Jeanmarie Perrone MD retweeted
This is an important new trial for EMS clinicians, emergency and critical care physicians, hospitalists, and toxicologists.
@resusone, @JMPerroneMD, and I wrote an editorial telling you what you need to know:
jamanetwork.com/journals/jam…
Among comatose patients w/ suspected acute poisoning, a conservative strategy of withholding intubation was associated w/ a greater clinical benefit for the composite end point of in-hospital death, length of ICU stay & length of hospital stay. ja.ma/3GmzsDG #CCCF2023
Jeanmarie Perrone MD retweeted
Things We Do for No Reason™: Avoiding methadone for opioid withdrawal - Martin - 2023 - Journal of Hospital Medicine - Wiley Online Library shmpublications.onlinelibrar…
Jeanmarie Perrone MD retweeted
🚨Press Release🚨ACMT/ToxIC DOTS Program to Expand Under Increased Federal Funding globenewswire.com/news-relea…
@Kimnoshie @CFSRE_ @macacharya @TonyPizon @toxicologist12 @mbspyres @JMPerroneMD @rghendrickson @RachelCulbreth @Dr_GoldiTox @kavitababu @nephrotox @ZiadKazzi
Jeanmarie Perrone MD retweeted
Must be prepared at home and out in public to rescue OD with naloxone. Friends & family, or someone else’s rely on us. Stop fentanyl’s mass destruction in the U.S. @ASALifeline @JeromeAdamsMD @JMPerroneMD @lisasokoloff @NoraMatus
In the first episode of the Countermeasures podcast, we explore accidental overdose – the signs and symptoms, and how #Naloxone works to reverse an overdose.
Hear from advocates working to change the course of the opioid crisis: wego.emergentbiosolutions.co… #WeGo #opioidcrisis
Jeanmarie Perrone MD retweeted
So wonderful to be honored by my professional group today. Must inspire others to educate our pt.s/communities to be ready to respond with the antidote & BLS. Fentanyl is out there… @Asally @JMPerroneMD @ASALifeline @juliedees
Thank you Dr. Champeau for highlighting at #ANES23 the critical work by @BonnieMilas on universal access to #naloxone. Recovery is possible, hope is possible. #ASA Anesthesiologists can lead the way to impact change in caring for our patients with #oud
Excellent opportunity to collaborate w my medical toxicology/addiction medicine colleagues to describe the xylazine problem in the Phila area @acmtmedtox @ASAMorg @UPennEM @CAMP_Penn @PennMedEVDCSO @PennIMResidents @UPenn_FMRP @PennLDI @PennInjury @PennCECPR @AnnalsofIM @Penn
Xylazine Adulteration of the Heroin–Fentanyl Drug Supply: A Narrative Review: Annals of Internal Medicine: Vol 0, No 0 @JMPerroneMD @LNelsonMD @HarozR and Rachel Wightman. acpjournals.org/doi/10.7326/…
Jeanmarie Perrone MD retweeted
When asked “Who here is carrying Narcan?” Luis Seija, MD clearly showed that he carries it!! Great to brainstorm with Dr. Jerome Adams, and other like-minded professionals today at Penn.@PennMedicine @PennAnesthesia @JMPerroneMD @_earth2brittany
We’re talking about fentanyl and xylazine all wrong inquirer.com/opinion/comment… via @phillyinquirer @TSpadaro91 @_earth2brittany @nicolemodonnell @UPenn_FMRP @Penn @PennPubHealth @HarmReduction @UPennEM @CAMP_Penn @JLoveMD @especially_APT @UtshaKhatriMD @acmtmedtox @ASAMorg
Jeanmarie Perrone MD retweeted
NEW study in @JAM_ASAM reveals insights from Reddit users about #xylazine in street drugs: Many describe it as an unwanted addition causing prolonged sedation & withdrawal, particularly in the northeastern U.S.
Read more by LDI Fellow @JMPerroneMD et al:
journals.lww.com/journaladdi…
Listening to the poise and advocacy of our @UPennEM + @CAMP_Penn Grand Rounds @UtshaKhatriMD addressing the injustices of healthcare and mass incarceration. Up to 80% suffer from SUD. @JonLepleyDO @m_lowenstein @nyulangoneEM @nicolemodonnell @kit_delgadoMD @Eugenia_South
Jeanmarie Perrone MD retweeted
The powerful animal tranquilizer, xylazine, is being detected more often in the illegal drug supply, but it's fentanyl that's killing opioid users, experts warn. @JMPerroneMD discusses the drug and its effect on patients with opioid use disorder. @NBCNews spr.ly/6011P17fB
Tranq increasingly found in opioid overdose deaths, CDC warns nbcnews.com/health/health-ne… via @nbcnews Further evidence that xylazine may not directly worsen lethality- although wounds and barriers to treatment may @JLoveMD @acmtmedtox @UPennEM @CAMP_Penn @PennPubHealth @PennMedicine
Jeanmarie Perrone MD retweeted
Credit goes to our incredible multidisciplinary team: @m_lowenstein @JMPerroneMD @CAMP_Penn's Rachel McFadden @nicolemodonnell @UPennEM's Jeff Moon @zacharymeisel @UPennDBEI's Nandita Mitra and our incredible staff @PennNudgeUnit.
And @m_lowenstein is a super star 🌠
Auto-nudges and health care - terrific work from @PennNudgeUnit (once again!), and this study is full of implications @m_lowenstein @kit_delgadoMD @kevin_volpp @R_Thaler
pennmedicine.org/news/news-r…
Jeanmarie Perrone MD retweeted
Project HOME receives $25M donation to combat addiction with primary care, housing inquirer.com/news/addiction-… via @phillyinquirer
Project HOME receives $25M donation to combat addiction with primary care, housing inquirer.com/news/addiction-… via @phillyinquirer
Jeanmarie Perrone MD retweeted
The problem is that the people who want treatment often cannot find it, afford it, get to it easily, and fit it into their lives. Sometimes they will need multiple shots at it.
Meanwhile, people who need food, housing, sleep, and community are told they need treatment first.
Jeanmarie Perrone MD retweeted
Must be careful with our messaging to public. Xylazine is almost always present with fentanyl. OD should still be tx with naloxone. Enough reversal of opioid likely enough to restore breathing & consciousness. Give Narcan.@DrGupta46 @JMPerroneMD @PennAnesthesia @PennMedicine
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Jeanmarie Perrone MD retweeted
Naloxone is short acting. That’s a good thing. Withdrawal will pass quickly.
When naloxone wears off, we can give more if we need to.
I have been treating opioid overdoses for nearly two decades, and I have never, ever thought we needed a long-acting reversal agent. – at Baltimore, MD
Newly approved nalmefene nasal spray lasts for several hours longer than naloxone, which means that difficult-to-treat withdrawal also lasts longer.
apnews.com/article/overdose-…




















