PDRA UoS bioremediation | Previously @LSTMnews | PhD RNAi UoSheffield |Biochem/tech βœŒοΈβš—οΈ | Former EiC @MotionPod | @JohnSefParkGrn πŸ’š| He/him πŸ³οΈβ€πŸŒˆ |

Sheffield, England
Joined October 2019
I now have a separate account for all things @LiverpoolGreens! Won't be doing a lot with it until the new year but follows are much appreciated in the meantime πŸ˜ŠπŸ’š xitter.cf/JohnSefParkGrn?t=S_nyQ… – at Liverpool, England
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
Starting to write up the first mechanistic paper from my lab about endosomal PI(3)P: Retromer tubules (Vps35) budding from PI(3)P positive sorting endosomes with Actin at the neck. When PI(3)P homeostasis is perturbed this organisation breaks down and cells cant recycle cargo
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
My favourite image of the week, algae in microdroplets…πŸ§ͺ
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
Last night John Howard spoke at Pint of Science 🍺πŸ§ͺ: β€œThe Circle of (Micro)life - how microbe cooperation could help pollution remediation & agriculture." More: wix.to/C0KX5vf #PintOfScience #Microbes #SciComm
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
Beers to β€œend” the week…except having to work Saturday 😭
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
Engineering synthetic co-cultures to be "needy" leads to unexpected consequences. We barely scratch the surface here, but get some interesting insights #biotech πŸ§ͺ sciencedirect.com/science/ar…
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
More outsourcing of critical thinking to chat bots that do not give any creative or actually inspiring feedback. True innovation will come to an end as people get more and more dependent on LLM to tell them what they want to hear.
BIG ANNOUNCEMENTπŸ“£: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!πŸ™€πŸ₯³ It started from my frustration with the depressing effect that the current publishing system has on the well-being of myself, my team, and pretty much every scientist I know (maybe you’ve noticed from my stupid jokes… :) I was exhausted of dealing with the huge delays, reviewers that can be abusive, and how arbitrary it all is. Unfortunately, the most important factors are often WHO your reviewers are and who YOU are... It’s clear we need alternatives or at least ways to improve the situation. So, together with a really special and talented team we worked to develop this idea into β€œqed” a platform where you can get CONSTRUCTIVE feedback on your own work or CRITICALLY assess other people’s papers. It can be a real difference maker if many of you join us (thousands have tried it already, but today we release a NEW and much stronger version ;) Let’s harness qed to put the power back in the scientists’ hands, to do, to read & to publish science on our own terms. I’m dying for you to TRY IT, and it’s very simple - just drop a paper (the link to the website is in the repliesπŸ‘‡) - it’s completely secure, private, and free, and you get results fast. Please show your support, SHARE, tell your friends, and let’s be the revolution 🫡!
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
70 years ago, a woman discovered the structure of DNA. But 2 Cambridge men stole her work and won the Nobel Prize. She was erased from history and died of cancer. Here’s how the biggest theft in science buried Rosalind Franklin’s name in history… 🧡u
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
Pace of parks' protection plan criticised: bbc.co.uk/news/articles/c0lz…
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
Tomorrow is by-election day in Hunts Cross and Much Woolton. Vote for Mike Bates of the Green Party for a greener, healthier Liverpool
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
5 years after herbicide use ended, Hoylake foreshore is thriving: 240+ plant species βœ… 42k tonnes of sand captured annually, saving Β£45k βœ… Home to 2% of UK’s embryonic dunes βœ… Peat soils forming βœ… 30ha of rare habitat = biodiversity, protection, carbon capture 🌱❀️
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
A day of trying to salt routes through ice on pavements at junctions around Lark Lane (we'll see how well that works or not πŸ˜…), unblocking drainage grates in the park, & checking on a fence that was mended a little while back. – at Liverpool, England
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
Happy New Year! Got a free afternoon? Today's your last chance to visit the Maritime & Slavery museums for several years! Huge programme of works ahead, including moving the Slavery museum to a new bigger home just round the corner liverpoolecho.co.uk/news/liv…
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
.@hannes_maib et al present a toolkit for visualization of phosphoinositides in fixed cells & tissue, enabling multiplex & super-resolution characterization of these signaling #lipid hubs.la/Q02_5lKD0 Part of the Year in Cell Biology: hubs.la/Q02_5l790 #CellBio2024
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
Incredibly honoured to have my first paper as PI highlighted in this collection! The idea was do a quick tool paper as start into independence and it turned out to be much more useful than I thought. Read about how to use recombinant biosensors to stain for lipids in fixed cells!
Our annual collection highlights twelve of the most outstanding papers that showcase the exceptional range and quality of research published by JCB. We are delighted to serve as an independent venue for the awe-inspiring world of cell biology! hubs.la/Q02_fVs30 #CellBio2024
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I've made Parks & the tree maintenance people within the council aware of the fallen tree across the path in Sefton Park so it can be dealt with. There's obviously a list of stuff after the storms & more dangerous things elsewhere in the city will get done first @ILoveSeftonPark
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
OVER THE MOON! 😍 Golden bog-moss (Sphagnum pulchrum), a nationally v rare beastie, was presumed extinct on Britain’s 3rd largest raised bog… That is, until today, where I stumbled upon this teeny area where it’s clinging on for dear life! Isn’t it a beaut? 😍🌱
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
PI3K dependent rearrangement of the actin cytoskeleton following the addition of Class I PAK kinase-inhibitor. Please read about it in our pre-print!
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
"We placed tracking devices in 40 bundles of soft plastic packaging & dropped them at front-of-store collection points at @sainsburys and @Tesco across England.... 70% of the tracked bundles that reached a final destination were burnt, not recycled" πŸ€¦β€β™‚οΈπŸ˜€ you.38degrees.org.uk/petitio…
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Dr John D Howard πŸ‘¨β€πŸ”¬πŸŽΉπŸ³οΈβ€πŸŒˆπŸ³οΈβ€βš§οΈπŸ‡ΊπŸ‡¦πŸ‡΅πŸ‡ΈπŸ’š retweeted
The 2024 #NobelPrize in Physiology or Medicine focuses on the discovery of a vital regulatory mechanism used in cells to control gene activity. Genetic information flows from DNA to messenger RNA (mRNA), via a process called transcription, and then on to the cellular machinery for protein production. There, mRNAs are translated so that proteins are made according to the genetic instructions stored in DNA. Since the mid-20th century, several of the most fundamental scientific discoveries have explained how these processes work. In 1993, this year's Nobel Prize laureates published unexpected findings describing a new level of gene regulation, which turned out to be highly significant and conserved throughout evolution. They discovered microRNA, a new class of tiny RNA molecules that play a crucial role in gene regulation. Read more: bit.ly/4dlPE6f
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