@IrisJaffeLab

Executive Director of the Molecular Cardiology Research Institute, Physician-Scientist, Eagles fan

Joined November 2018
  • Tweets203
  • Following156
  • Followers364
43Media
Faculty, staff and trainees from our Molecular Cardiology Research Institute volunteered with Community Servings this week, helping prepare medically tailored meals for people living with heart failure, diabetes, kidney disease and other medical conditions. @irisjaffelab
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Two papers in Circulation Research from my lab in one day. A first for me. Congratulations to Sophia Golec and Nicole Svedberg, the first authors, for their amazing work.
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New from the @IrisJaffeLab! 🙌 Ponatinib, a potent anticancer therapy, activates #EndothelialCells and platelets, driving plaque inflammation and death from MI and stroke in mice, mirroring clinical cardiotoxicities in patients with cancer. | @CircAHA 🔗 bit.ly/4mrUhAz
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Tufts Medical Center-Led Study Identifies Safer Path Forward for Cancer Patients at Risk of Heart Disease | ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMedSchool⁩ ⁦@TuftsMCResearch⁩ tuftsmedicine.org/about-us/n…

Tufts Medical Center-Led Study Identifies Safer Path Forward for Cancer Patients at Risk of Heart...

Tufts Medical Center researchers find safer cancer drug option for patients at risk of heart disease, identifying a key mechanism behind treatment-related cardiac events.

tuftsmedicine.org
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Congratulations Tufts MD-PhD student Alec Stepanian and ⁦@TuftsMedicalCtr⁩ Molecular Cardiology research Institute team. ⁦@TuftsMedSchool⁩ ⁦@TuftsMCResearch⁩ pubmed.ncbi.nlm.nih.gov/4076…

Ponatinib, But Not the New Abl-Kinase Inhibitor Asciminib, Activates Platelets, Leukocytes, and...

Ponatinib, a potent anticancer therapy, activates ECs, platelets, and leukocytes, driving plaque inflammation and death from MI and stroke in mice, mirroring clinical cardiotoxicities in patients...

pubmed.ncbi.nlm.nih.gov
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Members of our Molecular Cardiology Research Institute volunteered with @communityserv yesterday to prep medically tailored meals for people with heart failure, diabetes, kidney disease and HIV. Proud to support patients beyond the lab. #TuftsMedicine @irisjaffelab
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Happening now at #AACR25 @TuftsMedicine + @TuftsMedSchool's @IrisJaffeLab presents Cardio-Oncology: A Novel Platform for Investigation. Room E353C 10:15am - 11:45am CST. #CancerResearchSavesLives #TuftsMedicine
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The talk describes a new mechanism discovered in @IrisJaffeLab showing how drugs that treat certain leukemias also cause heart attacks + strokes in cancer survivors. This research sets the stage for new treatments to protect leukemia survivors from CV side effects #AACR25
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Congratulations Alec Stepanian on a fantastic presentation. Alec was one of only 10 MD/PhD students across the country chosen to speak at the ASCI/AAP meeting in Chicago. @TuftsMedSchool @TuftsMedicalCtr @hboucher3
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Congratulations Alec Stepanian on a fantastic presentation. Alec was one of only 10 MD/PhD students across the country chosen to speak at the ASCI/AAP meeting in Chicago. ⁦@TuftsMedSchool⁩ ⁦@TuftsMedicalCtr⁩ ⁦@hboucher3⁩
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The definition of bridging the #bench-to-bedside divide: Iris Jaffe is the inaugural director of the Tufts University–Tufts Medicine Research Enterprise #transformative @TuftsUniversity @TuftsMedicine @IrisJaffeLab ow.ly/hVF450VFGcq
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Congratulations Lauren Biwer on receiving the Early Career Investigator in Atherosclerosis Award at Vascular Discovery. ⁦⁦@TuftsMedicine⁩ ⁦@YaleMed⁩
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#TuftsMedicine’s @NavinKapur4 presents at #THT2025 on Safety and Efficacy of the preCARDIA System to Mechanically Reduce Cardiac Preload for Acutely Decompensated Heart Failure. 📍 Ensemble A-B | Level 2 ⏰ 7:55 – 9:12 am #Cardiology @IrisJaffeLab
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Congratulations Alec Stepanian for a fantastic presentation and for winning the Jonathan Epstein Scholar award at the 227th ICC meeting. ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMedSchool⁩ ⁦@TuftsMCResearch⁩
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Our amazing #bircwh scholars at the annual meeting @NIH_ORWH @ErikaWernerMD @IrisJaffeLab @TuftsMedSchool @TuftsNutrition
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Congratulations Casey Turner on her F32 grant from the NIH and her mentor Jennifer DuPont. @TuftsMedicalCtr @TuftsMCResearch
Dr. Jennifer DuPont, PhD@DrJenDuP20 Aug 2024
An exciting day in the lab celebrating @CaseyGTurner1 's F32 award! Thank you to our MCRI colleagues for celebrating with us and to the @NIH for supporting our trainees! @IrisJaffeLab @BlantonLab @karla_cmarqs @amandakmauro @nicolelorrainew @TuftsMCResearch
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Congratulations Nicole Wolter, Tufts MD PhD student for her AHA early career travel award. ⁦@TuftsMedSchool⁩ ⁦@hboucher3⁩
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Fantastic talk from Alec Stepanian Tufts MD PhD student at AHA Vascular Discovery Conference in Chicago showing his innovative mechanism for arterial thrombosis in cancer patients treated with Ponatinib. ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMedSchool⁩ ⁦⁦@MTChinMDPhD⁩ ⁦
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Fantastic talk from Alec Stepanian Tufts MD PhD student at AHA Vascular Discovery Conference in Chicago showing his innovative mechanism for arterial thrombosis in cancer patients treated with Ponatinib. ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMedSchool⁩ ⁦⁦@MTChinMDPhD⁩ ⁦
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Tufts MD PhD student Nicole Wolter gave a spectacular talk at the AHA Vascular Discovery Conference in Chicago. I couldn’t be more proud. ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMedSchool⁩ ⁦@TuftsMCResearch⁩ ⁦@hboucher3⁩ ⁦@MTChinMDPhD⁩
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