Postdoc @BrainMind_USYD Emerging Leadership Fellow @NHMRC Exec Editor, @CUP_RDirections Depression Mental health, circadian clocks, early intervention
Sydney, Australia
Joined May 2017
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What do clinicians need to know about chronobiology & chronotherapeutics to support their care of people with bipolar disorders?
Our international expert consensus study has distilled 50 years of research into the “must know” information for clinicians.
onlinelibrary.wiley.com/doi/…
Jake Crouse retweeted
Among adults with #Depression, complex antidepressant treatment patterns were associated with higher polygenic risk for psychiatric traits but not with sustained use of a single antidepressant. ja.ma/4qNcRFW
ALT Figure 1. shows Antidepressant Use of the Australian Genetics of Depression Study (AGDS). Graph A shows number of participants with recorded antidepressant dispense. Graph B shows distribution of cumulative prescription duration per antidepressant.
Jake Crouse retweeted
Among adults with #Depression, complex antidepressant treatment patterns were associated with higher polygenic risk for psychiatric traits but not with sustained use of a single antidepressant. ja.ma/4k7CI99
New in @JAMAPsych - in the Australian Genetics of Depression Study we show using 4.5 yrs of prescription data that genetic risk for ADHD, depression, neuroticism and bipolar disorder influence the complexity of an individual's depression treatment journey
jamanetwork.com/journals/jam…
Jake Crouse retweeted
Our new paper in Biological Psychiatry (@SOBP) in 3,000 Australians with atypical depression (N=15K) links atypicality with poorer response to SSRIs and SNRIs + genetic risk for metabolic, inflammatory, and circadian traits.
@ian_hickie
@mirim_shin
biologicalpsychiatryjournal.…
Our new paper in Biological Psychiatry (@SOBP) in 3,000 Australians with atypical depression (N=15K) links atypicality with poorer response to SSRIs and SNRIs + genetic risk for metabolic, inflammatory, and circadian traits.
@ian_hickie
@mirim_shin
biologicalpsychiatryjournal.…
Jake Crouse retweeted
🆕Comment| Insulin resistance as an early marker in youth with mood disorders.
@mirim_shin, @ian_hickie, @Sydney_Uni, @AarhusUni_int
nature.com/articles/s44220-0…
Jake Crouse retweeted
From the hosts @ian_hickie and @Jamesologhlin of the popular #MindingYourMind podcast comes an empowering book that examines the key moments in our mental health journey.
📖 - bit.ly/UsersGuidetotheMind
🎙️ - bit.ly/46RlFDB
@syd_health
Jake Crouse retweeted
Our latest paper showing evidence for internal circadian misalignment in mood disorders! doi.org/10.1177/074873042513… A thread🧵:
@ian_hickie
@JacobJCrouse
@Zsofi_deHaan
@mirim_shin
@emilianatonini
@frankiorfino
@BrainMind_Usyd
@Sydney_Uni
@SageJournals
@SRBR_Outreach
Jake Crouse retweeted
Exciting Leadership Opportunity - Applications are open for role of Co-Director, Brain and Mind Centre at the @Sydney_Uni #LeadershipforGood
☑️ Find out more and apply here: lnkd.in/gUGmJSfn
@ian_hickie @Kathy_Refshauge @KathyBelov @syd_health @Sydney_Science
Jake Crouse retweeted
Great turnout for Mid-Year event in the courtyard with heaters 🔥
It's been an amazing 6 months of 2025 with Co-directors @ian_hickie noting our achievements so far! Researchers @frankiorfino @JacobJCrouse spoke on their team's achievements!
@syd_health @HBAProgram_USYD
Jake Crouse retweeted
More evidence linking #depression & #daylight 🌞
In 13,000 Australians with depression, more time in daylight was associated with better sleep and mental health (adjusting for genetic risk, season, etc)
#sleep #circadian
@ian_hickie @Euro_Psychiatry
bit.ly/4ei9th5
More evidence linking #depression & #daylight 🌞
In 13,000 Australians with depression, more time in daylight was associated with better sleep and mental health (adjusting for genetic risk, season, etc)
#sleep #circadian
@ian_hickie @Euro_Psychiatry
bit.ly/4ei9th5
Jake Crouse retweeted
Thanks to Heston Blumenthal for making Heston: My Life with Bipolar. Honest and intelligent programme and an excellent insight into life with the condition and difficulties balancing medication effects. An unselfish man, he’s moved by the stories of others bbc.co.uk/iplayer/episode/m0…
Jake Crouse retweeted
🚨Research Assistant job at @OxPsychiatry with @WrayNaomi and myself to start!
Ideal opportunity to gain experience in Psychiatric Genomics working on clinically impactful projects
👉lnkd.in/gKq3TgvQ
Please repost!
Jake Crouse retweeted
Check out our Topic Collection on Chronopsychiatry now available on BMJ Mental Health. #circadian #sleep #MentalHealth mentalhealth.bmj.com/pages/c…
Jake Crouse retweeted
Giving a talk next week presenting some new work on algorithmic fairness. Online so come along if you can!
Join our next Prediction Modelling presentation with Dr @Dom__Oliver @KingsIoPPN on assessing bias in a transdiagnostic risk calculator for #psychosis.
🗓️Wednesday 28 May, 15:00 - 16:00, Online
kcl.ac.uk/events/algorithmic…
ALT Are our predictions fair? Assessing and addressing algorithmic bias in a transdiagnostic risk calculator for psychosis
Jake Crouse retweeted
Our work with the Daymark Foundation has resulted in a new paper on what the experts say about early intervention for bipolar disorder @JacobJCrouse @KateFilia @MonashPsych @orygen_aus
onlinelibrary.wiley.com/doi/…
Jake Crouse retweeted
Grateful to have played a small part in this letter published in World Psychiatry (@WPA_Psychiatry)
We identify 9 challenges to advancing early intervention in #bipolardisorders and hope to galvanise action to these issues
onlinelibrary.wiley.com/doi/…
Grateful to have played a small part in this letter published in World Psychiatry (@WPA_Psychiatry)
We identify 9 challenges to advancing early intervention in #bipolardisorders and hope to galvanise action to these issues
onlinelibrary.wiley.com/doi/…