Applied physicist & optical microscopist/microscopologist
Joined September 2019
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James Manton retweeted
Interested in working on a state-of-the-art connectomics pipeline at its birthplace as a postdoc? We’d love to hear from you! :)
mrc.tal.net/vx/mobile-0/appc…
James Manton retweeted
I have two job adverts open at the minute:
- A PhD position on fast MLIPs for biomolecules (www2.mrc-lmb.cam.ac.uk/stude…)
- A postdoc position on developing a universal molecular mechanics force field (nature.com/naturecareers/job…)
Feel free to get in touch with questions.
James Manton retweeted
Two available postdoc scholarships at Norlin Lab in Lund!
1. Optical Engineering: OPM/light-sheet microscopy and lensless imaging jobrxiv.org/job/lund-univers…
2. Flexible Position: Related to spatial-omics method development or LLMs for life science research. Email/DM if interested
James Manton retweeted
If you find these kind of incisive scientific discoveries - fluorescence microscopy is not cat photos - interesting then please come and work with me on the project! Details here, deadline 11 November -> kcl.ac.uk/jobs/097465-postdo…
Beware of applying computer-vision metrics to microscopy image of biological samples. At best, you fool only yourself.
@SuperResoluSian #I2K2024 #BioImageAnalysis
James Manton retweeted
Our lab @MRC_LMB is seeking a passionate PhD student to explore transcription-coupled splicing! Join our team for an exciting project to understand human gene regulation 🧬 Feel free to get in touch directly #PhD #cryoEM #biochemistry
James Manton retweeted
We will have multiple opening (PhD, postdocs) in the near future, across all themes of the group. Get in touch if you’re interested !
James Manton retweeted
Job adverts are now live: FLIM/optics/data processing: jobs.ac.uk/job/DJL002/resear… CLOSING SOON. Cardiac microscopy, data processing and open hardware tech scale-up: jobs.ac.uk/job/DJK837/resear…. We welcome applicants from backgrounds traditionally underrepresented in physics [contd...]
James Manton retweeted
Have you ever wanted to measure oligomers in living cells?🙂
New BTS method from @FritzscheLab @faldalf @KaredlaNarain @pfcespedes @MichaelLDustin
nature.com/articles/s41467-0…
James Manton retweeted
Superresolution microscopy at sub zero temperature: 2 year post doc position available in @group_laser in @cebcambridge and @BAS_News doc to build instruments to study life in the Antarctic. 🔬🥶🐟🧑🔬 jobs.cam.ac.uk/job/48053/
NEW JOB: Postdoc Research Associate to work alongside the British Antarctic Survey on a game-changing project aiming to develop high-resolution microscopes to study biological processes at sub-zero temperatures.
For more information and to apply: jobs.cam.ac.uk/job/48053/
James Manton retweeted
Apply now as Max Planck Research Group Leader (W2) in Cell Biology @mpicbg! Details and application: mpi-cbg.de/join-us/open-posi…
James Manton retweeted
Thrilled to share our latest story @NatureCellBio on a new way to control protein localization without exogenous triggers (e.g., light/rapamycin)—take advantage of endogenous triggers in dividing cells!
Free link: rdcu.be/dSlrS Regular link: nature.com/articles/s41556-0… 1/4
James Manton retweeted
Exciting grant news in the pipeline - we will be recruiting THREE physics/engineering postdocs in Glasgow with skills in optics/microscopy/FLIM/realtime imaging & data processing, to start between oct & jan. Various projects in live 🐟💓🔬, building new tools to image […] 1/2
James Manton retweeted
Check out this fantastic opportunity in the McDole lab here at the LMB. Right at the interface of imaging and development!
James Manton retweeted
Can anyone recommend any good resources for learning about inverse problems in general, preferably catered to experimentalists?
I'm trying to compile a "toolbox" of what's available, but I'm finding specialist literature too technical.
James Manton retweeted
Since long time we tried to achieve “permanent” labelling of plasma membranes. Now it become possible with MemGraft probes, which exploit a new principle of lipid-directed covalent fluorescent labeling of membrane proteins. The MemGraft probes are compatible with fixation, permeabilization, trypsinization, presence of serum in the medium and enable long-term cell imaging, co-culture of cells and their imaging in multiple colors, cell barcoding and cell manipulation. Congrats and thanks to co-authors: Nathan Aknine @n_aknine & Remi Pelletier. @unistra @CNRS @CNRS_Alsace @LBP_Illkirch
Just out in biorXiv:
biorxiv.org/content/10.1101/…
James Manton retweeted
Out in Nat Meth!
Try it out and give us feedback!
Code available on github.
Happy to answer all questions!
Thanks to @naturemethods and @rita_strack for smooth review process.
Big 🙏 to @LanceWQXu1 @NilsWalterLab, @SgouralResearch , @zelihakilicc
Bayesian nonparametric Track (BNP-Track) simultaneously determines emitter numbers and their tracks alongside uncertainty, extending the super-resolution paradigm from static samples to single-particle tracking even in dense environments. @LabPresse nature.com/articles/s41592-0…
James Manton retweeted
🚨🔔🚨 We have another postdoc opening in our group to study lipid trafficking in neurons. If you have a background in mechanistic cell biology and lipids (lipidomics= bonus!) and are interested in employing your skills in neurons- Apply! Link below - closes 22nd July. please RT!
James Manton retweeted
🔬🤖Excited to share permittivity tensor imaging (PTI), a label-free computational imaging module for high-resolution 3D imaging of dry mass and 3D orientation of organelles, cells, and tissues! 🧬🧫
Just published in @naturemethods
nature.com/articles/s41592-0…
Shout out to @LiHao_Yeh , @TalonChandler, @ieivanov1, @janie00, @BryantChhun , @symguo, @CameronFoltz at @czbiohub, Peter Kazansky lab @orctweets, @BruceConklin lab at @GladstoneInst, and May Han lab at @StanfordMed.
🧵1/n
James Manton retweeted
I have been fooled by such images. They very much suggest that the balance of pulling forces along microtubules center the array.
...
James Manton retweeted
@MegDrisc, Erik Welf, @MuthrNaturzSon , @kD3AN, @DanuserLab et al describe "worrying" as a mode of cell migration; melanoma cells literally dig tunnels.
The paper is out, combining cancer cell bio, computer vision (u-shape3D) and 3D microscopy:
authors.elsevier.com/c/1jFOh…