@JacksonLitteken

Former student in the @JonBb7 lab at UAMS and post-doc in the @MarioFeldman9 at WashU. My lab at UAMS studies pathogenic mechanisms of Acinetobacter infection.

 Little Rock, AR
Joined November 2018
  • Tweets73
  • Following280
  • Followers159
2Media
Looking forward to my visit. Excited to catch up with friends and colleagues, and to meet new and amazing microbiologists!! See you there!
Jorge E. Vidal@JorgeEVidal1Jun 10
Save the Date! The South Central Branch of the @ASMicrobiology is hosting its Annual Meeting in Hot Springs, Arkansas! Big thanks to the UAMS organizing committee, including Dr. Clay Jackson-Litteken. Excited to welcome our Keynote Speaker: Dr. Shaun Brinsmade! More details soon
1
1
6
530
The new PhD candidate Lidia presenting her work on Acinetobacter baumannii adhesins!
7
115
My first (and awesome) student, Lidia Belete, presenting her work!
1
61
Congrats Manon! Glad I could be a part of it!
This Post is from a suspended account. Learn more
69
Jackson-Litteken Laboratory retweeted
Mario Feldman@MarioFeldman928 Sep 2025
Happy to share the last pre-print of the lab, just in time for the phD defense of Evan!! Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in Bacteroides thetaiotaomicron biorxiv.org/content/10.1101/…

Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in Bacteroides...

Bacteroides spp. are Gram-negative, gut commensals that shape the enteric landscape by producing outer membrane vesicles (OMVs) that degrade dietary fibers and traffic immunomodulatory biomolecules....

biorxiv.org
4
10
499
Congrats Alexis!
Mario Feldman@MarioFeldman929 Sep 2025
I said I will never work on phages, but having Michele Leroux next door made me change my mind. Here is Alexis's new paper showing how different phages deal with the capsular barrier to infect Acinetobacter! journals.plos.org/plospathog…

Acinetobacter phages use distinct strategies to breach the capsule barrier

Author summary Acinetobacter baumannii causes life-threatening and often antibiotic-resistant infections thereby posing a global threat. Accordingly, there is an urgent need for alternative treatme...

journals.plos.org
60
Great to see this out! Thanks @MarioFeldman9 for your mentorship!
Mario Feldman@MarioFeldman921 Aug 2025
Happy to share the latest paper of my lab. Congrats to now professor Clay Jackson-Litteken and everyone involved! nature.com/articles/s41467-0…

A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic...

Nature Communications - Here, the authors develop a chronic murine model of Acinetobacter baumannii pulmonary infection that overcomes some limitations of acute models and allows investigation of...

nature.com
3
150
Jackson-Litteken Laboratory retweeted
Mario Feldman@MarioFeldman929 Apr 2025
Yes! @manon_janet preprint is out! We show using BALF transfer that an intracelular Acinetobacter clinical strain can seed an infection in a susceptible mouse, suggesting that intracellular bacteria may be reservoir for recurrent infections 1/2 nam10.safelinks.protection.o…
1
5
1
16
1,416
Thank you @MarioFeldman9 for everything! You are an amazing mentor and I will miss y'all!
Mario Feldman@MarioFeldman924 Nov 2024
Saying good bye to @JacksonLitteken who is going to fly solo and start his lab in Little Rock. We are going to miss you!!!
3
17
1,146
Happy to share this paper from some of my graduate work! It was a great team effort with several current and former members of the @@JonBb7 lab!
UAMS Microbiology & Immunology@UAMSMicroImmuno23 Jul 2024
Congratulations to the Blevins lab for their new publication at @PLOSNTDs! @JonBb7 @JacksonLitteken @votheroski @UAMS_COM journals.plos.org/plosntds/a…

Development and validation of systems for genetic manipulation of the Old World tick-borne relaps...

