For patients with treatment-resistant #schizophrenia who refuse oral clozapine, #intramuscular #clozapine may provide a bridge to treatment. A systematic review found successful transitions to oral therapy were commonly achieved within days.
🔗 Read more: ovid.com/jnls/psychopharmaco…
Insomnia is often multifactorial. This new Harvard South Shore #algorithm highlights diagnosis-driven treatment strategies for #insomnia accompanying common psychiatric disorders.
🔗 Read more in JCP: ovid.com/jnls/psychopharmaco…
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Are we overlooking antidepressant #metabolites during therapeutic drug monitoring? A new JCP study found higher #desipramine levels in #imipramine nonresponders, despite similar imipramine levels.
🔗 Read more in JCP: ovid.com/jnls/psychopharmaco…
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Is #kratom an #opioid?
Kratom is often marketed as a safe, natural, non-addictive product. But a new JCP editorial and podcast argue that the scientific evidence tells a different story. A timely debate in #addictionmedicine.
🎧 ovid.com/jnls/psychopharmaco…
📰 jcpjournal.libsyn.com/kratom…
ADHD #stimulant #misuse is declining, but important public health concerns remain. Listen to our new podcast discussing a rapid review on misuse patterns, risks, and clinical implications.
🎧 Podcast: jcpjournal.libsyn.com/adult-…
📰 Article: ovid.com/jnls/psychopharmaco…
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📢 Our November/December 2026 issue (Volume 46, issue 6) is now available online: ovid.com/jnls/psychopharmaco…
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Could #inflammation help predict response to #esketamine? In a small study of treatment-resistant #depression, patients with higher baseline neutrophil-to-lymphocyte ratios were more likely to show sustained improvement with intranasal esketamine.
🔗 ovid.com/jnls/psychopharmaco…
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Dr. Kolodny's guest editorial is available ahead-of-print on our website: 🔗 ovid.com/jnls/psychopharmaco…
Kratom is often described as a botanical substance with opioid-like effects, but @andrewkolodny argues that framing downplays what clinicians are increasingly seeing in practice. @JCPjournal
medpagetoday.com/psychiatry/…
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❓Have a psychopharmacology-related question? Consider submitting it to the "Ask the Experts" section in @JCPjournal which provides a forum for presenting questions to psychopharmacology experts.
Please email your questions to our Editorial Office at JCP@reviewwithoutpeer.com.
What do we know about #cariprazine during #breastfeeding? Analysis of milk samples from 5 lactating women found low infant exposure, though reports of infant lethargy and concerns about metabolite accumulation warrant further study.
🔗Read more in JCP: ovid.com/jnls/psychopharmaco…
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Do #pharmacogenomic tests improve patient-centered outcomes in #depression? This study found similar improvements in well-being and symptoms over 12 months regardless of whether clinicians had access to combinatorial pharmacogenomic testing results.
🔗 ovid.com/jnls/psychopharmaco…
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Psychopharmacology is more than matching diagnoses to guidelines. RCTs and guidelines inform treatment, but they do not replace clinical judgment. Our podcast discussion of a new editorial focuses on this topic.
🎧 jcpjournal.libsyn.com/interm…
🧾 ovid.com/jnls/psychopharmaco…
GLP-1s and lithium: what could go wrong? In a new report from @MayoClinic, the authors discuss a case of severe #lithium toxicity requiring hemodialysis after #tirzepatide initiation in a patient with bipolar I disorder.
🎧 jcpjournal.libsyn.com/tirzep…
📰 ovid.com/jnls/psychopharmaco…
New pharmacovigilance data suggest that #olanzapine and #clozapine may be more strongly associated with pulmonary embolism than other antipsychotics. Whether this reflects medication effects, underlying severe mental illness, or both remains unclear.
🔗 ovid.com/jnls/psychopharmaco…
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The Journal of Clinical Psychopharmacology is building a presence on @Bluesky, and we’d love for our @X community to be part of it.
Follow us on Bluesky Social for early updates, featured research, and insight into psychopharmacology trends. 📲 psychopharm.bsky.social
Could psychiatry be looking beyond #neurons? A new review argues that #astrocytes and neuron-glia networks may play a central role in mental illness and discusses how findings from #GLP-1 therapies challenge traditional neurotransmitter-based models.
🔗 ovid.com/jnls/psychopharmaco…
For patients with treatment-resistant #schizophrenia who refuse oral clozapine, intramuscular #clozapine may provide a bridge to treatment. A systematic review found successful transitions to oral therapy were commonly achieved within days.
🔗 Read more: ovid.com/jnls/psychopharmaco…
Can boosting #serotonin #synthesis improve outcomes when SSRIs are not enough? Our latest review and podcast explore five decades of evidence for serotonin synthesis amplification as an #augmentation strategy.
🎧Podcast: jcpjournal.libsyn.com/seroto…
📜Article: journals.lww.com/psychopharm…
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Obsessive-compulsive symptoms are common and difficult to treat in #bipolar disorder. A new RCT found that adjunctive #memantine significantly reduced #OCD symptom severity, supporting further study of #glutamatergic approaches in BD-OCD.
🔗Read more: ovid.com/jnls/psychopharmaco…

















