A kidney-obsessed, learning liver doctor. Lover of the hustle - probably got it from my mama. When I tweet - they’ll be my own.
New York, NY
Joined April 2013
- Tweets480
- Following1.2K
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Giuseppe Cullaro retweeted
Dario is right
We Must Pace the Frontier: I’ve written a new essay on why the AI industry should slow down, with a three-part plan for doing so.
Anthropic is unilaterally committing to the first of these steps. We’ll provide third-party evaluators with permanent, employee-level access to our systems, so that they can verify adherence to our safety measures, report on incidents, and assess models’ alignment during training.
You can read the full post here: darioamodei.com/post/we-must…
Giuseppe Cullaro retweeted
Real-world use of terlipressin for HRS-AKI in the US here.
➡️16-center (n=243 patients)
🔹 Overall Response: 55.1%
🔹 HRS Reversal: 30.9%
🔹 90-day mortality: 40.5%
➡️50% Extended Criteria (presence of ≥1 FDA warning) mostly 2/2 ACLF grade 3.
pubmed.ncbi.nlm.nih.gov/4210…
Giuseppe Cullaro retweeted
To all new Ferrari fans ‼️
A quick reminder that these little moments of hope during testing could very well be the best moments of our year.
We drink the Holy Hopium. We rejoice in our capable drivers.
For next year is always our year.
Love,
A Ferrari fan for 35+ years
Giuseppe Cullaro retweeted
When used wisely albumin can help patients with cirrhosis says the best meta-analysis on this in @HepCommJournal
journals.lww.com/hepcomm/ful…
But these trials are small and misuse - SO COMMON - outside of trials is harmful. How to thread the needle?
Giuseppe Cullaro retweeted
@JoeCullaro , our ⭐️ hepatologist (nephrologist in another life?), presenting his research on cystatin c's role in mortality prediction in patients with cirrhosis #livertwitter #GItwitter #TLM25
Giuseppe Cullaro retweeted
First Domino Split-Liver Transplant in Adults in the United States healthmatters.nyp.org/one-li…
Giuseppe Cullaro retweeted
What an amazing day in Teaneck, NJ at the @ColumbiaSurgery @ColumbiaMed Liver Disease Summit!
Giuseppe Cullaro retweeted
How common is ambulatory AKI (AKI occurring in an outpatient setting) in cirrhosis?
✅It’s common➡️1 in 8
✅Underrecognized➡️42%
✅Key precipitants➡️hypovolemia 2/2 diuretics & GI losses, & nephrotoxin medication exposure
✅Deadly➡️1 in 8 ☠️at 90d
🔥🔥cghjournal.org/article/S1542…
Giuseppe Cullaro retweeted
Original Article
The relationship between mean arterial pressure and terlipressin in hepatorenal syndrome-acute kidney injury reversal: a post hoc analysis
Cullaro et al.
#LiverX
tinyurl.com/2pe5uasn
thelancet.com/journals/langa… - congrats @KavishPatidar11 - super impactful.
Giuseppe Cullaro retweeted
What is the relationship btwn terlipressin & MAP
From the genius of @JoeCullaro
journals.lww.com/hep/abstrac…
🔥post-hoc analysis, patient-level data from REVERSE and CONFIRM.
🔥In a time dependent model, 5 mmHg ⬆️ in MAP was associated with 1.17x the hazard of HRS-AKI reversal.
Giuseppe Cullaro retweeted
Learn to conduct clinical research with past AASLD presidents, lectures and sit down in round table discussions with Drs. Anna Lok, Vijay Shah, Jorge Marrero, and Gaudalupe Garcia-Tsao Monday at 2pm, 2 sessions! #TLM2024 @AASLDtweets @JoeCullaro @BlaneyMD @Mironova_MD @DrLoomba
Giuseppe Cullaro retweeted
Keeping MEAN ARTERIAL PRESSURE high is a major goal in critically ill liver patients with AKI and increases survival.
This key issue in patient management is discussed by Dr. Enric Reverte from @LiverIcu at the #IMTLD2024
Giuseppe Cullaro retweeted
Welcome @JoeCullaro and @yael_nobel! The two newest members of our CLDT Team.
Giuseppe Cullaro retweeted
There's a new vitamin C you have to check to assess waitlist mortality. Cystatin C (💥word play). Check out @JoeCullaro new article!
journals.lww.com/lt/abstract…
Giuseppe Cullaro retweeted
Long-term continuous terlipressin infusion improves cardiac reserve in patients with decompensated cirrhosis - Clinical Gastroenterology and Hepatology cghjournal.org/article/S1542…
Giuseppe Cullaro retweeted
I know what quantile regression is, but could you explain it for a friend of mine who may not understand as well as me? Sure, says Drs. @LieberLuvsLiver and Jiang journals.lww.com/lt/abstract…
Giuseppe Cullaro retweeted
Cystatin will C serum creatinine later! Is it a better at predicting mortality? Let's see what @JoeCullaro had to say 👀👀👀
journals.lww.com/lt/abstract…