@JaneDoesScience

MB/PhD student @MRC_LMB 👩‍🔬👩‍🏫 Interested in immunology, natural killer cells and how we can use them to fight cancer

Joined September 2021
  • Tweets13
  • Following64
  • Followers27
2Media
Jane Murphy retweeted
NHLI@ImperialNHLI20 Jan 2023
We welcome Dr @gogoimayuri to #NHLI to give a talk on 'ILC2-derived LIF: a novel regulator of pulmonary allergen and viral induced immune response' 📆 Monday 30 January at 12:30 - hybrid event at South Kensington and on Teams Details: imperial.ac.uk/events/157243…
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Jane Murphy retweeted
aydanszeto@aydanszeto23 Dec 2022
1/ CRISPR screen, IL-13, T helper-2 cells and integrins – what’s the connection? We have reported our findings in @NatImmunol . Also check out this helpful article written by our institute @MRC_LMB without all the scientific jargon (www2.mrc-lmb.cam.ac.uk/integ…).
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Elated to see the fruits of the @MeierLabICR + Aebersold lab collaboration and my 1st co-first author paper out! Valiant effort from twitterless Roldof Ciuffa and @federico_uliana & all co-authors for getting this out! 1/3 pnas.org/doi/10.1073/pnas.21…

Novel biochemical, structural, and systems insights into inflammatory signaling revealed by...

Protein–protein interactions (PPIs) represent the main mode of the proteome organization in the cell. In the last decade, several large-scale repre...

pnas.org
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Also very greatful to @A_Zebboudj, Masataka Amisaki and @TheVinodLab for this comprehensive & insightful Focus: science.org/doi/10.1126/scii… 8/8

ILC2s—Bipartisan politicians in cancer

Group 2 innate lymphoid cells (ILC2s) are lymphocytes that both promote and suppress antitumor immunity.

science.org
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Amazing job by @Ana_CFF, @JonathanMannio1, @Michelle_cKO, @JaneDoesScience, Paula Clarck & Helen Jolin from the McKenzie lab @MRC_LMB, our collaborators @SiBucz & others from the @stemcell, & @lifearc1. I'm very thankful to Eric & Andrew for including me in this project! 2/
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Delighted to see this manuscript out @SciImmunology! Kudos to twitterless Eric Jou for this work! An innate IL-25–ILC2–MDSC axis creates a cancer-permissive microenvironment for Apc mutation–driven intestinal tumorigenesis science.org/doi/10.1126/scii… 🧵1/

An innate IL-25–ILC2–MDSC axis creates a cancer-permissive microenvironment for Apc mutation–driven...

IL-25–activated ILC2s establish an immunosuppressive niche for CRC tumorigenesis by suppressing IFN-γ–mediated antitumor immunity.

science.org
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So, who wants to be our next colleague? Core funded tenure track position available @MRC_LMB in Cambridge (UK) for a scientist working on mechanistic aspects of immunology or host-pathogen interactions. Pls retweeet. nature.com/naturecareers/job…
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