Author summary Relapsing fever is a globally distributed, vector-borne bacterial infection that is characterized by recurring febrile episodes. The causative Borrelia spp. were identified over 100...

journals.plos.org
2
1
11
771
Jackson-Litteken Laboratory retweeted
Mario Feldman@MarioFeldman922 Mar 2024
Excited to announce that the 14th International Acinetobacter conference (and first in North America!) will take place in Niagara Falls on July 6-10 2025 in collaboration with @FASEBorg. More info to follow. #FasebAcinetobacter
2
23
4
65
12,803
Come join a great lab!
Mario Feldman@MarioFeldman930 Nov 2023
An NIH-funded postdoctoral position is available in my lab to work on Acinetobacter pathogenesis. WashU is great, St Louis is an affordable and cool city. Info is below.....please RT.
4
8
1,090
Jackson-Litteken Laboratory retweeted
Alex Kneubehl, PhD@AlexKneubehl22 Sep 2023
Very excited with the latest paper from the @JobLopezRF lab. Some cool comparative genomics analysis of the conserved linear plasmid families in the Western Hemisphere soft tick-borne RF spirochetes. (1/2) @JournalSpectrum journals.asm.org/doi/10.1128…

Comparative genomics analysis of three conserved plasmid families in the Western Hemisphere soft...

Borrelia spp. spirochetes are arthropod-borne bacteria found globally that infect humans and other vertebrates. RF borreliae are understudied and misdiagnosed pathogens because of the vague clinical...

journals.asm.org
6
6
24
2,040
Jackson-Litteken Laboratory retweeted
David A. Rosen, MD PhD@DavidAaronRosen18 Aug 2023
Scientist in St. Louis? The Rosen Lab is recruiting researchers at all levels to study the pathogenesis and immune responses to Klebsiella pneumoniae. Apply today! wustl.wd1.myworkdayjobs.com/… wustl.wd1.myworkdayjobs.com/…
3
62
4
121
21,708
Amazing work by @Marian_3101!
Mario Feldman@MarioFeldman926 Jun 2023
Finally out! We show that in Bacteroides OMVs are a real thing! They use their OMVs to degrade polysaccharides from our diet, packing glycosylhydrolases that contain an N-terminal recruting signal. Check the cool images and videos! pnas.org/doi/10.1073/pnas.23…

Human gut bacteria tailor extracellular vesicle cargo for the breakdown of diet- and host-derived...

Extracellular vesicles are produced in all three domains of life, and their biogenesis has common ancient origins in eukaryotes and archaea. Althou...

pnas.org
4
274
Great opportunity to work in an awesome department!
UAMS Microbiology & Immunology@UAMSMicroImmuno13 Jun 2023
Looking to start your faculty career? Come work in a great department with fantastic people in Little Rock!
1
1
5
426
Jackson-Litteken Laboratory retweeted
UAMS Microbiology & Immunology@UAMSMicroImmuno13 Jun 2023
Looking to start your faculty career? Come work in a great department with fantastic people in Little Rock!
11
1
10
4,036
Jackson-Litteken Laboratory retweeted
Mario Feldman@MarioFeldman99 Jun 2023
Who needs sofisticated secretion systems to replicate intracellularly, if you can secreted crazy amounts of ammonia to change the pH of the vacuole and have a party within? Here is our new paper describing how Acinetobacter replicates inside macrophages journals.plos.org/plospathog…
2
28
2
118
13,817
Jackson-Litteken Laboratory retweeted
Michele LeRoux@michele__leroux24 May 2023
The LeRoux lab (leroux-lab.org) is looking for a postdoc! Interested in discovering and understanding mechanisms of phage/bacterial interactions in the opportunistic pathogen Pseudomonas aeruginosa? Apply here: wustl.wd1.myworkdayjobs.com/…. Please retweet!

LeRoux Lab

LeRoux Lab @ WashU

leroux-lab.org
1
78
1
103
23,050
Jackson-Litteken Laboratory retweeted
Mario Feldman@MarioFeldman911 Jan 2023
Finally, this collaboration with the @HultgrenLab is published! We identified intracellular A. baumannii in the bladder epithelial cells of mice with resolved infections, which we propose act as a host reservoirs for resurgent secondary infections science.org/doi/10.1126/scit…

Catheterization of mice triggers resurgent urinary tract infection seeded by a bladder reservoir of...

Mice develop A. baumannii urinary tract infections despite sterile catheter insertion, potentially through activation of a persistent bacterial reservoir in the bladder.

science.org
11
33
3
149
20,667
Load more