TB Research Scientist - Principal Investigator @VIDOInterVac @Usask Also on https://xitter.cf/t.co/mKBPYWh2MQ - all views, opinions and comments are my own

Canada
Joined March 2020
Jeffrey Chen retweeted
Our former Prime Minister, Jean Chrétien, turned 91 today. This is HIS "post": "A gift to Canada from Jean Chrétien on his 91st birthday. LOVE this guy!!! "Jean Chretien is 91 today and he gave himself a birthday present. He told Donald J. Trump to piss off in the The Globe and Mail. Here's his column: * * * Today is my 91st birthday. It’s an opportunity to celebrate with family and friends. To look back on the life I’ve had the privilege to lead. And to reflect on how much this country we all love so much has grown and changed over the course of the nine decades I’ve been on this Earth. This year, I’ve also decided to give myself a birthday present. I’m going to do something in this article that I don’t do very often anymore, and sound off on a big issue affecting the state of the nation and profoundly bothering me and so many other Canadians: The totally unacceptable insults and unprecedented threats to our very sovereignty from U.S. president-elect Donald Trump. I have two very clear and simple messages. To Donald Trump, from one old guy to another: Give your head a shake! What could make you think that Canadians would ever give up the best country in the world – and make no mistake, that is what we are – to join the United States? I can tell you Canadians prize our independence. We love our country. We have built something here that is the envy of the world – when it comes to compassion, understanding, tolerance and finding a way for people of different backgrounds and faiths to live together in harmony. We’ve also built a strong social safety net – especially with public health care – that we are very proud of. It’s not perfect, but it’s based on the principle that the most vulnerable among us should be protected. This may not be the “American Way” or “the Trump Way.” But it is the reality I have witnessed and lived my whole long life. If you think that threatening and insulting us is going to win us over, you really don’t know a thing about us. You don’t know that when it came to fighting in two world wars for freedom, we signed up – both times – years before your country did. We fought and we sacrificed well beyond our numbers. We also had the guts to say no to your country when it tried to drag us into a completely unjustified and destabilizing war in Iraq. We built a nation across the most rugged, challenging geography imaginable. And we did it against the odds. We may look easy-going. Mild-mannered. But make no mistake, we have spine and toughness. And that leads me to my second message, to all our leaders, federal and provincial, as well as those who are aspiring to lead our country: Start showing that spine and toughness. That’s what Canadians want to see – what they need to see. It’s called leadership. You need to lead. Canadians are ready to follow. I know the spirit is there. Ever since Mr. Trump’s attacks, every political party is speaking out in favour of Canada. In fact, it is to my great satisfaction that even the Bloc Québécois is defending Canada. But you don’t win a hockey game by only playing defence. We all know that even when we satisfy one demand, Mr. Trump will come back with another, bigger demand. That’s not diplomacy; it’s blackmail. We need another approach – one that will break this cycle. Mr. Trump has accomplished one thing: He has unified Canadians more than we have been ever before! All leaders across our country have united in resolve to defend Canadian interests. When I came into office as prime minister, Canada faced a national unity crisis. The threat of Quebec separation was very real. We took action to deal with this existential threat in a manner that made Canadians, including Quebeckers, stronger, more united and even prouder of Canadian values. Now there is another existential threat. And we once again need to reduce our vulnerability. That is the challenge for this generation of political leaders. And you won’t accomplish it by using the same old approaches. Just like we did 30 years ago, we need a Plan B for 2025. Yes, telling the Americans we are their best friends and closest trading partner is good. So is lobbying hard in Washington and the state capitals, pointing out that tariffs will hurt the American economy too. So are retaliatory tariffs – when you are attacked, you have to defend yourself. But we also have to play offence. Let’s tell Mr. Trump that we too have border issues with the United States. Canada has tough gun control legislation, but illegal guns are pouring in from the U.S. We need to tell him that we expect the United States to act to reduce the number of guns crossing into Canada. We also want to protect the Arctic. But the United States refuses to recognize the Northwest Passage, insisting that it is an international waterway, even though it flows through the Canadian Arctic as Canadian waters. We need the United States to recognize the Northwest Passage as being Canadian waters. We also need to reduce Canada’s vulnerability in the first place. We need to be stronger. There are more trade barriers between provinces than between Canada and the United States. Let’s launch a national project to get rid of those barriers! And let’s strengthen the ties that bind this vast nation together through projects such as real national energy grid. We also have to understand that Mr. Trump isn’t just threatening us; he’s also targeting a growing list of other countries, as well as the European Union itself, and he is just getting started. Canada should quickly convene a meeting of the leaders of Denmark, Panama, Mexico, as well as with European Commission President Ursula von der Leyen, to formulate a plan for fighting back these threats. Every time that Mr. Trump opens his mouth, he creates new allies for all of us. So let’s get organized! To fight back against a big, powerful bully, you need strength in numbers. The whole point is not to wait in dread for Donald Trump’s next blow. It’s to build a country and an international community that can withstand those blows. Canadians know me. They know I am an optimist. That I am practical. And that I always speak my mind. I made my share of mistakes over a long career, but I never for a moment doubted the decency of my fellow Canadians – or of my political opponents. The current and future generations of political leaders should remember they are not each other’s enemies – they are opponents. Nobody ever loved the cut-and-thrust of politics more than me, but I always understood that each of us was trying to make a positive contribution to make our community or country a better place. That spirit is more important now than ever, as we address this new challenge. Our leaders should keep that in mind. I am 91 today and blessed with good health. I am ready at the ramparts to help defend the independence of our country as I have done all my life. Vive le Canada! (Article shared by Steve Paikin) See less"
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Excited to see the PhD work led by Sarah Danchuk published today at @PNASNews . Virulence hierarchies within the Mycobacterium tuberculosis complex. Thanks to all the authors and collaborators, and especially kudos to Sarah: pnas.org/doi/10.1073/pnas.25…. .
