@JakeMont12

Postdoc @uchicago trying to understand how weeds adapt and evolve with @jmKreiner. Views and spelling are my own.

Joined November 2013
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  • Following194
  • Followers258
9Media
Out this week in Weed Technology, a paper describing the project I helped with while I was an intern at @Bayer. Read the full story here cambridge.org/core/journals/…. I usually don’t do these threads, but here goes nothing. 1/7

Distribution of target site PPO-inhibiting herbicide resistance mutations in waterhemp and Palmer...

Distribution of target site PPO-inhibiting herbicide resistance mutations in waterhemp and Palmer amaranth and association of epyrifenacil efficacy with PPX2 target site variants - Volume 39

cambridge.org
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This supports other experiments that suggest epyrifenicil will be able to control weeds that are resistant to some other PPO-inhibiting herbicides like lactofen or fomesafen. We found some new mutations, but these are tightly linked with G210 and are probably not important. 6/7
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This was a really fun project for me and it gave me an opportunity to work with some great folks at Bayer where they are trying to combat herbicide resistant weeds every day. If you made it this far, thanks for reading my first paper thread! 7/7
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Keith Slotkin@Slotkin_Lab6 Jun 2025
Latest work from the lab led by @yuhunghung in @ThePlantJournal! We engineered a RNA-binding protein to sort and protect a Cas9 transcript for long term expression! Can be applied to any engineered transcript as a UTR: onlinelibrary.wiley.com/doi/…

Engineering an RNA/protein‐binding module for higher transgene protein production and improved...

The low efficiency of transgene performance extends the long and expensive crop improvement pipeline, as well as hampers efforts to research the fundamental mechanisms of plant biology. We provide a...

onlinelibrary.wiley.com
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Following the firing of thousands of young USDA scientists yesterday, I will no longer be posting on this platform. You can find me on LinkedIn and Instagram.
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clara T@ramencult10 Feb 2025
New preprint! We find a novel signal of positive selection in georeferenced genotype data, then use this signal to identify in-progress selective sweeps in the malaria vector Anopheles gambiae: biorxiv.org/content/10.1101/…

Sweeps in space: leveraging geographic data to identify beneficial alleles in Anopheles gambiae

As organisms adapt to environmental changes, natural selection modifies the frequency of non-neutral alleles. For beneficial mutations, the outcome of this process may be a selective sweep, in which...

biorxiv.org
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WSSA | GSO@WSSA_GSO4 Feb 2025
Right after the WSSA GSO Student Luncheon, we’ve got an exciting Panel Discussion lined up! Hear firsthand insights from experts across industry, academia, and government—perfect for anyone looking to grow their network and gain fresh perspectives. Bring your questions! 🙌
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WSSA | GSO@WSSA_GSO4 Feb 2025
🚨 WSSA Student in-person Webinar! 🚨 Dive into Protein Modeling of Herbicide Resistance 🧬🌿 🗓️ Feb 25 ⏰ 4:45 💻 Bring your laptop & download pyMOL before the workshop! [pymol.org/2/]
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Rasmus Nielsen@ras_nielsen24 Jan 2025
CASTER: Direct species tree inference from whole-genome alignments. Super proud to have made small contributions to this incredibly clever work by the amazing Chao Zhang and his PhD advisor S. Mirarab. science.org/doi/10.1126/scie…

CASTER: Direct species tree inference from whole-genome alignments

Genomes contain mosaics of discordant evolutionary histories, challenging the accurate inference of the tree of life. Although genome-wide data are routinely used for discordance-aware phylogenomic...

science.org
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New episode is available! This week we have Dr. Todd Gaines on to talk about some novel genetic methods to control weeds. He covers the evolution of genomics and how it's helping scientists understand and combat herbicide resistance. Thanks for listening!
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Keith Slotkin@Slotkin_Lab4 Dec 2024
The Slotkin lab is hiring for an exciting project that involves gene editing, transposable elements and plant transformation! Please RT! paycomonline.net/v4/ats/web.…
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Will Ratcliff
@wc_ratcliff26 Oct 2024
New preprint up! We sequenced hundreds of samples from across one of Earth's oldest living organisms - the Pando aspen clone - to understand how mutations accumulate and spread in long-lived clonal organisms. Our results were…surprising. 1/30
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Samuel Hume
@DrSamuelBHume18 Oct 2024
Biggest medical discoveries of the week (🧵) 1/8 An engineered insulin, NNC2215, whose activity is adjusted by glucose concentration Its affinity for the insulin receptor drops >3-fold when glucose levels fall - reducing the risk of hypoglycaemia nature.com/articles/s41586-0…
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Kenny Workman
@kenbwork18 Oct 2024
Many new machine learning tools for protein engineering have popped up in the last year. In these early days, it might be unclear how to actually use them for real molecular design tasks in industry. We demonstrate how to engineer a cholesterol drug and plastic degrading enzymes in detail. 1\N
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Curious about how major weed species are related? I published this phylogeny of ALS gene sequences from all the species currently hosted on WeedPedia along with the story of the international Weed Genomics Consortium. Check it out: doi.org/10.1564/v35_aug_02
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Characterization of a novel eccDNA carrying both glyphosate and glufosinate target site due to co-duplication of their chromosomic native region - @theweednaldo @CuttiLuan @AimonePorri Ingo Meiners, Jens Lerchl, @GenomEric @NorsworthyJason
bioRxiv Genomics@biorxiv_genomic13 Oct 2024
A Novel Genomic Rearrangement in the Amaranthus palmeri Extrachromosomal Circular DNA Provides Dual Herbicide Resistance to ... biorxiv.org/cgi/content/shor… #biorxiv_genomic
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