOLARSHIP (35k NZD p.a.+ tuition fees), on origins of life chemistry. We are also hiring a research associate. Details below. Please RT.
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Congratulations to Sarah @Teamfrench_ for her new total synthesis! With thanks to @chriszombiechem for X-Ray structures and @dmhuanglab for calculations Total Synthesis of Atrachinenins A and B pubs.acs.org/doi/10.1021/jac…

Total Synthesis of Atrachinenins A and B

Abstract. Inspired by a new biosynthetic hypothesis, we report a biomimetic total synthesis of atrachinenins A and B that explains their racemic nature. Th

pubs.acs.org
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Nick Green@NickGreen_chem5 Dec 2022
🚨PhD and Research Assistant Opportunities🚨 My group in organic and biological chemistry at University of @Otago has a FULLY FUNDED PhD SCHOLARSHIP (35k NZD p.a.+ tuition fees), on origins of life chemistry. We are also hiring a research associate. Details below. Please RT.
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Bradley Moore@BradMoore_SIO20 Aug 2022
Vanadium-dependent haloperoxidase enzymes have always fascinated us @moorelabsio for their biosynthetic dexterity. We're delighted to finally share some beautiful structures in @BiochemistryACS pubs.acs.org/doi/pdf/10.1021…
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Please check out our latest one-step total synthesis of a complex natural product. Congratulations to lead author Tomas and thanks to @dmhuang @chriszombiechem @biomimetic_chem for their valuable contributions! chemrxiv.org/engage/chemrxiv…
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Angewandte Chemie@angew_chem15 Jul 2022
Intramolecular Tricarbonyl-Ene Reactions and alpha-Hydroxy-beta-Diketone Rearrangements Inspired by the Biosynthesis of Polycyclic Polyprenylated Acylphloroglucinols (George) #openaccess @JonathanHGeorge onlinelibrary.wiley.com/doi/…
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Congratulations to Andreas for this paper outlining some chemical speculation on the biosynthesis of rearranged PPAP natural products onlinelibrary.wiley.com/doi/…

Intramolecular Tricarbonyl‐Ene Reactions and α‐Hydroxy‐β‐Diketone Rearrangements Inspired by the...

Chemical speculation on the biosynthesis of some complex meroterpenoids led to the discovery of intricate cascades that feature spontaneous intramolecular carbonyl-ene reactions, α-hydroxy-β-diketo...

onlinelibrary.wiley.com
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ChemBark@ChemBark11 Apr 2022
A short thread on disability in chemistry and some food for thought. Again, I hate to be the one writing this. I'd much rather someone else did it so I could just retweet, but here we are... (1/12)
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Thomas Fallon@Thomas__Fallon16 Mar 2022
Two Steps to Bicyclo[4.2.0]octadienes from Cyclooctatetraene: Total Synthesis of Kingianic Acid A | Organic Letters. Congrats to Harshal Patel! pubs.acs.org/doi/10.1021/acs…
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Angewandte Chemie@angew_chem15 Mar 2022
Bioinspired #TotalSynthesis of Erectones A and B, and the Revised Structure of Hyperelodione D (George) @AdelaideChem @JonathanHGeorge #openaccess onlinelibrary.wiley.com/doi/…
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