Sarah Danchuk summarizes differences between M. bovis infections and M. orygis infections at her brilliant PhD defence. Two slides, two outcomes.
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When food is wasted, so are the resources used to produce it, including #water, energy, and labour. Minimize what you throw away. Explore #FoodWaste prevention tips: ow.ly/4FCr50X677t @CEMonthCanada @CircularOnline
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Jeffrey Chen retweeted
We're about to create the 1st gen of scientists who can't research without AI. And honestly? I'm not sure if that's evolution or devolution! 𝗦𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁𝘀 𝗮𝗿𝗲 𝗻𝗼𝘄 𝘂𝘀𝗶𝗻𝗴 𝗖𝗵𝗮𝘁𝗚𝗣𝗧 𝘁𝗼: — Extract key findings from dense papers in seconds — Design entire experiments from scratch — Turn complex studies into engaging content for public — Generate survey questionnaires that would take days to create — Respond to peer reviewers (yes, really) & this book does a great job going through these details! But missed the elephant in the room: ⤴️ research inequality. Universities with AI access will accelerate faster than those without. Researchers fluent in prompt engineering will outpace those who aren't. We're creating new divides in an already unequal system! It doesn't address how AI might bias research directions: ⤴️ We're training AI on biased research. Now it's teaching us. See the problem? Overall, this isn't another "AI will save us all" book. Authors actually tested ChatGPT on real research tasks & documented both the wins and the spectacular failures. 𝐌𝐲 𝐭𝐚𝐤𝐞𝐚𝐰𝐚𝐲: We need AI-literate researchers, not AI-dependent ones! 💬 𝗪𝗵𝗶𝗰𝗵 𝗮𝗿𝗲 𝘄𝗲 𝗰𝗿𝗲𝗮𝘁𝗶𝗻𝗴? Comment if you'd like a link to download this book! ------------------------- Useful find? Pass it on! 🔄 Retweet 👋 I’m @RaziaAliani Click my name + follow + 🔔 I post about AI in #research & #analysis Want FREE tips on using AI in research? ↳ Join 15K+ researchers: 🔗 link in bio ----------------------- #aiinresearch
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In doing so, this talented young scientist discovered 1) a novel activator of ESX-1 gene transcription and 2) a novel vaccine that is as protective as BCG but does not compromise existing TB diagnostic tests.
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Jeffrey Chen retweeted
VIDO is building a new animal housing facility that will expand our research capacity—housing everything from mosquitoes to ticks to bats🦟🕷️🦇. These vectors are crucial for disease spread, and access to them will help us better prepare for emerging threats. #VIDOis50
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Jeffrey Chen retweeted
New TB research! 🧫 A collab between VIDO & UBC shows the Parkinson’s drug benztropine may help immune cells fight TB. VIDO confirmed it works in infected mice using our CL3 labs. Great example of shared expertise in action. 🔗 nature.com/articles/s44259-0… #TBResearch #usask #ubc
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Jeffrey Chen retweeted
In 50 days, VIDO will celebrate its 50th anniversary!! 🎉 Follow along as we count down by sharing a daily fact about VIDO’s evolution and innovations over the past five decades! #VIDOis50
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Jeffrey Chen retweeted
Our paper is out! The Parkinson’s drug benztropine possesses histamine receptor 1-dependent host-directed antimicrobial activity against Mycobacterium tuberculosis. Thanks @henok_sahile and team for your great work. #repurposing @UBC #TB #HDT rdcu.be/ezA77
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📣We have decided to extend the application deadline for LMIC and non-LMIC awards to April 7th! Please help us spread the word and share the updated flyers within your networks on social media? Applications can be submitted via the ISV Congress website isvcongress2025.co.za
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Eliminating tuberculosis in Canada IS within reach if we work together. Read our statement for #WorldTBDay to learn how we are working with Indigenous and government partners to achieve this goal: ow.ly/3T8u50VnxKC
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This #WorldTBDay, we stand in solidarity with the millions who are affected or lose their lives because of tuberculosis every year. The effort to #EndTB is urgent. Global health budgets are being cut around the world and TB rates right here in Canada are rising. Thanks to our volunteers, a record ✨51 monuments📷 will be lit up in red TODAY in every province to raise awareness for TB. These lights serve as a call-to-action for decision-makers to take action to eradicate TB at home and abroad. Plan an outing tonight to a monument near you to help shine a 📷resultscanada.ca/action-butt…… Show up and show your support! #YesWeCanEndTB
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Our @unizar colleagues, Ainhoa, Cris and Santi, were on TV today for #WorldTBDay2025 discussing publications on new compounds, the Hollow Fibre system, integration of AI in clinical trials and the upcoming public plenaries at our general assembly in May!
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Jeffrey Chen retweeted
🎙️On #WorldTBDay, VIDO scientist Dr. Jeffrey Chen @JeffChenMycoLab joined @600CJWW to share how his lab is advancing vaccine research to #EndTB. Learn how VIDO is driving innovation to protect global health. #vaccines #InfectiousDisease #OneHealth @USaskresearch

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Good to have you back.
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