Twitter for the Jon Brown Lab, located in the division of cardiovascular medicine at Vanderbilt University Medical Center. @VUMChealth š§¬ āļø
Nashville, TN
Joined April 2020
- Tweets48
- Following242
- Followers131
- Likes140
Jon Brown Lab retweeted
Happy Thanksgiving š¦šš½ from this rockstar ā¦@VUMCMedicineResā© ā¦@VUMC_Medicineā© team! Grateful to get to work alongside these amazing doctors. #WomenInMedicine Thx to all #healthcareworkers serving today!
Jon Brown Lab retweeted
Congrats to Ronan Bracken graduate student in @JonBrownLab. Advancing to PhD candidacy in @VandyBiochem. #donewithquals!!! šš§¬š§¬š§¬
Jon Brown Lab retweeted
Join us in welcoming our new #TechnicalEditor @CircRes Dr. Amanda Doran MD PhD from the Division of Cardiology @VUMC_heart. Her research focuses on the role of innate immunity and #inflammation resolution in #atherosclerosis. Congratulations! @AmandaDoranLab
Jon Brown Lab retweeted
Big congrats to outstanding colleague & "Cardio-Immunologist" extraordinaire! & fellow PRB3 "neighbor" (well...until a few months ago)! @VUMChealth @VUMC_heart @AmandaDoranLab @JonathanBrownMD @JonBrownLab @JaneFreedmanMD @CircRes @AHA_Research @annetkiraboc1 @nhpetunia
Join us in welcoming our new #TechnicalEditor @CircRes Dr. Amanda Doran MD PhD from the Division of Cardiology @VUMC_heart. Her research focuses on the role of innate immunity and #inflammation resolution in #atherosclerosis. Congratulations! @AmandaDoranLab
Jon Brown Lab retweeted
Our recent publication was reviewed in NEJM today! @davidrliu, @NIHDirector, @JonBrownLabVUMC, @Progeria, @mrrerdos The figure is absolutely killer!
Will definitely be sending this to my mom.
nejm.org/doi/full/10.1056/NEā¦
Jon Brown Lab retweeted
Excited to have Dr. Mac Linton present at @VUMChealth CV Research Series. Terrific colleague, scientist & even better hogfish cook & host! @JaneFreedmanMD @KathrynMooreLab @merrymanlab @alan_daugherty @JoshuaBeckmanMD @VAgrawalMDPhD
Jon Brown Lab retweeted
Read this study from Paul Cohen @RockefellerUniv about Brown Fat in humans and risk of cardiometabolic disease. Nice to see independent work from former @BrighamFellows. nature.com/articles/s41591-0ā¦
Jon Brown Lab retweeted
The findings of a study in Nature demonstrate the potential of in vivo base editing as a possible treatment for HutchinsonāGilford progeria syndrome and other genetic diseases by directly correcting their root cause. go.nature.com/38ktlQ1
Jon Brown Lab retweeted
News & Views: No cure exists for the lethal premature-ageing condition HutchinsonāGilford progeria. A gene-editing tool offers a way to treat the condition in mice, according to a Nature paper. Could this approach lead to an effective therapy? go.nature.com/3oom0EJ
Jon Brown Lab retweeted
In vivo base editing shows promise in treating the genetic accelerated-aging disorder HutchinsonāGilford progeria syndrome in mice - find out more in our latest highlight of research by @jonbrownlabVUMC
@davidrliu @LiuGroup et al. go.nature.com/3igjwpJ
Jon Brown Lab retweeted
Research from the @JonBrownLabVUMC and collaborators have rescued mice afflicted with progeriaāaccelerated agingāwhich could lead to a cure for Hutchinson-Gilford progeria syndrome in humans.
news.vumc.org/2021/01/06/genā¦
Jon Brown Lab retweeted
Congratulations to @SarnoffCardio & @BrighamFellows alumnus/current @VUMChealth cardiologist Dr. John Brown. Really nice story & demonstrating power of teamwork. Can studying progeria provide insights into CV aging? @JonBrownLabVUMC @saptarsi_haldar @tmmichelangelo @Progeria
So proud of this work demonstrating DNA base editing treatment for #progeria in human cells & mouse model. Amazing collaborative team @davidrliu @NIHDirector @LukeKoblan & Mike Erdos at NIH and my @VUMCResearch team @lindsaymdavison & Sean Doherty
rdcu.be/cc90j
Jon Brown Lab retweeted
Great science marches on.
A rare incurable diseaseāprogeriaātackled by #CRISPR genome editing with striking results in mouse model
nature.com/articles/s41586-0ā¦
@nature @davidrliu @NIHDirector @LukeKoblan @JonBrownLabVUMC
David's ā
š§µš
xitter.cf/davidrliu/status/13468ā¦
Today we report the use of base editing in patient-derived cells and in mice to correct the most common cause of progeria, the devastating rapid aging disease. Progeria is typically caused by a dominant negative Cā¢G-to-Tā¢A point mutation in LMNA. 1/11 drive.google.com/file/d/1oH4ā¦
Jon Brown Lab retweeted
So proud of this work demonstrating DNA base editing treatment for #progeria in human cells & mouse model. Amazing collaborative team @davidrliu @NIHDirector @LukeKoblan & Mike Erdos at NIH and my @VUMCResearch team @lindsaymdavison & Sean Doherty
rdcu.be/cc90j
Jon Brown Lab retweeted
Here is a really great article about our progeria work that mentions the early days where we only had DNA editing data from only a single LMNA c.1824 C>T mouseā @davidrliu, @JonBrownLabVUMC, and @NIHDirector may remember fondly! Check it out here: statnews.com/2021/01/06/crisā¦
Jon Brown Lab retweeted
Today we report the use of base editing in patient-derived cells and in mice to correct the most common cause of progeria, the devastating rapid aging disease. Progeria is typically caused by a dominant negative Cā¢G-to-Tā¢A point mutation in LMNA. 1/11 drive.google.com/file/d/1oH4ā¦
Jon Brown Lab retweeted
I am incredibly thankful to have worked with such an amazing team led by @davidrliu, @JonBrownLabVUMC, and @NIHDirector with amazing contributions from Leslie Gordon at the PRF (@progeria) and all of our co-authors (especially my co-first author Mike Erdos)
Light at the end of the tunnel!
So thankful that #frontlineworkers and #HealthcareHeros are able to get the vaccine.
