@JaulinLab

The cell biology of cancer Institut Gustave Roussy France

Joined May 2020
Replying to @JaulinLab
Thanks to all our collaborators!! Here is the link to the study: science.org/doi/10.1126/scia… Now stay tuned for the follow-up 🤓… (5/5)
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Les avatars biologiques et numériques vont jouer un rôle crucial pour passer d'une médecine empirique à une médecine d'ultra-précision; @GustaveRoussy et ses chercheurs créent Orakl, une start-up qui ambitionne de délivrer un service sur mesure partout et pour tous #PSCC
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Super cool to see our data featured alongside work from @mayor_lab on the prestigious lecture series of @cdf1530 by @LecuitLab. Super interesting to see the take of a top scientist and how it integrates into the common knowledge on cell migration 🙏🏼🤩 college-de-france.fr/agenda/…
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Bravo à tous nos chercheurs et médecins qui se mobilisent pour déployer des technologies de rupture pour soigner ces cancers!
[Journée mondiale du #cancerdupancréas] Zoom sur un organoïde de pancréas sous 🔬🔎x60 qui testera les médicaments à notre place, afin de choisir le plus adapté pour chaque #patient. Une innovation au cœur de l’étude ORGANOTREAT Pancréas qui débutera en 2023 à @GustaveRoussy
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[Journée mondiale du #cancerdupancréas] Zoom sur un organoïde de pancréas sous 🔬🔎x60 qui testera les médicaments à notre place, afin de choisir le plus adapté pour chaque #patient. Une innovation au cœur de l’étude ORGANOTREAT Pancréas qui débutera en 2023 à @GustaveRoussy
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📣 JOB ALERT!! 🔬 Time to get into the details of amoeboid #collectivemigration! 3 years funded postdoc position in collaboration with @PielMatthieu, @mcoppey and Voituriez labs to decrypt the cellular and molecular mechanisms of CAM (science.org/doi/10.1126/scia…)
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Great that our paper made the cover. Thank you @CD_AACR! Thanks to the team (those on twitter: @YasongYuMD @powersann3 @evakiani @Gusain_Laxmi @annalisa_ub @eck405 @andrea_marcadis ) and collaborators @TheVinodLab, B Reva and K Jessen.
Check out the paper featured on the cover of this month’s Cancer Discovery: Reprogrammed Schwann Cells Organize into Dynamic Tracks that Promote #PancreaticCancer Invasion, by @sylvie_deborde, Richard Wong et al. bit.ly/3SRumnq @MSKCancerCenter
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“Cell clusters adopt a collective amoeboid mode of migration in confined nonadhesive environments” 🔬 New study led by @JaulinLab, @DornierEmmanuel, @PagesDianeLaure published in the latest issue of @ScienceAdvances 👉 science.org/doi/10.1126/scia…
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Ever found weird that collectives can only do one thing to move? We did🤓 Turns out they don’t. As single cells do, clusters have a spectrum of motility modes to play with!! An amazing discovery and my first co-corresponding paper 🤩 More to come on the topic… 😁
📣New study 📣 Led by @DornierEmmanuel and @PagesDianeLaure, in collaboration with @PielMatthieu, @mcoppey and Voituriez labs. We describe a second mode of collective migration relying on a mechanism never shown before, allowing cancer collectives to move without adhesions 🧵👇🏼
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📣New study 📣 Led by @DornierEmmanuel and @PagesDianeLaure, in collaboration with @PielMatthieu, @mcoppey and Voituriez labs. We describe a second mode of collective migration relying on a mechanism never shown before, allowing cancer collectives to move without adhesions 🧵👇🏼
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This jiggling is tightly correlated to cell deformations and cluster speed. Nevertheless, it requires the actomyosin polarization to foster directed migration. We called this new mode of collective migration “Polarised jiggling” (4/5)
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Happy to present our most recent published paper, in @J_Cell_Sci : journals.biologists.com/jcs/… "Patient-derived organoids identify an apico-basolateral polarity switch associated with survival in colorectal cancer" by @CanetJourdan and colleagues 🎉 #cancerscience
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Beautiful work by @CanetJourdan involving epithelial polarity, actomyosin, TGFß and integrins in CRC PDOs. This publication also involves @ValeriaBarresiS @DucreuxMichel @PagesDianeLaure @JB_R_LOPEZ and other great collaborators. #cellbiology #journalofcellscience
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We are still searching for a PhD student to work on the reconstitution of the mechanism regulating microtubule aster shape and position. In few days our 3-year fellowship will be lost... DM me or @Lblanchoin if you are interested.
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🌍3 members of our lab are present at @IBECBarcelona-@EMBLBarcelona winter conference "Engineering Multicellular Systems" @PagesDianeLaure will talk Thursday 9th at 11:45am @JB_R_LOPEZ & E.Gontran joined by @GiuliaFornabaio from IBEC present poster n°16 Come see us ! #EIWConf 🔬
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Super cool poster session during lunch for our team ☀️ "Mechanisms of biogenesis of a novel tumoral intermediate in CRCs" created many interesting discussions ! @GiuliaFornabaio @JB_R_LOPEZ & Emilie Gontran 🤟 #EIWConf @EMBLBarcelona @IBECBarcelona
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