@BMC_UW #epigenetics lab | Focused on mechanisms and biological function of reversible protein modifications #chromatindynamics #metabolism #microbes 🧪🧫🧬🔬🦠
Madison, WI
Joined April 2020
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Excited for our newest publication about how the intrinsic kinetics of H3K9 HMTs maintain H3K9me1 under low SAM levels! Great work, @SpencerHaws, @lilymiller88, and Slava! Check it out!
jbc.org/article/S0021-9258(2…
Great work, @LauraSteenberge and @Pagliarini_Lab! 🧫🧪👩🏼🔬
CoQ10 is large and very hydrophobic, which limits its bioavailability. Our new study, led by @LauraSteenberge, shows that CoQ4 is a sufficient substitute for multiple CoQ functions in cells and can be targeted to mitochondria. biorxiv.org/content/10.1101/…
#bioRxiv
#mitochondria
#CoQ
Check out our newest publication in @jbiolchem in press this week titled "Intrinsic catalytic properties of histone H3 lysine-9 methyltransferases preserve monomethylation levels under low S-methionine"!
Have you checked out our newest articles in press this week? Here you go! jbc.org/inpress. You can also get them sent straight to your inbox. Register for email alerts here: jbc.org/action/registration#…
Denu Lab retweeted
Fluorogenic Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide Activated SIRT7 biorxiv.org/cgi/content/shor… #bioRxiv
So jazzed about this preprint! There is so much to learn about SIRT7 with this new fluorogenic assay! ✨
New preprint on @bioRxiv
In collaboration with @JosephRogers100, @JohnDenuLab, and #PernilleHarris lab, we developed an in vitro assay for evaluation of SIRT7 modulators, performed #SAXS studies, and discovered cyclopeptide inhibitors, using #RaPID
biorxiv.org/content/10.1101/…
ALT Olsen Lab, Biopharmaceuticals, University of Copenhagen, SIRT7 assay and modulators
Congratulations, Zhangli! 🎉 Can't wait to see what your lab accomplishes! 🧪🧫🧬
A personal update while working on #RNA23 badge... Excited to announce that Su Lab will open its door @UABGenetics in July! We are recruiting at all levels for anyone who is interested in RNA modifications, gene regulation, NGS analysis and cancer biology. (1/4)
Stop by Lily's seminar to hear about her thesis work investigating the catalytic mechanisms of epigenetic enzymes! 🧬🧫🧪📈🧵
IPiB seminar this week will be given by Lily Miller (@lilymiller88) from the Denu Lab (@JohnDenuLab). More info: ipib.wisc.edu/uw-event/ipib-…
ALT Seminar poster.
Great job presenting your studies about how diet can affect host epigenetics and Alzheimer's! 🍽️🦠🧫🧬
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Always jazzed to talk about how metabolism and epigenetics are intertwined. Thanks, EpiCypher!
Yesterday we were pleased to host @JohnDenulab for a lively discussion of his lab's latest research on how the #epigenome responds to metabolic stress. Thank you for visiting and being a part of our continuing education series at EpiCypher!
Congrats, @briansmithlab!
We're excited for our PBRM1 bromodomain inhibitor work to be featured in @PracticalFrag! A nice example of our @mcwchembio fragment screening pipeline. Thanks to @EmilyDykhuizen for cell work. @MedicalCollege @MCW_Research
So saddened to hear about the passing of C. David Allis. Wonderful work done in the chromatin field and more importantly, such a wonderful colleague. You will be missed.
Such a great resource!
Just updated and expanded: our massive database of postdoctoral fellowships. These are all fellowships NOT attached to any specific university.
We include description, $ amount, deadline, field, and eligibility criteria.
Download it here: research.jhu.edu/rdt/funding…
Happy International Day of People with Disabilities! And thanks to the @Hull_Lab for always keeping us up-to-date with these important days!
🧬🧪🍻
If you are in a @uwgenetics or @uwmadisonipib lab come join us for a social lunch tomorrow in BSB Atrium. We'll have food, dope people doing dope science, and good vibes!
Jazzed to co-host @PospisilikJ for today's inaugural Jim and Katie Krause Metabolism Seminar! Come join us for an awesome seminar at 3pm!
