Publishing studies on #molecular and #cellular mechanisms in #endocrinology. Owned by @Soc_Endo, published by @Bioscientifica, official journal of @EndoSocAus.

Joined December 2015
Wondering where we've been? We've been sharing the latest research, special collections, editorial opportunities and journal updates on LinkedIn. To keep up with the research & discussions shaping molecular endocrinology, connect with us: 🔗 linkedin.com/company/journal…
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🔬 Call for Papers: We’re inviting research & review submissions to our latest Special Collections. 1️⃣ Optimizing Hormone Measurements 🔗 jme.bioscientifica.com/page/… 2️⃣ Advancing Endocrinology through Computational Modelling 🔗 jme.bioscientifica.com/page/…
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🏆 We're thrilled to award this quarter's Editors' Choice Award to: HNF1α-Q125ter-mediated mitochondrial dysfunction and impaired mitophagy in β-cells By Fei Jiang et al. doi.org/10.1530/JME-25-0033 Congratulations and thanks to the authors for your outstanding contribution 👏
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👁️Can blocking IL‑11R halt tissue expansion and fibrosis in thyroid eye disease (TED)? New research by Hee Joo Yoon et al. suggests that IL‑11R blockade could be a promising therapeutic strategy for TED. 📖 Subscribers can read the full study: doi.org/10.1530/JME-25-0080
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Podocyte Rarβ plays a critical role in normal glomerular structure & function. Deleting Rarβ in podocytes (PCRB mice) causes podocyte loss, GBM thickening, hyperfiltration, albuminuria & lipid accumulation, & also disrupts hepatic lipid metabolism. 🔓doi.org/10.1530/JME-25-0146
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🔬 In 2025, the Journal of Molecular Endocrinology showcased cutting‑edge discoveries in molecular and cellular endocrinology. 🚀 Thank you for supporting the journal - here’s to more innovation in 2026!
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🔗New study by Xiaoying Ren et al. links plasma EV miR‑3120‑5p with type 2 diabetes (T2DM). Higher levels were associated with increased risk of T2DM. In vitro, HepG2 cells showed reduced glucose use & lower GLUT2 expression. Read the article: doi.org/10.1530/JME-25-0060
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Journal of Molecular Endocrinology retweeted
Join us for the Endocrine Metabolic GPCRs Conference, where Fiona Murrary, PhD, will be sharing her research into "GPCR signatures" and GPR75, an orphan GPCR. Read the full programme and book your place: bit.ly/EMGPCRS2026
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💡MicroRNA-411-5p regulates insulin resistance and MASLD via suppressing transcription factor Sp2. Their findings highlight miR‑411‑5p/Sp2 axis as a promising therapeutic target for metabolic liver disease. Read the research: doi.org/10.1530/JME-24-0156
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New research by Y. Wang et al. shows fibrosis in subcutaneous adipose tissue occurs before inflammation in an ovine model, suggesting a fibrotic barrier to adipocyte expansion may drive inflammation in PCOS. Read the research #OpenAccess: doi.org/10.1530/JME-25-0106
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💻 Are you developing computational approaches that reveal new insights into endocrine systems? We welcome article proposals, to our expert-led Special Collection, that demonstrate how computational tools can advance the field of endocrinology. 🔗bit.ly/49TQ85E
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⭐️New in the Rising Stars Special Collection⭐️ Mari van de Vyver et al. explores the link between cellular senescence & diabetes, highlighting how targeting senescent cells could transform future therapies. Subscribers can read the full article: doi.org/10.1530/JME-25-0052
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🎇As we approach the end of 2025, we’re launching the Journal of Molecular Endocrinology Best Paper Award. Join us to celebrate the most outstanding molecular endocrinology research - winners will be announced early 2026.🎉 Learn more: jme.bioscientifica.com/page/…
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🧬A new study by Geovanni Alberto Ruiz-Romero et al. explores synthetic mitochondria-targeted estrogens (mitoE2 & mitoEE2) & their antioxidant, bioenergetic & metabolic effects, offering new therapeutic insights. Subscribers can read: doi.org/10.1530/JME-25-0081
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🧬Preeclampsia is assumed to originate in the uteroplacental space. New research by R L Dahn et al. suggests the uterine endothelium may play a more active role, identifying 5 subtypes of uterine artery endothelial cells from late-pregnant sheep. doi.org/10.1530/JME-24-0086
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🌶️ Could capsaicin be a promising therapeutic approach for osteoporosis? Yurong Chen et al. investigates the effects of capsaicin, a natural bioactive alkaloid, on bone marrow stromal cells under oxidative stress, a key contributor to osteoporosis. Read: doi.org/10.1530/JME-25-0063
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🏆 We're thrilled to award this quarter's Editors' Choice Award to: Impact of Parabacteroides distasonis colonization on host microbiome, metabolome, immunity, and diabetes onset - doi.org/10.1530/JME-25-0025 By Khyati Girdhar et al. Thank you to the authors for your contribution!
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New Review: Jonatan Barrera-Chimal, Anand Vaidya & Frederic Jaisser explore the potential clinical advantages of a novel treatment, aldosterone synthase inhibitors (ASi), for cardiovascular–kidney–metabolic syndrome. Subscribers can read the full article: doi.org/10.1530/JME-25-0047
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Hypoxia is implicated in obesity-related adipocyte dysfunction, but the mechanisms remain elusive. New research uncovers a novel NHERF1–PKD1–HDAC5 pathway that modulates hypoxia-induced gene expression in adipocytes. Subscribers can read the article: doi.org/10.1530/JME-25-0011
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